| Full name: transmembrane protein 86A | Alias Symbol: FLJ90119 | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 144110 | HGNC ID: HGNC:26890 | Ensembl Gene: ENSG00000151117 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM86A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM86A | 144110 | 227570_at | -0.0098 | 0.9748 | |
| GSE26886 | TMEM86A | 144110 | 227570_at | -0.0645 | 0.7186 | |
| GSE45670 | TMEM86A | 144110 | 227570_at | -0.0253 | 0.8907 | |
| GSE53622 | TMEM86A | 144110 | 38125 | 0.2695 | 0.0007 | |
| GSE53624 | TMEM86A | 144110 | 38125 | 0.0936 | 0.2427 | |
| GSE63941 | TMEM86A | 144110 | 227570_at | -0.0341 | 0.8825 | |
| GSE77861 | TMEM86A | 144110 | 227570_at | -0.0054 | 0.9715 | |
| GSE97050 | TMEM86A | 144110 | A_32_P66035 | -0.0991 | 0.6597 | |
| SRP007169 | TMEM86A | 144110 | RNAseq | -1.5844 | 0.0427 | |
| SRP064894 | TMEM86A | 144110 | RNAseq | -0.3631 | 0.2292 | |
| SRP133303 | TMEM86A | 144110 | RNAseq | -0.2666 | 0.3279 | |
| SRP159526 | TMEM86A | 144110 | RNAseq | -0.6753 | 0.0835 | |
| SRP193095 | TMEM86A | 144110 | RNAseq | -1.0315 | 0.0001 | |
| SRP219564 | TMEM86A | 144110 | RNAseq | -0.8995 | 0.1413 | |
| TCGA | TMEM86A | 144110 | RNAseq | -0.0865 | 0.5712 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TMEM86A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM86A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM86A | 144110 | 0 | 10 | 20 | |
| GSE20123 | TMEM86A | 144110 | 0 | 10 | 20 | |
| GSE43470 | TMEM86A | 144110 | 1 | 5 | 37 | |
| GSE46452 | TMEM86A | 144110 | 7 | 5 | 47 | |
| GSE47630 | TMEM86A | 144110 | 3 | 10 | 27 | |
| GSE54993 | TMEM86A | 144110 | 3 | 0 | 67 | |
| GSE54994 | TMEM86A | 144110 | 3 | 12 | 38 | |
| GSE60625 | TMEM86A | 144110 | 0 | 0 | 11 | |
| GSE74703 | TMEM86A | 144110 | 1 | 3 | 32 | |
| GSE74704 | TMEM86A | 144110 | 0 | 9 | 11 | |
| TCGA | TMEM86A | 144110 | 11 | 29 | 56 |
Total number of gains: 29; Total number of losses: 93; Total Number of normals: 366.
Somatic mutations of TMEM86A:
Generating mutation plots.
Highly correlated genes for TMEM86A:
Showing top 20/48 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM86A | CLDN14 | 0.731535 | 3 | 0 | 3 |
| TMEM86A | ANGPT4 | 0.70481 | 4 | 0 | 4 |
| TMEM86A | RNF157 | 0.7009 | 3 | 0 | 3 |
| TMEM86A | SLC5A11 | 0.658621 | 3 | 0 | 3 |
| TMEM86A | HCAR3 | 0.656815 | 3 | 0 | 3 |
| TMEM86A | RASSF7 | 0.65538 | 4 | 0 | 4 |
| TMEM86A | OPTC | 0.642483 | 3 | 0 | 3 |
| TMEM86A | LELP1 | 0.640883 | 3 | 0 | 3 |
| TMEM86A | MAP3K10 | 0.636412 | 4 | 0 | 4 |
| TMEM86A | TULP1 | 0.625831 | 3 | 0 | 3 |
| TMEM86A | DNASE1 | 0.62333 | 3 | 0 | 3 |
| TMEM86A | SNAI1 | 0.623075 | 3 | 0 | 3 |
| TMEM86A | RNF39 | 0.61873 | 3 | 0 | 3 |
| TMEM86A | LRCH4 | 0.618443 | 4 | 0 | 3 |
| TMEM86A | LRRIQ3 | 0.613313 | 3 | 0 | 3 |
| TMEM86A | TGM6 | 0.611388 | 4 | 0 | 3 |
| TMEM86A | RAB11FIP4 | 0.611316 | 4 | 0 | 3 |
| TMEM86A | RCOR2 | 0.601458 | 3 | 0 | 3 |
| TMEM86A | SRCIN1 | 0.600664 | 6 | 0 | 3 |
| TMEM86A | FAM78B | 0.598227 | 4 | 0 | 3 |
For details and further investigation, click here
