| Full name: mitochondrial ribosomal protein S15 | Alias Symbol: FLJ11564 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 64960 | HGNC ID: HGNC:14504 | Ensembl Gene: ENSG00000116898 | OMIM ID: 611979 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MRPS15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS15 | 64960 | 226296_s_at | 0.2952 | 0.4517 | |
| GSE20347 | MRPS15 | 64960 | 221437_s_at | -0.0949 | 0.6123 | |
| GSE23400 | MRPS15 | 64960 | 221437_s_at | 0.1379 | 0.0111 | |
| GSE26886 | MRPS15 | 64960 | 226296_s_at | 0.2028 | 0.1984 | |
| GSE29001 | MRPS15 | 64960 | 221437_s_at | 0.0587 | 0.9033 | |
| GSE38129 | MRPS15 | 64960 | 221437_s_at | 0.0863 | 0.5409 | |
| GSE45670 | MRPS15 | 64960 | 226296_s_at | 0.2652 | 0.0157 | |
| GSE53622 | MRPS15 | 64960 | 88806 | 0.3621 | 0.0000 | |
| GSE53624 | MRPS15 | 64960 | 88806 | 0.5247 | 0.0000 | |
| GSE63941 | MRPS15 | 64960 | 226296_s_at | 0.4420 | 0.2251 | |
| GSE77861 | MRPS15 | 64960 | 226296_s_at | 0.0800 | 0.7598 | |
| GSE97050 | MRPS15 | 64960 | A_23_P114826 | 0.0359 | 0.8983 | |
| SRP007169 | MRPS15 | 64960 | RNAseq | 0.4118 | 0.3053 | |
| SRP008496 | MRPS15 | 64960 | RNAseq | 0.1444 | 0.6153 | |
| SRP064894 | MRPS15 | 64960 | RNAseq | 0.6084 | 0.0321 | |
| SRP133303 | MRPS15 | 64960 | RNAseq | 0.4855 | 0.0042 | |
| SRP159526 | MRPS15 | 64960 | RNAseq | 0.2300 | 0.2524 | |
| SRP193095 | MRPS15 | 64960 | RNAseq | 0.0612 | 0.6753 | |
| SRP219564 | MRPS15 | 64960 | RNAseq | -0.1672 | 0.4935 | |
| TCGA | MRPS15 | 64960 | RNAseq | 0.1098 | 0.0443 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPS15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS15 | 64960 | 3 | 5 | 22 | |
| GSE20123 | MRPS15 | 64960 | 3 | 4 | 23 | |
| GSE43470 | MRPS15 | 64960 | 7 | 2 | 34 | |
| GSE46452 | MRPS15 | 64960 | 4 | 1 | 54 | |
| GSE47630 | MRPS15 | 64960 | 8 | 3 | 29 | |
| GSE54993 | MRPS15 | 64960 | 1 | 1 | 68 | |
| GSE54994 | MRPS15 | 64960 | 11 | 2 | 40 | |
| GSE60625 | MRPS15 | 64960 | 0 | 0 | 11 | |
| GSE74703 | MRPS15 | 64960 | 6 | 1 | 29 | |
| GSE74704 | MRPS15 | 64960 | 1 | 0 | 19 | |
| TCGA | MRPS15 | 64960 | 11 | 18 | 67 |
Total number of gains: 55; Total number of losses: 37; Total Number of normals: 396.
Somatic mutations of MRPS15:
Generating mutation plots.
Highly correlated genes for MRPS15:
Showing top 20/877 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS15 | CEP63 | 0.831582 | 3 | 0 | 3 |
| MRPS15 | EBNA1BP2 | 0.8162 | 4 | 0 | 4 |
| MRPS15 | SPNS1 | 0.795947 | 3 | 0 | 3 |
| MRPS15 | SLC35A5 | 0.765987 | 3 | 0 | 3 |
| MRPS15 | ARFGEF2 | 0.758986 | 3 | 0 | 3 |
| MRPS15 | MED26 | 0.751831 | 3 | 0 | 3 |
| MRPS15 | COPS7A | 0.744782 | 3 | 0 | 3 |
| MRPS15 | NEMF | 0.742978 | 3 | 0 | 3 |
| MRPS15 | ZNF213 | 0.731329 | 3 | 0 | 3 |
| MRPS15 | DAPK3 | 0.723377 | 3 | 0 | 3 |
| MRPS15 | CSRNP2 | 0.72054 | 3 | 0 | 3 |
| MRPS15 | TMEM189 | 0.720097 | 3 | 0 | 3 |
| MRPS15 | EIF3I | 0.719496 | 9 | 0 | 9 |
| MRPS15 | SCNM1 | 0.719046 | 3 | 0 | 3 |
| MRPS15 | COPS2 | 0.71834 | 4 | 0 | 3 |
| MRPS15 | PPP2R5E | 0.71759 | 4 | 0 | 4 |
| MRPS15 | SPCS2 | 0.716374 | 3 | 0 | 3 |
| MRPS15 | CNOT1 | 0.711992 | 3 | 0 | 3 |
| MRPS15 | AGTRAP | 0.706142 | 3 | 0 | 3 |
| MRPS15 | ARF3 | 0.703932 | 3 | 0 | 3 |
For details and further investigation, click here
