| Full name: transmembrane protein 198 | Alias Symbol: MGC99813|TMEM198A | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 130612 | HGNC ID: HGNC:33704 | Ensembl Gene: ENSG00000188760 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM198:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM198 | 130612 | 227890_at | -0.1436 | 0.6582 | |
| GSE26886 | TMEM198 | 130612 | 242782_x_at | 0.3521 | 0.0044 | |
| GSE45670 | TMEM198 | 130612 | 227890_at | -0.1879 | 0.1514 | |
| GSE53622 | TMEM198 | 130612 | 94510 | 0.5108 | 0.0057 | |
| GSE53624 | TMEM198 | 130612 | 94510 | 0.6370 | 0.0000 | |
| GSE63941 | TMEM198 | 130612 | 227890_at | -0.2666 | 0.3646 | |
| GSE77861 | TMEM198 | 130612 | 227890_at | -0.1888 | 0.2148 | |
| GSE97050 | TMEM198 | 130612 | A_24_P822704 | 0.2475 | 0.2652 | |
| SRP064894 | TMEM198 | 130612 | RNAseq | 0.5593 | 0.0312 | |
| SRP133303 | TMEM198 | 130612 | RNAseq | 0.0692 | 0.8560 | |
| SRP159526 | TMEM198 | 130612 | RNAseq | 0.8920 | 0.0389 | |
| SRP219564 | TMEM198 | 130612 | RNAseq | 0.4911 | 0.3504 | |
| TCGA | TMEM198 | 130612 | RNAseq | -0.1458 | 0.3300 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM198 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM198:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM198 | 130612 | 2 | 14 | 14 | |
| GSE20123 | TMEM198 | 130612 | 2 | 13 | 15 | |
| GSE43470 | TMEM198 | 130612 | 1 | 6 | 36 | |
| GSE46452 | TMEM198 | 130612 | 0 | 5 | 54 | |
| GSE47630 | TMEM198 | 130612 | 4 | 5 | 31 | |
| GSE54993 | TMEM198 | 130612 | 1 | 2 | 67 | |
| GSE54994 | TMEM198 | 130612 | 8 | 9 | 36 | |
| GSE60625 | TMEM198 | 130612 | 0 | 3 | 8 | |
| GSE74703 | TMEM198 | 130612 | 1 | 5 | 30 | |
| GSE74704 | TMEM198 | 130612 | 2 | 7 | 11 | |
| TCGA | TMEM198 | 130612 | 13 | 25 | 58 |
Total number of gains: 34; Total number of losses: 94; Total Number of normals: 360.
Somatic mutations of TMEM198:
Generating mutation plots.
Highly correlated genes for TMEM198:
Showing top 20/72 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM198 | DNAJC5B | 0.718509 | 3 | 0 | 3 |
| TMEM198 | ASIC2 | 0.682062 | 3 | 0 | 3 |
| TMEM198 | OPTC | 0.669329 | 3 | 0 | 3 |
| TMEM198 | C2orf81 | 0.667945 | 3 | 0 | 3 |
| TMEM198 | FAM186B | 0.663227 | 3 | 0 | 3 |
| TMEM198 | KAT8 | 0.662815 | 3 | 0 | 3 |
| TMEM198 | THAP3 | 0.65825 | 3 | 0 | 3 |
| TMEM198 | ITGA2B | 0.650711 | 3 | 0 | 3 |
| TMEM198 | GPR17 | 0.645389 | 3 | 0 | 3 |
| TMEM198 | SLC8A3 | 0.641365 | 3 | 0 | 3 |
| TMEM198 | KCNK9 | 0.640158 | 3 | 0 | 3 |
| TMEM198 | FOXJ1 | 0.638429 | 3 | 0 | 3 |
| TMEM198 | ATXN7L2 | 0.637835 | 3 | 0 | 3 |
| TMEM198 | CLDN14 | 0.635473 | 4 | 0 | 3 |
| TMEM198 | FAHD2A | 0.631478 | 4 | 0 | 3 |
| TMEM198 | TMEM59L | 0.630939 | 4 | 0 | 3 |
| TMEM198 | PIFO | 0.622027 | 3 | 0 | 3 |
| TMEM198 | NRIP2 | 0.616079 | 3 | 0 | 3 |
| TMEM198 | CARNS1 | 0.613811 | 3 | 0 | 3 |
| TMEM198 | FUT10 | 0.611963 | 4 | 0 | 3 |
For details and further investigation, click here
