| Full name: ventral anterior homeobox 2 | Alias Symbol: DRES93 | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 25806 | HGNC ID: HGNC:12661 | Ensembl Gene: ENSG00000116035 | OMIM ID: 604295 |
| Drug and gene relationship at DGIdb | |||
Expression of VAX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VAX2 | 25806 | 220443_s_at | 0.3618 | 0.3265 | |
| GSE20347 | VAX2 | 25806 | 220443_s_at | 0.0241 | 0.8280 | |
| GSE23400 | VAX2 | 25806 | 220443_s_at | -0.2275 | 0.0000 | |
| GSE26886 | VAX2 | 25806 | 220443_s_at | 0.4987 | 0.0125 | |
| GSE29001 | VAX2 | 25806 | 220443_s_at | -0.0503 | 0.7736 | |
| GSE38129 | VAX2 | 25806 | 220443_s_at | 0.2307 | 0.0101 | |
| GSE45670 | VAX2 | 25806 | 220443_s_at | 0.0985 | 0.2880 | |
| GSE53622 | VAX2 | 25806 | 19018 | 0.0718 | 0.5342 | |
| GSE53624 | VAX2 | 25806 | 19018 | 0.1193 | 0.4212 | |
| GSE63941 | VAX2 | 25806 | 220443_s_at | 0.0798 | 0.8731 | |
| GSE77861 | VAX2 | 25806 | 220443_s_at | -0.0914 | 0.3317 | |
| GSE97050 | VAX2 | 25806 | A_33_P3267562 | -0.2097 | 0.5076 | |
| SRP133303 | VAX2 | 25806 | RNAseq | 1.8271 | 0.0000 | |
| SRP219564 | VAX2 | 25806 | RNAseq | 2.0691 | 0.0006 | |
| TCGA | VAX2 | 25806 | RNAseq | 2.0517 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by VAX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VAX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VAX2 | 25806 | 11 | 1 | 18 | |
| GSE20123 | VAX2 | 25806 | 11 | 1 | 18 | |
| GSE43470 | VAX2 | 25806 | 3 | 0 | 40 | |
| GSE46452 | VAX2 | 25806 | 2 | 3 | 54 | |
| GSE47630 | VAX2 | 25806 | 7 | 0 | 33 | |
| GSE54993 | VAX2 | 25806 | 0 | 6 | 64 | |
| GSE54994 | VAX2 | 25806 | 11 | 0 | 42 | |
| GSE60625 | VAX2 | 25806 | 0 | 3 | 8 | |
| GSE74703 | VAX2 | 25806 | 3 | 0 | 33 | |
| GSE74704 | VAX2 | 25806 | 9 | 0 | 11 | |
| TCGA | VAX2 | 25806 | 37 | 2 | 57 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of VAX2:
Generating mutation plots.
Highly correlated genes for VAX2:
Showing top 20/377 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VAX2 | KIR3DL2 | 0.786795 | 3 | 0 | 3 |
| VAX2 | ALG11 | 0.782326 | 3 | 0 | 3 |
| VAX2 | KRTAP10-9 | 0.770708 | 3 | 0 | 3 |
| VAX2 | TIGD1 | 0.767047 | 5 | 0 | 5 |
| VAX2 | C12orf50 | 0.761902 | 3 | 0 | 3 |
| VAX2 | TMEM65 | 0.76052 | 3 | 0 | 3 |
| VAX2 | SFTPA2 | 0.756279 | 3 | 0 | 3 |
| VAX2 | OR2T33 | 0.748737 | 4 | 0 | 4 |
| VAX2 | KRTAP10-4 | 0.740934 | 3 | 0 | 3 |
| VAX2 | KRTAP12-2 | 0.739396 | 4 | 0 | 3 |
| VAX2 | KCNJ9 | 0.734828 | 4 | 0 | 4 |
| VAX2 | OR2AT4 | 0.734383 | 3 | 0 | 3 |
| VAX2 | SPEG | 0.728267 | 4 | 0 | 3 |
| VAX2 | SLC26A5 | 0.72784 | 4 | 0 | 4 |
| VAX2 | ZNF445 | 0.722899 | 4 | 0 | 4 |
| VAX2 | VSIG8 | 0.716937 | 3 | 0 | 3 |
| VAX2 | ARL17A | 0.710864 | 3 | 0 | 3 |
| VAX2 | LRP5L | 0.710572 | 3 | 0 | 3 |
| VAX2 | DLGAP2-AS1 | 0.707966 | 3 | 0 | 3 |
| VAX2 | MED24 | 0.703338 | 3 | 0 | 3 |
For details and further investigation, click here
