| Full name: family with sequence similarity 186 member B | Alias Symbol: DKFZP434J0113 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 84070 | HGNC ID: HGNC:25296 | Ensembl Gene: ENSG00000135436 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM186B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM186B | 84070 | 224039_at | -0.0429 | 0.9044 | |
| GSE26886 | FAM186B | 84070 | 224039_at | 0.2868 | 0.1043 | |
| GSE45670 | FAM186B | 84070 | 224039_at | -0.0086 | 0.9503 | |
| GSE53622 | FAM186B | 84070 | 5500 | 0.0128 | 0.9378 | |
| GSE53624 | FAM186B | 84070 | 5500 | 0.0530 | 0.6550 | |
| GSE63941 | FAM186B | 84070 | 224039_at | 0.2474 | 0.1665 | |
| GSE77861 | FAM186B | 84070 | 224039_at | -0.1452 | 0.2804 | |
| GSE97050 | FAM186B | 84070 | A_23_P25445 | -0.3621 | 0.4348 | |
| SRP133303 | FAM186B | 84070 | RNAseq | 0.0317 | 0.9109 | |
| SRP159526 | FAM186B | 84070 | RNAseq | 0.7129 | 0.2288 | |
| SRP219564 | FAM186B | 84070 | RNAseq | 0.4635 | 0.2586 | |
| TCGA | FAM186B | 84070 | RNAseq | 0.0857 | 0.6378 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM186B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM186B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM186B | 84070 | 7 | 1 | 22 | |
| GSE20123 | FAM186B | 84070 | 7 | 1 | 22 | |
| GSE43470 | FAM186B | 84070 | 3 | 1 | 39 | |
| GSE46452 | FAM186B | 84070 | 8 | 1 | 50 | |
| GSE47630 | FAM186B | 84070 | 11 | 2 | 27 | |
| GSE54993 | FAM186B | 84070 | 0 | 5 | 65 | |
| GSE54994 | FAM186B | 84070 | 4 | 1 | 48 | |
| GSE60625 | FAM186B | 84070 | 0 | 0 | 11 | |
| GSE74703 | FAM186B | 84070 | 3 | 1 | 32 | |
| GSE74704 | FAM186B | 84070 | 5 | 1 | 14 | |
| TCGA | FAM186B | 84070 | 16 | 11 | 69 |
Total number of gains: 64; Total number of losses: 25; Total Number of normals: 399.
Somatic mutations of FAM186B:
Generating mutation plots.
Highly correlated genes for FAM186B:
Showing top 20/213 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM186B | SMIM6 | 0.727214 | 3 | 0 | 3 |
| FAM186B | LIF | 0.725646 | 3 | 0 | 3 |
| FAM186B | KLHL25 | 0.724021 | 3 | 0 | 3 |
| FAM186B | PABPN1L | 0.718165 | 3 | 0 | 3 |
| FAM186B | SCUBE1 | 0.70309 | 4 | 0 | 4 |
| FAM186B | FGF17 | 0.694499 | 3 | 0 | 3 |
| FAM186B | KRTAP13-1 | 0.681165 | 3 | 0 | 3 |
| FAM186B | SCN2B | 0.679032 | 3 | 0 | 3 |
| FAM186B | UGT3A1 | 0.676297 | 3 | 0 | 3 |
| FAM186B | SIGLEC8 | 0.676221 | 3 | 0 | 3 |
| FAM186B | ZNF454 | 0.668277 | 3 | 0 | 3 |
| FAM186B | CDR1 | 0.667352 | 3 | 0 | 3 |
| FAM186B | LINC00474 | 0.663388 | 4 | 0 | 4 |
| FAM186B | TMEM198 | 0.663227 | 3 | 0 | 3 |
| FAM186B | GPR173 | 0.662629 | 3 | 0 | 3 |
| FAM186B | P2RY4 | 0.662399 | 3 | 0 | 3 |
| FAM186B | TMEM151B | 0.658013 | 3 | 0 | 3 |
| FAM186B | MRGPRG-AS1 | 0.657656 | 3 | 0 | 3 |
| FAM186B | TACR2 | 0.657468 | 3 | 0 | 3 |
| FAM186B | C1orf61 | 0.655685 | 3 | 0 | 3 |
For details and further investigation, click here
