| Full name: POP5 homolog, ribonuclease P/MRP subunit | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 51367 | HGNC ID: HGNC:17689 | Ensembl Gene: ENSG00000167272 | OMIM ID: 609992 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of POP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POP5 | 51367 | 204839_at | 0.3129 | 0.5721 | |
| GSE20347 | POP5 | 51367 | 204839_at | 0.6839 | 0.0010 | |
| GSE23400 | POP5 | 51367 | 204839_at | 0.7003 | 0.0000 | |
| GSE26886 | POP5 | 51367 | 204839_at | 0.8287 | 0.0000 | |
| GSE29001 | POP5 | 51367 | 204839_at | 0.6967 | 0.0887 | |
| GSE38129 | POP5 | 51367 | 204839_at | 0.5743 | 0.0001 | |
| GSE45670 | POP5 | 51367 | 204839_at | 0.5274 | 0.0003 | |
| GSE53622 | POP5 | 51367 | 61961 | 0.1861 | 0.0127 | |
| GSE53624 | POP5 | 51367 | 61961 | 0.6474 | 0.0000 | |
| GSE63941 | POP5 | 51367 | 204839_at | 0.5263 | 0.0763 | |
| GSE77861 | POP5 | 51367 | 204839_at | 0.3559 | 0.0991 | |
| GSE97050 | POP5 | 51367 | A_33_P3218584 | 0.1371 | 0.5459 | |
| SRP007169 | POP5 | 51367 | RNAseq | 0.4119 | 0.2564 | |
| SRP008496 | POP5 | 51367 | RNAseq | 0.6614 | 0.0093 | |
| SRP064894 | POP5 | 51367 | RNAseq | 0.5945 | 0.0300 | |
| SRP133303 | POP5 | 51367 | RNAseq | 0.0741 | 0.6884 | |
| SRP159526 | POP5 | 51367 | RNAseq | 0.5978 | 0.0899 | |
| SRP193095 | POP5 | 51367 | RNAseq | 0.0007 | 0.9956 | |
| SRP219564 | POP5 | 51367 | RNAseq | -0.0390 | 0.9197 | |
| TCGA | POP5 | 51367 | RNAseq | 0.2298 | 0.0030 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POP5 | 51367 | 6 | 2 | 22 | |
| GSE20123 | POP5 | 51367 | 6 | 2 | 22 | |
| GSE43470 | POP5 | 51367 | 2 | 2 | 39 | |
| GSE46452 | POP5 | 51367 | 9 | 1 | 49 | |
| GSE47630 | POP5 | 51367 | 9 | 3 | 28 | |
| GSE54993 | POP5 | 51367 | 0 | 5 | 65 | |
| GSE54994 | POP5 | 51367 | 7 | 6 | 40 | |
| GSE60625 | POP5 | 51367 | 0 | 0 | 11 | |
| GSE74703 | POP5 | 51367 | 2 | 1 | 33 | |
| GSE74704 | POP5 | 51367 | 3 | 2 | 15 | |
| TCGA | POP5 | 51367 | 20 | 11 | 65 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of POP5:
Generating mutation plots.
Highly correlated genes for POP5:
Showing top 20/1549 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POP5 | RFNG | 0.863274 | 3 | 0 | 3 |
| POP5 | UBA52 | 0.790853 | 3 | 0 | 3 |
| POP5 | SYNJ1 | 0.771808 | 3 | 0 | 3 |
| POP5 | PACS1 | 0.760614 | 3 | 0 | 3 |
| POP5 | DTX4 | 0.756104 | 3 | 0 | 3 |
| POP5 | MCCC1 | 0.753073 | 3 | 0 | 3 |
| POP5 | ALG10 | 0.749039 | 4 | 0 | 3 |
| POP5 | PIK3R3 | 0.732975 | 4 | 0 | 4 |
| POP5 | MOB3C | 0.726285 | 3 | 0 | 3 |
| POP5 | VPS37C | 0.722792 | 3 | 0 | 3 |
| POP5 | STK11IP | 0.718767 | 3 | 0 | 3 |
| POP5 | LIPT1 | 0.718694 | 3 | 0 | 3 |
| POP5 | C10orf55 | 0.717675 | 3 | 0 | 3 |
| POP5 | CDK5RAP2 | 0.716988 | 3 | 0 | 3 |
| POP5 | TRMT5 | 0.712987 | 4 | 0 | 4 |
| POP5 | CSRNP2 | 0.710269 | 4 | 0 | 4 |
| POP5 | MFF | 0.707958 | 3 | 0 | 3 |
| POP5 | SMARCD2 | 0.705128 | 3 | 0 | 3 |
| POP5 | ALG1 | 0.704078 | 4 | 0 | 4 |
| POP5 | FARS2 | 0.70293 | 4 | 0 | 3 |
For details and further investigation, click here
