| Full name: family with sequence similarity 78 member B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q24.1 | ||
| Entrez ID: 149297 | HGNC ID: HGNC:13495 | Ensembl Gene: ENSG00000188859 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM78B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM78B | 149297 | 1558113_at | -0.2505 | 0.3417 | |
| GSE26886 | FAM78B | 149297 | 1558113_at | -0.2585 | 0.0353 | |
| GSE45670 | FAM78B | 149297 | 1558113_at | 0.1329 | 0.2014 | |
| GSE53622 | FAM78B | 149297 | 55572 | -0.1366 | 0.0997 | |
| GSE53624 | FAM78B | 149297 | 72056 | 0.0645 | 0.6563 | |
| GSE63941 | FAM78B | 149297 | 1558113_at | 0.0172 | 0.9238 | |
| GSE77861 | FAM78B | 149297 | 1558113_at | 0.0087 | 0.9146 | |
| GSE97050 | FAM78B | 149297 | A_33_P3244104 | -0.1967 | 0.5127 | |
| SRP064894 | FAM78B | 149297 | RNAseq | 0.5611 | 0.1508 | |
| SRP133303 | FAM78B | 149297 | RNAseq | -0.2469 | 0.3092 | |
| SRP159526 | FAM78B | 149297 | RNAseq | -0.1391 | 0.7907 | |
| SRP219564 | FAM78B | 149297 | RNAseq | 0.5041 | 0.4061 | |
| TCGA | FAM78B | 149297 | RNAseq | -0.2124 | 0.2799 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM78B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM78B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM78B | 149297 | 10 | 2 | 18 | |
| GSE20123 | FAM78B | 149297 | 10 | 2 | 18 | |
| GSE43470 | FAM78B | 149297 | 7 | 2 | 34 | |
| GSE46452 | FAM78B | 149297 | 2 | 1 | 56 | |
| GSE47630 | FAM78B | 149297 | 14 | 0 | 26 | |
| GSE54993 | FAM78B | 149297 | 0 | 5 | 65 | |
| GSE54994 | FAM78B | 149297 | 16 | 0 | 37 | |
| GSE60625 | FAM78B | 149297 | 0 | 0 | 11 | |
| GSE74703 | FAM78B | 149297 | 7 | 2 | 27 | |
| GSE74704 | FAM78B | 149297 | 4 | 1 | 15 | |
| TCGA | FAM78B | 149297 | 44 | 3 | 49 |
Total number of gains: 114; Total number of losses: 18; Total Number of normals: 356.
Somatic mutations of FAM78B:
Generating mutation plots.
Highly correlated genes for FAM78B:
Showing top 20/72 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM78B | GP9 | 0.724788 | 3 | 0 | 3 |
| FAM78B | TUBA8 | 0.671901 | 3 | 0 | 3 |
| FAM78B | STAB2 | 0.670757 | 3 | 0 | 3 |
| FAM78B | SLC25A48 | 0.649498 | 3 | 0 | 3 |
| FAM78B | MATN1 | 0.62453 | 3 | 0 | 3 |
| FAM78B | OR4D2 | 0.621811 | 5 | 0 | 4 |
| FAM78B | ESPNL | 0.620693 | 3 | 0 | 3 |
| FAM78B | SLC5A10 | 0.618092 | 4 | 0 | 3 |
| FAM78B | SLC22A2 | 0.617391 | 4 | 0 | 4 |
| FAM78B | SLC10A1 | 0.617347 | 5 | 0 | 5 |
| FAM78B | DNASE1 | 0.615305 | 4 | 0 | 4 |
| FAM78B | INO80C | 0.612152 | 3 | 0 | 3 |
| FAM78B | LINC01103 | 0.608783 | 4 | 0 | 3 |
| FAM78B | SPEF2 | 0.604533 | 3 | 0 | 3 |
| FAM78B | SHISA9 | 0.604202 | 4 | 0 | 3 |
| FAM78B | PFKFB1 | 0.603854 | 3 | 0 | 3 |
| FAM78B | CLEC1B | 0.601692 | 4 | 0 | 3 |
| FAM78B | TULP2 | 0.600769 | 3 | 0 | 3 |
| FAM78B | DPEP3 | 0.600494 | 3 | 0 | 3 |
| FAM78B | TMEM86A | 0.598227 | 4 | 0 | 3 |
For details and further investigation, click here
