| Full name: WD repeat and SOCS box containing 1 | Alias Symbol: DKFZp564A122|DKFZp564B0482|SWIP1 | ||
| Type: protein-coding gene | Cytoband: 17q11.1 | ||
| Entrez ID: 26118 | HGNC ID: HGNC:19221 | Ensembl Gene: ENSG00000109046 | OMIM ID: 610091 |
| Drug and gene relationship at DGIdb | |||
Expression of WSB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WSB1 | 26118 | 201296_s_at | -0.4151 | 0.1365 | |
| GSE20347 | WSB1 | 26118 | 210561_s_at | 0.0004 | 0.9985 | |
| GSE23400 | WSB1 | 26118 | 201296_s_at | -0.0589 | 0.5199 | |
| GSE26886 | WSB1 | 26118 | 201296_s_at | 0.0206 | 0.9384 | |
| GSE29001 | WSB1 | 26118 | 201296_s_at | -0.1711 | 0.4400 | |
| GSE38129 | WSB1 | 26118 | 201296_s_at | 0.0905 | 0.5364 | |
| GSE45670 | WSB1 | 26118 | 210561_s_at | -0.2106 | 0.1372 | |
| GSE53622 | WSB1 | 26118 | 7386 | 0.2479 | 0.0004 | |
| GSE53624 | WSB1 | 26118 | 7386 | 0.1734 | 0.0126 | |
| GSE63941 | WSB1 | 26118 | 201296_s_at | -0.1622 | 0.7922 | |
| GSE77861 | WSB1 | 26118 | 201296_s_at | 0.6879 | 0.0710 | |
| GSE97050 | WSB1 | 26118 | A_23_P4353 | -0.1178 | 0.5613 | |
| SRP007169 | WSB1 | 26118 | RNAseq | 0.8815 | 0.0551 | |
| SRP008496 | WSB1 | 26118 | RNAseq | 0.7228 | 0.0053 | |
| SRP064894 | WSB1 | 26118 | RNAseq | -0.2481 | 0.3594 | |
| SRP133303 | WSB1 | 26118 | RNAseq | 0.2616 | 0.1058 | |
| SRP159526 | WSB1 | 26118 | RNAseq | -0.7093 | 0.0023 | |
| SRP193095 | WSB1 | 26118 | RNAseq | 0.0933 | 0.3945 | |
| SRP219564 | WSB1 | 26118 | RNAseq | -0.4350 | 0.2915 | |
| TCGA | WSB1 | 26118 | RNAseq | -0.1661 | 0.0066 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WSB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WSB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WSB1 | 26118 | 7 | 3 | 20 | |
| GSE20123 | WSB1 | 26118 | 6 | 3 | 21 | |
| GSE43470 | WSB1 | 26118 | 0 | 1 | 42 | |
| GSE46452 | WSB1 | 26118 | 33 | 1 | 25 | |
| GSE47630 | WSB1 | 26118 | 7 | 1 | 32 | |
| GSE54993 | WSB1 | 26118 | 2 | 3 | 65 | |
| GSE54994 | WSB1 | 26118 | 7 | 6 | 40 | |
| GSE60625 | WSB1 | 26118 | 4 | 0 | 7 | |
| GSE74703 | WSB1 | 26118 | 0 | 1 | 35 | |
| GSE74704 | WSB1 | 26118 | 5 | 1 | 14 | |
| TCGA | WSB1 | 26118 | 21 | 11 | 64 |
Total number of gains: 92; Total number of losses: 31; Total Number of normals: 365.
Somatic mutations of WSB1:
Generating mutation plots.
Highly correlated genes for WSB1:
Showing top 20/90 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WSB1 | TUBB2A | 0.807994 | 3 | 0 | 3 |
| WSB1 | SRSF5 | 0.737809 | 4 | 0 | 4 |
| WSB1 | FAM133B | 0.708064 | 3 | 0 | 3 |
| WSB1 | CLASP1 | 0.691785 | 4 | 0 | 4 |
| WSB1 | KIAA0895L | 0.691109 | 4 | 0 | 3 |
| WSB1 | MKNK1 | 0.68458 | 3 | 0 | 3 |
| WSB1 | JUN | 0.682386 | 3 | 0 | 3 |
| WSB1 | GNB4 | 0.678354 | 3 | 0 | 3 |
| WSB1 | SPAG9 | 0.674277 | 4 | 0 | 3 |
| WSB1 | EHD1 | 0.67321 | 4 | 0 | 3 |
| WSB1 | ELFN1 | 0.672386 | 3 | 0 | 3 |
| WSB1 | RND1 | 0.66365 | 4 | 0 | 3 |
| WSB1 | HBEGF | 0.663218 | 3 | 0 | 3 |
| WSB1 | EEF1A2 | 0.661581 | 3 | 0 | 3 |
| WSB1 | ZNF346 | 0.660393 | 4 | 0 | 3 |
| WSB1 | CLK3 | 0.660134 | 4 | 0 | 3 |
| WSB1 | LRRC20 | 0.658525 | 3 | 0 | 3 |
| WSB1 | ANKRD37 | 0.656395 | 3 | 0 | 3 |
| WSB1 | MAFF | 0.65537 | 4 | 0 | 3 |
| WSB1 | KCNJ10 | 0.654856 | 3 | 0 | 3 |
For details and further investigation, click here
