| Full name: UDP glycosyltransferase family 3 member A1 | Alias Symbol: FLJ34658 | ||
| Type: protein-coding gene | Cytoband: 5p13.2 | ||
| Entrez ID: 133688 | HGNC ID: HGNC:26625 | Ensembl Gene: ENSG00000145626 | OMIM ID: 616383 |
| Drug and gene relationship at DGIdb | |||
Expression of UGT3A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UGT3A1 | 133688 | 237572_at | -0.0194 | 0.9518 | |
| GSE26886 | UGT3A1 | 133688 | 235904_at | -0.1299 | 0.3156 | |
| GSE45670 | UGT3A1 | 133688 | 237572_at | 0.1216 | 0.2478 | |
| GSE53622 | UGT3A1 | 133688 | 76958 | 0.4264 | 0.0250 | |
| GSE53624 | UGT3A1 | 133688 | 76958 | 0.5663 | 0.0016 | |
| GSE63941 | UGT3A1 | 133688 | 235904_at | 0.0831 | 0.6529 | |
| GSE77861 | UGT3A1 | 133688 | 235904_at | -0.0303 | 0.7784 | |
| GSE97050 | UGT3A1 | 133688 | A_23_P122144 | 0.0197 | 0.9341 | |
| SRP133303 | UGT3A1 | 133688 | RNAseq | 0.0261 | 0.9093 | |
| TCGA | UGT3A1 | 133688 | RNAseq | 3.1649 | 0.0627 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UGT3A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UGT3A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UGT3A1 | 133688 | 10 | 0 | 20 | |
| GSE20123 | UGT3A1 | 133688 | 10 | 0 | 20 | |
| GSE43470 | UGT3A1 | 133688 | 17 | 0 | 26 | |
| GSE46452 | UGT3A1 | 133688 | 5 | 22 | 32 | |
| GSE47630 | UGT3A1 | 133688 | 6 | 12 | 22 | |
| GSE54993 | UGT3A1 | 133688 | 5 | 4 | 61 | |
| GSE54994 | UGT3A1 | 133688 | 26 | 2 | 25 | |
| GSE60625 | UGT3A1 | 133688 | 0 | 0 | 11 | |
| GSE74703 | UGT3A1 | 133688 | 13 | 0 | 23 | |
| GSE74704 | UGT3A1 | 133688 | 9 | 0 | 11 | |
| TCGA | UGT3A1 | 133688 | 52 | 6 | 38 |
Total number of gains: 153; Total number of losses: 46; Total Number of normals: 289.
Somatic mutations of UGT3A1:
Generating mutation plots.
Highly correlated genes for UGT3A1:
Showing top 20/118 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UGT3A1 | DEFB121 | 0.778384 | 3 | 0 | 3 |
| UGT3A1 | CLEC4D | 0.742782 | 3 | 0 | 3 |
| UGT3A1 | TMEM105 | 0.733566 | 3 | 0 | 3 |
| UGT3A1 | PRAMEF12 | 0.713511 | 3 | 0 | 3 |
| UGT3A1 | SPINT3 | 0.707549 | 3 | 0 | 3 |
| UGT3A1 | FAM124B | 0.706005 | 4 | 0 | 4 |
| UGT3A1 | GPHA2 | 0.696674 | 3 | 0 | 3 |
| UGT3A1 | DNAJC5B | 0.690553 | 3 | 0 | 3 |
| UGT3A1 | TNN | 0.690409 | 3 | 0 | 3 |
| UGT3A1 | IL9R | 0.689677 | 4 | 0 | 3 |
| UGT3A1 | CLEC1B | 0.686113 | 3 | 0 | 3 |
| UGT3A1 | NCR3 | 0.684152 | 3 | 0 | 3 |
| UGT3A1 | ST8SIA3 | 0.679223 | 5 | 0 | 4 |
| UGT3A1 | SMOC1 | 0.676806 | 4 | 0 | 3 |
| UGT3A1 | FAM186B | 0.676297 | 3 | 0 | 3 |
| UGT3A1 | ADRA1A | 0.667271 | 3 | 0 | 3 |
| UGT3A1 | PKD2L1 | 0.665632 | 4 | 0 | 4 |
| UGT3A1 | PAX2 | 0.663883 | 4 | 0 | 4 |
| UGT3A1 | PGLYRP1 | 0.660412 | 3 | 0 | 3 |
| UGT3A1 | ADH6 | 0.660318 | 3 | 0 | 3 |
For details and further investigation, click here
