| Full name: GC-rich promoter binding protein 1 | Alias Symbol: DKFZp761C169|vasculin | ||
| Type: protein-coding gene | Cytoband: 5q11.2 | ||
| Entrez ID: 65056 | HGNC ID: HGNC:29520 | Ensembl Gene: ENSG00000062194 | OMIM ID: 608412 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GPBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPBP1 | 65056 | 223705_s_at | -0.2398 | 0.5655 | |
| GSE26886 | GPBP1 | 65056 | 223705_s_at | -0.1532 | 0.4804 | |
| GSE45670 | GPBP1 | 65056 | 223705_s_at | -0.1788 | 0.3104 | |
| GSE53622 | GPBP1 | 65056 | 31578 | -0.1965 | 0.0030 | |
| GSE53624 | GPBP1 | 65056 | 31578 | -0.2852 | 0.0001 | |
| GSE63941 | GPBP1 | 65056 | 223705_s_at | 0.0248 | 0.9540 | |
| GSE77861 | GPBP1 | 65056 | 223705_s_at | -0.4339 | 0.0220 | |
| GSE97050 | GPBP1 | 65056 | A_23_P364465 | -0.1894 | 0.3879 | |
| SRP007169 | GPBP1 | 65056 | RNAseq | -0.5542 | 0.1501 | |
| SRP008496 | GPBP1 | 65056 | RNAseq | -0.6138 | 0.0031 | |
| SRP064894 | GPBP1 | 65056 | RNAseq | -0.3219 | 0.0114 | |
| SRP133303 | GPBP1 | 65056 | RNAseq | -0.1106 | 0.2845 | |
| SRP159526 | GPBP1 | 65056 | RNAseq | -0.1183 | 0.6002 | |
| SRP193095 | GPBP1 | 65056 | RNAseq | -0.4520 | 0.0000 | |
| SRP219564 | GPBP1 | 65056 | RNAseq | -0.2522 | 0.3153 | |
| TCGA | GPBP1 | 65056 | RNAseq | -0.0590 | 0.1878 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPBP1 | 65056 | 0 | 13 | 17 | |
| GSE20123 | GPBP1 | 65056 | 0 | 13 | 17 | |
| GSE43470 | GPBP1 | 65056 | 1 | 12 | 30 | |
| GSE46452 | GPBP1 | 65056 | 0 | 28 | 31 | |
| GSE47630 | GPBP1 | 65056 | 2 | 16 | 22 | |
| GSE54993 | GPBP1 | 65056 | 8 | 1 | 61 | |
| GSE54994 | GPBP1 | 65056 | 2 | 19 | 32 | |
| GSE60625 | GPBP1 | 65056 | 0 | 0 | 11 | |
| GSE74703 | GPBP1 | 65056 | 1 | 9 | 26 | |
| GSE74704 | GPBP1 | 65056 | 0 | 6 | 14 | |
| TCGA | GPBP1 | 65056 | 7 | 47 | 42 |
Total number of gains: 21; Total number of losses: 164; Total Number of normals: 303.
Somatic mutations of GPBP1:
Generating mutation plots.
Highly correlated genes for GPBP1:
Showing top 20/479 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPBP1 | FBXL3 | 0.861564 | 3 | 0 | 3 |
| GPBP1 | PPIP5K2 | 0.816595 | 3 | 0 | 3 |
| GPBP1 | NCKAP1 | 0.813119 | 3 | 0 | 3 |
| GPBP1 | ZNF33A | 0.80321 | 3 | 0 | 3 |
| GPBP1 | GBE1 | 0.801866 | 3 | 0 | 3 |
| GPBP1 | AP3S1 | 0.801003 | 3 | 0 | 3 |
| GPBP1 | SOS2 | 0.790308 | 3 | 0 | 3 |
| GPBP1 | FNBP4 | 0.786741 | 3 | 0 | 3 |
| GPBP1 | MKRN2 | 0.785757 | 3 | 0 | 3 |
| GPBP1 | TMCO4 | 0.777617 | 3 | 0 | 3 |
| GPBP1 | RNF135 | 0.776097 | 3 | 0 | 3 |
| GPBP1 | ZRANB1 | 0.774686 | 3 | 0 | 3 |
| GPBP1 | DNAJC24 | 0.774581 | 3 | 0 | 3 |
| GPBP1 | HBP1 | 0.773359 | 3 | 0 | 3 |
| GPBP1 | RUFY3 | 0.770389 | 3 | 0 | 3 |
| GPBP1 | OMA1 | 0.766429 | 3 | 0 | 3 |
| GPBP1 | BRWD1 | 0.764865 | 3 | 0 | 3 |
| GPBP1 | PRKAB1 | 0.761732 | 3 | 0 | 3 |
| GPBP1 | PPP4R1 | 0.761011 | 3 | 0 | 3 |
| GPBP1 | RINT1 | 0.760902 | 3 | 0 | 3 |
For details and further investigation, click here
