| Full name: intraflagellar transport 52 | Alias Symbol: CGI-53|NGD5|dJ1028D15.1|NGD2 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 51098 | HGNC ID: HGNC:15901 | Ensembl Gene: ENSG00000101052 | OMIM ID: 617094 |
| Drug and gene relationship at DGIdb | |||
Expression of IFT52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFT52 | 51098 | 218709_s_at | 0.3114 | 0.5394 | |
| GSE20347 | IFT52 | 51098 | 218709_s_at | 0.3805 | 0.0304 | |
| GSE23400 | IFT52 | 51098 | 218709_s_at | 0.1870 | 0.0000 | |
| GSE26886 | IFT52 | 51098 | 218709_s_at | 0.3948 | 0.0113 | |
| GSE29001 | IFT52 | 51098 | 218709_s_at | 0.2740 | 0.1814 | |
| GSE38129 | IFT52 | 51098 | 218709_s_at | 0.3690 | 0.0111 | |
| GSE45670 | IFT52 | 51098 | 218709_s_at | -0.1052 | 0.5380 | |
| GSE53622 | IFT52 | 51098 | 14478 | 0.3186 | 0.0005 | |
| GSE53624 | IFT52 | 51098 | 2960 | 0.4000 | 0.0000 | |
| GSE63941 | IFT52 | 51098 | 218709_s_at | -0.2158 | 0.6027 | |
| GSE77861 | IFT52 | 51098 | 218709_s_at | 0.1706 | 0.4614 | |
| GSE97050 | IFT52 | 51098 | A_33_P3368500 | 0.1573 | 0.7493 | |
| SRP007169 | IFT52 | 51098 | RNAseq | 0.0916 | 0.8225 | |
| SRP008496 | IFT52 | 51098 | RNAseq | 0.3470 | 0.2354 | |
| SRP064894 | IFT52 | 51098 | RNAseq | 0.2500 | 0.1148 | |
| SRP133303 | IFT52 | 51098 | RNAseq | 0.5019 | 0.0000 | |
| SRP159526 | IFT52 | 51098 | RNAseq | 0.4838 | 0.0756 | |
| SRP193095 | IFT52 | 51098 | RNAseq | 0.2041 | 0.0610 | |
| SRP219564 | IFT52 | 51098 | RNAseq | 0.2462 | 0.5076 | |
| TCGA | IFT52 | 51098 | RNAseq | 0.1732 | 0.0071 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFT52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFT52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFT52 | 51098 | 13 | 2 | 15 | |
| GSE20123 | IFT52 | 51098 | 13 | 2 | 15 | |
| GSE43470 | IFT52 | 51098 | 12 | 1 | 30 | |
| GSE46452 | IFT52 | 51098 | 29 | 0 | 30 | |
| GSE47630 | IFT52 | 51098 | 24 | 0 | 16 | |
| GSE54993 | IFT52 | 51098 | 0 | 17 | 53 | |
| GSE54994 | IFT52 | 51098 | 25 | 0 | 28 | |
| GSE60625 | IFT52 | 51098 | 0 | 0 | 11 | |
| GSE74703 | IFT52 | 51098 | 10 | 1 | 25 | |
| GSE74704 | IFT52 | 51098 | 9 | 0 | 11 | |
| TCGA | IFT52 | 51098 | 47 | 2 | 47 |
Total number of gains: 182; Total number of losses: 25; Total Number of normals: 281.
Somatic mutations of IFT52:
Generating mutation plots.
Highly correlated genes for IFT52:
Showing top 20/1161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFT52 | FARS2 | 0.825116 | 3 | 0 | 3 |
| IFT52 | RECQL | 0.734528 | 4 | 0 | 4 |
| IFT52 | FAF1 | 0.731476 | 3 | 0 | 3 |
| IFT52 | IQCK | 0.729194 | 5 | 0 | 5 |
| IFT52 | EFHD2 | 0.728872 | 3 | 0 | 3 |
| IFT52 | ASCC3 | 0.716827 | 3 | 0 | 3 |
| IFT52 | SPEN | 0.716716 | 3 | 0 | 3 |
| IFT52 | MEX3B | 0.71274 | 3 | 0 | 3 |
| IFT52 | U2AF1 | 0.711829 | 3 | 0 | 3 |
| IFT52 | HYLS1 | 0.710823 | 3 | 0 | 3 |
| IFT52 | BOD1 | 0.710709 | 6 | 0 | 6 |
| IFT52 | ZNF627 | 0.705919 | 5 | 0 | 5 |
| IFT52 | EARS2 | 0.705283 | 3 | 0 | 3 |
| IFT52 | RPS6KA3 | 0.70384 | 4 | 0 | 3 |
| IFT52 | CHD4 | 0.700788 | 4 | 0 | 3 |
| IFT52 | DDB1 | 0.700722 | 4 | 0 | 3 |
| IFT52 | USP42 | 0.700671 | 4 | 0 | 4 |
| IFT52 | FAM161A | 0.700658 | 4 | 0 | 4 |
| IFT52 | CHCHD6 | 0.699336 | 4 | 0 | 3 |
| IFT52 | LRRC58 | 0.698023 | 3 | 0 | 3 |
For details and further investigation, click here
