| Full name: family with sequence similarity 117 member A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 81558 | HGNC ID: HGNC:24179 | Ensembl Gene: ENSG00000121104 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM117A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM117A | 81558 | 221249_s_at | -0.2994 | 0.6044 | |
| GSE20347 | FAM117A | 81558 | 221249_s_at | 0.2904 | 0.2697 | |
| GSE23400 | FAM117A | 81558 | 221249_s_at | -0.0162 | 0.8926 | |
| GSE26886 | FAM117A | 81558 | 221249_s_at | 0.6748 | 0.0290 | |
| GSE29001 | FAM117A | 81558 | 221249_s_at | 0.1198 | 0.6994 | |
| GSE38129 | FAM117A | 81558 | 221249_s_at | -0.0995 | 0.7148 | |
| GSE45670 | FAM117A | 81558 | 221249_s_at | -0.7180 | 0.0049 | |
| GSE53622 | FAM117A | 81558 | 44276 | -0.3770 | 0.0116 | |
| GSE53624 | FAM117A | 81558 | 44276 | -0.2119 | 0.0192 | |
| GSE63941 | FAM117A | 81558 | 221249_s_at | 1.2488 | 0.0885 | |
| GSE77861 | FAM117A | 81558 | 221249_s_at | 0.0256 | 0.9484 | |
| GSE97050 | FAM117A | 81558 | A_23_P78053 | -0.6603 | 0.2139 | |
| SRP007169 | FAM117A | 81558 | RNAseq | -0.3834 | 0.3696 | |
| SRP008496 | FAM117A | 81558 | RNAseq | -0.1350 | 0.6947 | |
| SRP064894 | FAM117A | 81558 | RNAseq | -0.1952 | 0.1243 | |
| SRP133303 | FAM117A | 81558 | RNAseq | -0.6598 | 0.0008 | |
| SRP159526 | FAM117A | 81558 | RNAseq | 0.3978 | 0.3617 | |
| SRP193095 | FAM117A | 81558 | RNAseq | 0.1133 | 0.5087 | |
| SRP219564 | FAM117A | 81558 | RNAseq | -0.4081 | 0.4150 | |
| TCGA | FAM117A | 81558 | RNAseq | -0.1717 | 0.0983 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM117A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM117A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM117A | 81558 | 6 | 2 | 22 | |
| GSE20123 | FAM117A | 81558 | 6 | 2 | 22 | |
| GSE43470 | FAM117A | 81558 | 3 | 2 | 38 | |
| GSE46452 | FAM117A | 81558 | 32 | 0 | 27 | |
| GSE47630 | FAM117A | 81558 | 9 | 0 | 31 | |
| GSE54993 | FAM117A | 81558 | 2 | 4 | 64 | |
| GSE54994 | FAM117A | 81558 | 10 | 5 | 38 | |
| GSE60625 | FAM117A | 81558 | 4 | 0 | 7 | |
| GSE74703 | FAM117A | 81558 | 3 | 2 | 31 | |
| GSE74704 | FAM117A | 81558 | 4 | 1 | 15 | |
| TCGA | FAM117A | 81558 | 27 | 7 | 62 |
Total number of gains: 106; Total number of losses: 25; Total Number of normals: 357.
Somatic mutations of FAM117A:
Generating mutation plots.
Highly correlated genes for FAM117A:
Showing top 20/590 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM117A | EID3 | 0.776208 | 3 | 0 | 3 |
| FAM117A | AMIGO1 | 0.746626 | 3 | 0 | 3 |
| FAM117A | RIMKLB | 0.729417 | 3 | 0 | 3 |
| FAM117A | EMD | 0.720456 | 3 | 0 | 3 |
| FAM117A | C20orf194 | 0.711468 | 3 | 0 | 3 |
| FAM117A | BVES | 0.707479 | 4 | 0 | 3 |
| FAM117A | CNIH3 | 0.705641 | 3 | 0 | 3 |
| FAM117A | ABRA | 0.698741 | 3 | 0 | 3 |
| FAM117A | PJA1 | 0.697531 | 3 | 0 | 3 |
| FAM117A | CLEC14A | 0.69023 | 4 | 0 | 3 |
| FAM117A | FILIP1 | 0.6873 | 4 | 0 | 3 |
| FAM117A | WDR35 | 0.685272 | 5 | 0 | 4 |
| FAM117A | GRK5 | 0.684827 | 3 | 0 | 3 |
| FAM117A | RASD2 | 0.679774 | 4 | 0 | 3 |
| FAM117A | PNKD | 0.677957 | 4 | 0 | 3 |
| FAM117A | ICA1L | 0.673682 | 4 | 0 | 3 |
| FAM117A | DCHS1 | 0.672632 | 7 | 0 | 6 |
| FAM117A | BCL2 | 0.669408 | 8 | 0 | 8 |
| FAM117A | DTNA | 0.667437 | 4 | 0 | 3 |
| FAM117A | BEND5 | 0.664975 | 9 | 0 | 7 |
For details and further investigation, click here
