SRSF11

 

Full name: serine and arginine rich splicing factor 11 Alias Symbol: p54|NET2
Type: protein-coding gene Cytoband: 1p31.1
Entrez ID: 9295 HGNC ID: HGNC:10782 Ensembl Gene: ENSG00000116754 OMIM ID: 602010
Screen Evidence:

 

Expression of SRSF11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SRSF11 9295 200686_s_at 0.1039 0.7231
GSE20347 SRSF11 9295 200686_s_at 0.3589 0.0035
GSE23400 SRSF11 9295 200686_s_at 0.2248 0.0052
GSE26886 SRSF11 9295 200686_s_at 0.0977 0.5668
GSE29001 SRSF11 9295 200686_s_at 0.2491 0.1527
GSE38129 SRSF11 9295 200686_s_at 0.2657 0.1308
GSE45670 SRSF11 9295 200686_s_at -0.0462 0.7328
GSE53622 SRSF11 9295 2249 0.4001 0.0000
GSE53624 SRSF11 9295 2249 0.4885 0.0000
GSE63941 SRSF11 9295 200686_s_at -0.2227 0.5364
GSE77861 SRSF11 9295 200686_s_at 0.0918 0.6227
GSE97050 SRSF11 9295 A_33_P3369550 -0.2757 0.2232
SRP007169 SRSF11 9295 RNAseq 0.8332 0.0129
SRP008496 SRSF11 9295 RNAseq 0.8493 0.0000
SRP064894 SRSF11 9295 RNAseq 0.1972 0.3399
SRP133303 SRSF11 9295 RNAseq 0.0549 0.6688
SRP159526 SRSF11 9295 RNAseq -0.2222 0.5804
SRP193095 SRSF11 9295 RNAseq 0.0210 0.8194
SRP219564 SRSF11 9295 RNAseq 0.0458 0.8958

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by SRSF11 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of SRSF11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SRSF11 9295 2 6 22
GSE20123 SRSF11 9295 2 5 23
GSE43470 SRSF11 9295 4 4 35
GSE46452 SRSF11 9295 0 1 58
GSE47630 SRSF11 9295 7 6 27
GSE54993 SRSF11 9295 0 0 70
GSE54994 SRSF11 9295 6 4 43
GSE60625 SRSF11 9295 0 0 11
GSE74703 SRSF11 9295 3 3 30
GSE74704 SRSF11 9295 1 2 17
TCGA SRSF11 9295 8 22 66

Total number of gains: 33; Total number of losses: 53; Total Number of normals: 402.  


 

Somatic mutations of SRSF11:

 

Generating mutation plots.

 

Highly correlated genes for SRSF11:

 

Showing top 20/450 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SRSF11AGTPBP10.771663303
SRSF11BCORL10.767486303
SRSF11ZNF4170.755897303
SRSF11INTS60.754089303
SRSF11RPL27A0.753206303
SRSF11BCL9L0.741805303
SRSF11METTL80.733206303
SRSF11WDR350.728588303
SRSF11CCDC1270.723107303
SRSF11POU2F10.721612505
SRSF11ANAPC40.721408404
SRSF11PNPLA80.716035303
SRSF11ACAD110.713565303
SRSF11PAN20.712008303
SRSF11FAM133B0.711551303
SRSF11BRD80.701989303
SRSF11UBQLN40.700426404
SRSF11VAMP10.691619303
SRSF11WDR270.691372403
SRSF11RB1CC10.690544505

For details and further investigation, click here