NDC1

 

Full name: NDC1 transmembrane nucleoporin Alias Symbol: FLJ10407|NET3
Type: protein-coding gene Cytoband: 1p32.3
Entrez ID: 55706 HGNC ID: HGNC:25525 Ensembl Gene: ENSG00000058804 OMIM ID: 610115
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NDC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NDC1 55706 234672_s_at 1.0519 0.1601
GSE20347 NDC1 55706 218073_s_at 0.9007 0.0007
GSE23400 NDC1 55706 218073_s_at 0.8285 0.0000
GSE26886 NDC1 55706 234672_s_at 0.5591 0.0046
GSE29001 NDC1 55706 218073_s_at 0.5058 0.2600
GSE38129 NDC1 55706 218073_s_at 1.2053 0.0000
GSE45670 NDC1 55706 234672_s_at 0.5678 0.0004
GSE53622 NDC1 55706 40762 0.6424 0.0000
GSE53624 NDC1 55706 26611 0.9663 0.0000
GSE63941 NDC1 55706 234672_s_at 1.1530 0.0060
GSE77861 NDC1 55706 234672_s_at 0.5248 0.2369
SRP007169 NDC1 55706 RNAseq 1.1872 0.0134
SRP008496 NDC1 55706 RNAseq 0.7855 0.0044
SRP064894 NDC1 55706 RNAseq 0.6958 0.0017
SRP133303 NDC1 55706 RNAseq 0.8669 0.0000
SRP159526 NDC1 55706 RNAseq 0.8877 0.0768
SRP193095 NDC1 55706 RNAseq 0.3949 0.0042
SRP219564 NDC1 55706 RNAseq 0.7878 0.1070

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by NDC1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of NDC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NDC1 55706 3 4 23
GSE20123 NDC1 55706 3 3 24
GSE43470 NDC1 55706 6 2 35
GSE46452 NDC1 55706 2 1 56
GSE47630 NDC1 55706 8 4 28
GSE54993 NDC1 55706 0 0 70
GSE54994 NDC1 55706 10 2 41
GSE60625 NDC1 55706 0 0 11
GSE74703 NDC1 55706 4 1 31
GSE74704 NDC1 55706 2 0 18
TCGA NDC1 55706 10 18 68

Total number of gains: 48; Total number of losses: 35; Total Number of normals: 405.  

 

Somatic mutations of NDC1:

 

Generating mutation plots.

 

Highly correlated genes for NDC1:

 

Showing top 20/1517 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NDC1CDC200.79518811011
NDC1KIF2C0.78818911010
NDC1CDCA80.77574111010
NDC1DLGAP50.774211011
NDC1RACGAP10.767492909
NDC1CDCA50.766096707
NDC1STIL0.76530911011
NDC1CDCA20.757832505
NDC1CSE1L0.753873909
NDC1CDKN30.75292411011
NDC1MRPL420.751006807
NDC1ORC10.74885710010
NDC1NUP370.74447811011
NDC1TPX20.74376111011
NDC1UBE2T0.740265707
NDC1ATAD20.73916511011
NDC1CDK10.73708911011
NDC1CKS1B0.73671111011
NDC1CHEK10.73559511011
NDC1RAD51AP10.73534611011

For details and further investigation, click here