| Full name: mitochondrial ribosomal protein L43 | Alias Symbol: bMRP36a | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 84545 | HGNC ID: HGNC:14517 | Ensembl Gene: ENSG00000055950 | OMIM ID: 611848 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPL43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL43 | 84545 | 224332_s_at | 0.0023 | 0.9959 | |
| GSE26886 | MRPL43 | 84545 | 224332_s_at | 0.8543 | 0.0000 | |
| GSE45670 | MRPL43 | 84545 | 224332_s_at | -0.2853 | 0.0463 | |
| GSE53622 | MRPL43 | 84545 | 80703 | 0.0266 | 0.7189 | |
| GSE53624 | MRPL43 | 84545 | 80703 | 0.0577 | 0.3494 | |
| GSE63941 | MRPL43 | 84545 | 224332_s_at | -0.1744 | 0.6729 | |
| GSE77861 | MRPL43 | 84545 | 230027_s_at | -0.2171 | 0.4803 | |
| GSE97050 | MRPL43 | 84545 | A_33_P3263824 | -0.1117 | 0.6300 | |
| SRP007169 | MRPL43 | 84545 | RNAseq | -0.6457 | 0.1279 | |
| SRP008496 | MRPL43 | 84545 | RNAseq | -0.7108 | 0.0048 | |
| SRP064894 | MRPL43 | 84545 | RNAseq | -0.0618 | 0.8082 | |
| SRP133303 | MRPL43 | 84545 | RNAseq | -0.1962 | 0.0693 | |
| SRP159526 | MRPL43 | 84545 | RNAseq | -0.2322 | 0.2726 | |
| SRP193095 | MRPL43 | 84545 | RNAseq | -0.2118 | 0.0173 | |
| SRP219564 | MRPL43 | 84545 | RNAseq | -0.2597 | 0.4094 | |
| TCGA | MRPL43 | 84545 | RNAseq | -0.0596 | 0.2466 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL43 | 84545 | 1 | 8 | 21 | |
| GSE20123 | MRPL43 | 84545 | 1 | 7 | 22 | |
| GSE43470 | MRPL43 | 84545 | 0 | 8 | 35 | |
| GSE46452 | MRPL43 | 84545 | 0 | 11 | 48 | |
| GSE47630 | MRPL43 | 84545 | 2 | 14 | 24 | |
| GSE54993 | MRPL43 | 84545 | 8 | 0 | 62 | |
| GSE54994 | MRPL43 | 84545 | 1 | 12 | 40 | |
| GSE60625 | MRPL43 | 84545 | 0 | 0 | 11 | |
| GSE74703 | MRPL43 | 84545 | 0 | 5 | 31 | |
| GSE74704 | MRPL43 | 84545 | 0 | 4 | 16 | |
| TCGA | MRPL43 | 84545 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 97; Total Number of normals: 373.
Somatic mutations of MRPL43:
Generating mutation plots.
Highly correlated genes for MRPL43:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL43 | TSNARE1 | 0.751803 | 3 | 0 | 3 |
| MRPL43 | RPL22 | 0.704808 | 4 | 0 | 4 |
| MRPL43 | EIF3G | 0.699306 | 3 | 0 | 3 |
| MRPL43 | CHCHD6 | 0.69569 | 3 | 0 | 3 |
| MRPL43 | FOXA1 | 0.694775 | 3 | 0 | 3 |
| MRPL43 | WDR83OS | 0.676346 | 4 | 0 | 3 |
| MRPL43 | FAF1 | 0.675775 | 4 | 0 | 3 |
| MRPL43 | PDHA1 | 0.659915 | 3 | 0 | 3 |
| MRPL43 | SYCE1L | 0.65933 | 3 | 0 | 3 |
| MRPL43 | CD151 | 0.654079 | 3 | 0 | 3 |
| MRPL43 | CITED1 | 0.648449 | 3 | 0 | 3 |
| MRPL43 | HOXB5 | 0.647113 | 3 | 0 | 3 |
| MRPL43 | REPS2 | 0.646529 | 4 | 0 | 4 |
| MRPL43 | BEND7 | 0.640234 | 4 | 0 | 3 |
| MRPL43 | POLR2J | 0.625423 | 3 | 0 | 3 |
| MRPL43 | BMPR1B | 0.623517 | 3 | 0 | 3 |
| MRPL43 | YBX1 | 0.619636 | 4 | 0 | 3 |
| MRPL43 | TSR3 | 0.618458 | 3 | 0 | 3 |
| MRPL43 | CHCHD5 | 0.618155 | 3 | 0 | 3 |
| MRPL43 | FERD3L | 0.612289 | 3 | 0 | 3 |
For details and further investigation, click here
