ZSCAN25

 

Full name: zinc finger and SCAN domain containing 25 Alias Symbol: FLJ32468
Type: protein-coding gene Cytoband: 7q22.1
Entrez ID: 221785 HGNC ID: HGNC:21961 Ensembl Gene: ENSG00000197037 OMIM ID: 
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of ZSCAN25:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZSCAN25 221785 228138_at 0.2851 0.5065
GSE26886 ZSCAN25 221785 228138_at 0.4871 0.0802
GSE45670 ZSCAN25 221785 228138_at -0.0438 0.8515
GSE53622 ZSCAN25 221785 52528 0.3689 0.0000
GSE53624 ZSCAN25 221785 52528 0.5294 0.0000
GSE63941 ZSCAN25 221785 242621_at 0.9452 0.0204
GSE77861 ZSCAN25 221785 228138_at 0.1818 0.1462
SRP007169 ZSCAN25 221785 RNAseq 0.0566 0.8704
SRP008496 ZSCAN25 221785 RNAseq 0.6253 0.0613
SRP064894 ZSCAN25 221785 RNAseq -0.0811 0.5645
SRP133303 ZSCAN25 221785 RNAseq 0.0740 0.6379
SRP159526 ZSCAN25 221785 RNAseq 0.0791 0.7065
SRP193095 ZSCAN25 221785 RNAseq 0.0061 0.9679
SRP219564 ZSCAN25 221785 RNAseq 0.2841 0.4545

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ZSCAN25 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of ZSCAN25:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZSCAN25 221785 13 0 17
GSE20123 ZSCAN25 221785 13 0 17
GSE43470 ZSCAN25 221785 6 1 36
GSE46452 ZSCAN25 221785 11 1 47
GSE47630 ZSCAN25 221785 8 3 29
GSE54993 ZSCAN25 221785 1 9 60
GSE54994 ZSCAN25 221785 15 4 34
GSE60625 ZSCAN25 221785 0 0 11
GSE74703 ZSCAN25 221785 6 1 29
GSE74704 ZSCAN25 221785 9 0 11
TCGA ZSCAN25 221785 53 5 38

Total number of gains: 135; Total number of losses: 24; Total Number of normals: 329.  


 

Somatic mutations of ZSCAN25:

 

Generating mutation plots.

 

Highly correlated genes for ZSCAN25:

 

Showing top 20/239 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZSCAN25ACTR60.754554303
ZSCAN25MTERF10.728975404
ZSCAN25PRDM150.719865303
ZSCAN25NR2C2AP0.713719303
ZSCAN25ELK40.695222303
ZSCAN25KXD10.694621303
ZSCAN25SMARCD10.691278404
ZSCAN25SPSB20.690746303
ZSCAN25HPS30.688392303
ZSCAN25EIF2B50.676235303
ZSCAN25ZNF3940.676192404
ZSCAN25RAD23A0.674913303
ZSCAN25FXYD30.666376303
ZSCAN25FAF10.661168303
ZSCAN25JTB0.658715403
ZSCAN25TRIM110.656761303
ZSCAN25IRAK10.656696303
ZSCAN25RNF1380.656076303
ZSCAN25GUSB0.654166403
ZSCAN25URI10.65406403

For details and further investigation, click here