CMC1

 

Full name: C-X9-C motif containing 1 Alias Symbol: MGC61571
Type: protein-coding gene Cytoband: 3p24.1
Entrez ID: 152100 HGNC ID: HGNC:28783 Ensembl Gene: ENSG00000187118 OMIM ID: 615166
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CMC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CMC1 152100 228283_at -0.0140 0.9735
GSE26886 CMC1 152100 228283_at 0.8037 0.0000
GSE45670 CMC1 152100 228283_at 0.0454 0.7738
GSE53622 CMC1 152100 114249 -0.2687 0.0003
GSE53624 CMC1 152100 114249 -0.1837 0.0208
GSE63941 CMC1 152100 228283_at 0.6228 0.0322
GSE77861 CMC1 152100 228283_at -0.2972 0.1196
GSE97050 CMC1 152100 A_24_P408740 -0.0778 0.7344
SRP007169 CMC1 152100 RNAseq -0.9816 0.0073
SRP008496 CMC1 152100 RNAseq -0.3819 0.1660
SRP064894 CMC1 152100 RNAseq -0.0602 0.7674
SRP133303 CMC1 152100 RNAseq -0.1441 0.3964
SRP159526 CMC1 152100 RNAseq -0.4264 0.1929
SRP193095 CMC1 152100 RNAseq -0.4720 0.0000
SRP219564 CMC1 152100 RNAseq -0.2977 0.4104
TCGA CMC1 152100 RNAseq -0.1513 0.0347

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by CMC1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CMC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CMC1 152100 0 18 12
GSE20123 CMC1 152100 0 18 12
GSE43470 CMC1 152100 0 20 23
GSE46452 CMC1 152100 2 17 40
GSE47630 CMC1 152100 1 24 15
GSE54993 CMC1 152100 6 2 62
GSE54994 CMC1 152100 2 31 20
GSE60625 CMC1 152100 5 0 6
GSE74703 CMC1 152100 0 17 19
GSE74704 CMC1 152100 0 12 8
TCGA CMC1 152100 2 69 25

Total number of gains: 18; Total number of losses: 228; Total Number of normals: 242.  


 

Somatic mutations of CMC1:

 

Generating mutation plots.

 

Highly correlated genes for CMC1:

 

Showing top 20/229 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CMC1ANAPC100.780443303
CMC1GPN30.778377303
CMC1THEM40.777924303
CMC1CKAP50.774376303
CMC1SLC30A50.768646303
CMC1VPS410.766979303
CMC1FMR10.761319303
CMC1MRPL320.748633303
CMC1MRPL190.748169303
CMC1KLHL90.747044303
CMC1CYB5B0.742666303
CMC1TBC1D40.742352303
CMC1VEZT0.738475303
CMC1MAP2K50.735904303
CMC1DPH30.734801303
CMC1ADAT10.734607303
CMC1C17orf750.730418303
CMC1CNOT100.729226404
CMC1MBD10.729088403
CMC1SNRPA10.727968303

For details and further investigation, click here