STAB2

 

Full name: stabilin 2 Alias Symbol: DKFZP434E0321|FELL|STAB-2|HARE|FEEL-2|SCARH1
Type: protein-coding gene Cytoband: 12q23.3
Entrez ID: 55576 HGNC ID: HGNC:18629 Ensembl Gene: ENSG00000136011 OMIM ID: 608561
Drug and gene relationship at DGIdb

 

Expression of STAB2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 STAB2 55576 220114_s_at -0.3395 0.1651
GSE20347 STAB2 55576 220114_s_at -0.0812 0.4097
GSE23400 STAB2 55576 220114_s_at -0.1128 0.0021
GSE26886 STAB2 55576 237567_at -0.0233 0.8369
GSE29001 STAB2 55576 220114_s_at -0.1245 0.4688
GSE38129 STAB2 55576 220114_s_at -0.3238 0.0028
GSE45670 STAB2 55576 220114_s_at -0.1156 0.2386
GSE53622 STAB2 55576 29009 -1.0324 0.0000
GSE53624 STAB2 55576 29009 -0.6675 0.0000
GSE63941 STAB2 55576 220114_s_at 0.3421 0.0297
GSE77861 STAB2 55576 237567_at -0.0213 0.8423
GSE97050 STAB2 55576 A_23_P162607 -0.1675 0.6132
SRP133303 STAB2 55576 RNAseq -1.3203 0.0001
SRP159526 STAB2 55576 RNAseq -0.3311 0.4894
SRP219564 STAB2 55576 RNAseq -1.1868 0.0375
TCGA STAB2 55576 RNAseq -1.2802 0.0234

Upregulated datasets: 0; Downregulated datasets: 4.  


 

Survival by STAB2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of STAB2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 STAB2 55576 3 2 25
GSE20123 STAB2 55576 3 2 25
GSE43470 STAB2 55576 2 0 41
GSE46452 STAB2 55576 9 1 49
GSE47630 STAB2 55576 9 1 30
GSE54993 STAB2 55576 0 5 65
GSE54994 STAB2 55576 4 2 47
GSE60625 STAB2 55576 0 0 11
GSE74703 STAB2 55576 2 0 34
GSE74704 STAB2 55576 1 2 17
TCGA STAB2 55576 19 11 66

Total number of gains: 52; Total number of losses: 26; Total Number of normals: 410.  


 

Somatic mutations of STAB2:

 

Generating mutation plots.

 

Highly correlated genes for STAB2:

 

Showing top 20/631 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
STAB2MYO3A0.679531303
STAB2FAM78B0.670757303
STAB2UBQLN30.659529505
STAB2MAP3K190.653206605
STAB2ASCL30.652189605
STAB2TMPRSS50.648866606
STAB2EDA2R0.645187707
STAB2CSPG50.645073807
STAB2KIR2DS50.641312606
STAB2ADCY10.640723505
STAB2FSTL40.640229505
STAB2PRAF20.636924303
STAB2GPR260.635125403
STAB2REM10.63047706
STAB2EDDM3A0.629986403
STAB2DSCR40.629057404
STAB2IZUMO40.628719403
STAB2GRIN2A0.627727706
STAB2PRODH20.627611807
STAB2CER10.627496605

For details and further investigation, click here