| Full name: FAM161 centrosomal protein A | Alias Symbol: FLJ13305 | ||
| Type: protein-coding gene | Cytoband: 2p15 | ||
| Entrez ID: 84140 | HGNC ID: HGNC:25808 | Ensembl Gene: ENSG00000170264 | OMIM ID: 613596 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM161A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM161A | 84140 | 242584_at | 0.7416 | 0.0431 | |
| GSE26886 | FAM161A | 84140 | 242584_at | 1.2074 | 0.0014 | |
| GSE45670 | FAM161A | 84140 | 242584_at | 0.1401 | 0.6622 | |
| GSE53622 | FAM161A | 84140 | 29882 | 0.7593 | 0.0000 | |
| GSE53624 | FAM161A | 84140 | 87471 | 0.8137 | 0.0000 | |
| GSE63941 | FAM161A | 84140 | 242584_at | 1.5417 | 0.0226 | |
| GSE77861 | FAM161A | 84140 | 1557385_at | 0.0896 | 0.4883 | |
| GSE97050 | FAM161A | 84140 | A_32_P82189 | 0.2261 | 0.4131 | |
| SRP007169 | FAM161A | 84140 | RNAseq | 1.2831 | 0.0387 | |
| SRP008496 | FAM161A | 84140 | RNAseq | 1.1719 | 0.0070 | |
| SRP064894 | FAM161A | 84140 | RNAseq | 0.3440 | 0.0701 | |
| SRP133303 | FAM161A | 84140 | RNAseq | 0.4110 | 0.0548 | |
| SRP159526 | FAM161A | 84140 | RNAseq | 0.9457 | 0.0199 | |
| SRP193095 | FAM161A | 84140 | RNAseq | 0.3287 | 0.0181 | |
| SRP219564 | FAM161A | 84140 | RNAseq | 0.2113 | 0.5988 | |
| TCGA | FAM161A | 84140 | RNAseq | -0.2278 | 0.0596 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by FAM161A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM161A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM161A | 84140 | 12 | 0 | 18 | |
| GSE20123 | FAM161A | 84140 | 12 | 0 | 18 | |
| GSE43470 | FAM161A | 84140 | 7 | 0 | 36 | |
| GSE46452 | FAM161A | 84140 | 2 | 3 | 54 | |
| GSE47630 | FAM161A | 84140 | 8 | 0 | 32 | |
| GSE54993 | FAM161A | 84140 | 0 | 6 | 64 | |
| GSE54994 | FAM161A | 84140 | 12 | 0 | 41 | |
| GSE60625 | FAM161A | 84140 | 0 | 3 | 8 | |
| GSE74703 | FAM161A | 84140 | 7 | 0 | 29 | |
| GSE74704 | FAM161A | 84140 | 10 | 0 | 10 | |
| TCGA | FAM161A | 84140 | 36 | 2 | 58 |
Total number of gains: 106; Total number of losses: 14; Total Number of normals: 368.
Somatic mutations of FAM161A:
Generating mutation plots.
Highly correlated genes for FAM161A:
Showing top 20/1082 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM161A | TMC7 | 0.829164 | 3 | 0 | 3 |
| FAM161A | PLAGL2 | 0.825116 | 3 | 0 | 3 |
| FAM161A | SUMO3 | 0.798981 | 3 | 0 | 3 |
| FAM161A | FZD6 | 0.798529 | 3 | 0 | 3 |
| FAM161A | C12orf49 | 0.793538 | 3 | 0 | 3 |
| FAM161A | MCM3AP | 0.78304 | 3 | 0 | 3 |
| FAM161A | SPATC1L | 0.777665 | 3 | 0 | 3 |
| FAM161A | CCNJ | 0.777175 | 3 | 0 | 3 |
| FAM161A | CPNE8 | 0.776741 | 3 | 0 | 3 |
| FAM161A | VPS13B | 0.775666 | 3 | 0 | 3 |
| FAM161A | ACACA | 0.771828 | 3 | 0 | 3 |
| FAM161A | ZNF680 | 0.764423 | 3 | 0 | 3 |
| FAM161A | SRSF10 | 0.762554 | 3 | 0 | 3 |
| FAM161A | ZNF121 | 0.759625 | 3 | 0 | 3 |
| FAM161A | ATG4C | 0.757223 | 3 | 0 | 3 |
| FAM161A | TSN | 0.75083 | 4 | 0 | 4 |
| FAM161A | DEDD | 0.750824 | 3 | 0 | 3 |
| FAM161A | BAG6 | 0.748808 | 3 | 0 | 3 |
| FAM161A | ZKSCAN5 | 0.74512 | 3 | 0 | 3 |
| FAM161A | MRPL37 | 0.740393 | 3 | 0 | 3 |
For details and further investigation, click here
