| Full name: transcriptional adaptor 1 | Alias Symbol: STAF42|ADA1|hADA1|HFI1 | ||
| Type: protein-coding gene | Cytoband: 1q24.1 | ||
| Entrez ID: 117143 | HGNC ID: HGNC:30631 | Ensembl Gene: ENSG00000152382 | OMIM ID: 612763 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TADA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TADA1 | 117143 | 225455_at | 0.1832 | 0.7414 | |
| GSE26886 | TADA1 | 117143 | 225455_at | -0.2436 | 0.4309 | |
| GSE45670 | TADA1 | 117143 | 225455_at | 0.1402 | 0.3942 | |
| GSE53622 | TADA1 | 117143 | 13554 | -0.0285 | 0.6845 | |
| GSE53624 | TADA1 | 117143 | 13554 | -0.0545 | 0.5674 | |
| GSE63941 | TADA1 | 117143 | 225455_at | 0.7821 | 0.0039 | |
| GSE77861 | TADA1 | 117143 | 225455_at | 0.2287 | 0.3117 | |
| GSE97050 | TADA1 | 117143 | A_23_P74344 | 0.0870 | 0.7009 | |
| SRP007169 | TADA1 | 117143 | RNAseq | -0.4209 | 0.3660 | |
| SRP008496 | TADA1 | 117143 | RNAseq | -0.3740 | 0.2585 | |
| SRP064894 | TADA1 | 117143 | RNAseq | -0.2596 | 0.1719 | |
| SRP133303 | TADA1 | 117143 | RNAseq | -0.1270 | 0.4763 | |
| SRP159526 | TADA1 | 117143 | RNAseq | 0.3112 | 0.0482 | |
| SRP193095 | TADA1 | 117143 | RNAseq | -0.1669 | 0.1012 | |
| SRP219564 | TADA1 | 117143 | RNAseq | 0.2765 | 0.4634 | |
| TCGA | TADA1 | 117143 | RNAseq | 0.1349 | 0.0238 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TADA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TADA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TADA1 | 117143 | 11 | 1 | 18 | |
| GSE20123 | TADA1 | 117143 | 11 | 1 | 18 | |
| GSE43470 | TADA1 | 117143 | 7 | 2 | 34 | |
| GSE46452 | TADA1 | 117143 | 2 | 1 | 56 | |
| GSE47630 | TADA1 | 117143 | 14 | 0 | 26 | |
| GSE54993 | TADA1 | 117143 | 0 | 5 | 65 | |
| GSE54994 | TADA1 | 117143 | 16 | 0 | 37 | |
| GSE60625 | TADA1 | 117143 | 0 | 0 | 11 | |
| GSE74703 | TADA1 | 117143 | 7 | 2 | 27 | |
| GSE74704 | TADA1 | 117143 | 5 | 0 | 15 | |
| TCGA | TADA1 | 117143 | 44 | 3 | 49 |
Total number of gains: 117; Total number of losses: 15; Total Number of normals: 356.
Somatic mutations of TADA1:
Generating mutation plots.
Highly correlated genes for TADA1:
Showing top 20/358 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TADA1 | COG3 | 0.808626 | 3 | 0 | 3 |
| TADA1 | DICER1 | 0.802654 | 3 | 0 | 3 |
| TADA1 | ZNF765 | 0.796903 | 3 | 0 | 3 |
| TADA1 | EPB41L5 | 0.792963 | 3 | 0 | 3 |
| TADA1 | HEATR5A | 0.785523 | 3 | 0 | 3 |
| TADA1 | WWP1 | 0.780855 | 3 | 0 | 3 |
| TADA1 | ZSCAN12 | 0.780526 | 3 | 0 | 3 |
| TADA1 | HMGN1 | 0.774996 | 3 | 0 | 3 |
| TADA1 | CDC73 | 0.774897 | 3 | 0 | 3 |
| TADA1 | LARP1B | 0.771162 | 3 | 0 | 3 |
| TADA1 | MED17 | 0.76942 | 3 | 0 | 3 |
| TADA1 | HMGB1 | 0.767605 | 3 | 0 | 3 |
| TADA1 | UBR7 | 0.766652 | 3 | 0 | 3 |
| TADA1 | NFXL1 | 0.764588 | 3 | 0 | 3 |
| TADA1 | PCID2 | 0.76294 | 3 | 0 | 3 |
| TADA1 | BRWD1 | 0.756235 | 3 | 0 | 3 |
| TADA1 | MRPS6 | 0.754943 | 3 | 0 | 3 |
| TADA1 | RLIM | 0.751649 | 3 | 0 | 3 |
| TADA1 | NAA25 | 0.748464 | 3 | 0 | 3 |
| TADA1 | SEC16A | 0.745222 | 3 | 0 | 3 |
For details and further investigation, click here
