| Full name: dystrobrevin alpha | Alias Symbol: D18S892E|DTN|DTN-1|DTN-2|DTN-3|DRP3 | ||
| Type: protein-coding gene | Cytoband: 18q12.1 | ||
| Entrez ID: 1837 | HGNC ID: HGNC:3057 | Ensembl Gene: ENSG00000134769 | OMIM ID: 601239 |
| Drug and gene relationship at DGIdb | |||
Expression of DTNA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DTNA | 1837 | 227084_at | -2.3430 | 0.1343 | |
| GSE20347 | DTNA | 1837 | 210736_x_at | -0.0279 | 0.7384 | |
| GSE23400 | DTNA | 1837 | 210736_x_at | -0.1953 | 0.0000 | |
| GSE26886 | DTNA | 1837 | 210736_x_at | -0.0522 | 0.6240 | |
| GSE29001 | DTNA | 1837 | 211493_x_at | -0.1121 | 0.5051 | |
| GSE38129 | DTNA | 1837 | 210736_x_at | -0.2617 | 0.0024 | |
| GSE45670 | DTNA | 1837 | 227084_at | -2.3711 | 0.0000 | |
| GSE53622 | DTNA | 1837 | 32591 | -0.8507 | 0.0000 | |
| GSE53624 | DTNA | 1837 | 32591 | -0.2283 | 0.0141 | |
| GSE63941 | DTNA | 1837 | 211493_x_at | 0.0566 | 0.8216 | |
| GSE77861 | DTNA | 1837 | 210736_x_at | -0.0565 | 0.4777 | |
| GSE97050 | DTNA | 1837 | A_33_P3371785 | -0.4955 | 0.3240 | |
| SRP007169 | DTNA | 1837 | RNAseq | 3.1406 | 0.0004 | |
| SRP064894 | DTNA | 1837 | RNAseq | -0.4343 | 0.3201 | |
| SRP133303 | DTNA | 1837 | RNAseq | -0.0058 | 0.9911 | |
| SRP159526 | DTNA | 1837 | RNAseq | -0.7598 | 0.3623 | |
| SRP193095 | DTNA | 1837 | RNAseq | 1.6260 | 0.0000 | |
| SRP219564 | DTNA | 1837 | RNAseq | -1.3460 | 0.2132 | |
| TCGA | DTNA | 1837 | RNAseq | -0.6822 | 0.0036 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by DTNA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DTNA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DTNA | 1837 | 2 | 5 | 23 | |
| GSE20123 | DTNA | 1837 | 2 | 6 | 22 | |
| GSE43470 | DTNA | 1837 | 0 | 3 | 40 | |
| GSE46452 | DTNA | 1837 | 1 | 25 | 33 | |
| GSE47630 | DTNA | 1837 | 5 | 20 | 15 | |
| GSE54993 | DTNA | 1837 | 7 | 1 | 62 | |
| GSE54994 | DTNA | 1837 | 1 | 16 | 36 | |
| GSE60625 | DTNA | 1837 | 0 | 4 | 7 | |
| GSE74703 | DTNA | 1837 | 0 | 3 | 33 | |
| GSE74704 | DTNA | 1837 | 1 | 5 | 14 | |
| TCGA | DTNA | 1837 | 15 | 36 | 45 |
Total number of gains: 34; Total number of losses: 124; Total Number of normals: 330.
Somatic mutations of DTNA:
Generating mutation plots.
Highly correlated genes for DTNA:
Showing top 20/1057 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DTNA | RBPMS2 | 0.871129 | 4 | 0 | 4 |
| DTNA | C3orf70 | 0.839427 | 4 | 0 | 4 |
| DTNA | MTURN | 0.832061 | 3 | 0 | 3 |
| DTNA | SORCS1 | 0.825221 | 3 | 0 | 3 |
| DTNA | ANO5 | 0.8208 | 4 | 0 | 4 |
| DTNA | RNF150 | 0.81854 | 4 | 0 | 4 |
| DTNA | SMOC2 | 0.81154 | 4 | 0 | 4 |
| DTNA | MAMDC2 | 0.807696 | 4 | 0 | 4 |
| DTNA | ANGPTL1 | 0.799837 | 4 | 0 | 4 |
| DTNA | RBM24 | 0.795943 | 4 | 0 | 4 |
| DTNA | XKR4 | 0.792706 | 4 | 0 | 4 |
| DTNA | PTCHD1 | 0.785609 | 4 | 0 | 4 |
| DTNA | KCNT2 | 0.783383 | 4 | 0 | 4 |
| DTNA | RSPO3 | 0.78116 | 4 | 0 | 4 |
| DTNA | FBXO30 | 0.780297 | 4 | 0 | 4 |
| DTNA | MAGI2-AS3 | 0.776416 | 3 | 0 | 3 |
| DTNA | SLMAP | 0.770938 | 4 | 0 | 4 |
| DTNA | ADAMTSL1 | 0.770611 | 4 | 0 | 4 |
| DTNA | FIBIN | 0.769812 | 4 | 0 | 4 |
| DTNA | INMT | 0.766228 | 5 | 0 | 4 |
For details and further investigation, click here
