| Full name: ATPase H+ transporting V1 subunit B2 | Alias Symbol: VATB|Vma2|HO57 | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 526 | HGNC ID: HGNC:854 | Ensembl Gene: ENSG00000147416 | OMIM ID: 606939 |
| Drug and gene relationship at DGIdb | |||
ATP6V1B2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04150 | mTOR signaling pathway | |
| hsa05110 | Vibrio cholerae infection | |
| hsa05120 | Epithelial cell signaling in Helicobacter pylori infection |
Expression of ATP6V1B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP6V1B2 | 526 | 201089_at | 0.4681 | 0.4570 | |
| GSE20347 | ATP6V1B2 | 526 | 201089_at | -0.1362 | 0.5311 | |
| GSE23400 | ATP6V1B2 | 526 | 201089_at | -0.0573 | 0.4204 | |
| GSE26886 | ATP6V1B2 | 526 | 201089_at | -1.8480 | 0.0000 | |
| GSE29001 | ATP6V1B2 | 526 | 201089_at | -0.1271 | 0.6820 | |
| GSE38129 | ATP6V1B2 | 526 | 201089_at | -0.0779 | 0.6415 | |
| GSE45670 | ATP6V1B2 | 526 | 201089_at | 0.2211 | 0.1689 | |
| GSE53622 | ATP6V1B2 | 526 | 36022 | 0.0199 | 0.6871 | |
| GSE53624 | ATP6V1B2 | 526 | 36022 | -0.3390 | 0.0000 | |
| GSE63941 | ATP6V1B2 | 526 | 201089_at | -0.3115 | 0.3969 | |
| GSE77861 | ATP6V1B2 | 526 | 201089_at | -0.0663 | 0.8646 | |
| GSE97050 | ATP6V1B2 | 526 | A_23_P31844 | 0.1386 | 0.5493 | |
| SRP007169 | ATP6V1B2 | 526 | RNAseq | -0.5585 | 0.2404 | |
| SRP008496 | ATP6V1B2 | 526 | RNAseq | -0.6457 | 0.0163 | |
| SRP064894 | ATP6V1B2 | 526 | RNAseq | 0.0940 | 0.5720 | |
| SRP133303 | ATP6V1B2 | 526 | RNAseq | 0.0861 | 0.6875 | |
| SRP159526 | ATP6V1B2 | 526 | RNAseq | -0.4275 | 0.0474 | |
| SRP193095 | ATP6V1B2 | 526 | RNAseq | -0.3393 | 0.0057 | |
| SRP219564 | ATP6V1B2 | 526 | RNAseq | 0.0679 | 0.8435 | |
| TCGA | ATP6V1B2 | 526 | RNAseq | 0.0227 | 0.6429 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATP6V1B2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP6V1B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP6V1B2 | 526 | 4 | 10 | 16 | |
| GSE20123 | ATP6V1B2 | 526 | 4 | 10 | 16 | |
| GSE43470 | ATP6V1B2 | 526 | 4 | 8 | 31 | |
| GSE46452 | ATP6V1B2 | 526 | 14 | 13 | 32 | |
| GSE47630 | ATP6V1B2 | 526 | 10 | 8 | 22 | |
| GSE54993 | ATP6V1B2 | 526 | 2 | 14 | 54 | |
| GSE54994 | ATP6V1B2 | 526 | 8 | 18 | 27 | |
| GSE60625 | ATP6V1B2 | 526 | 3 | 0 | 8 | |
| GSE74703 | ATP6V1B2 | 526 | 4 | 7 | 25 | |
| GSE74704 | ATP6V1B2 | 526 | 3 | 6 | 11 | |
| TCGA | ATP6V1B2 | 526 | 14 | 42 | 40 |
Total number of gains: 70; Total number of losses: 136; Total Number of normals: 282.
Somatic mutations of ATP6V1B2:
Generating mutation plots.
Highly correlated genes for ATP6V1B2:
Showing top 20/307 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP6V1B2 | IKZF5 | 0.795176 | 3 | 0 | 3 |
| ATP6V1B2 | MRPS18C | 0.789335 | 3 | 0 | 3 |
| ATP6V1B2 | HERPUD1 | 0.762325 | 3 | 0 | 3 |
| ATP6V1B2 | PDIK1L | 0.755032 | 3 | 0 | 3 |
| ATP6V1B2 | SERPINB9 | 0.754999 | 3 | 0 | 3 |
| ATP6V1B2 | NAE1 | 0.751211 | 3 | 0 | 3 |
| ATP6V1B2 | ZNF217 | 0.748573 | 3 | 0 | 3 |
| ATP6V1B2 | PHKB | 0.745772 | 3 | 0 | 3 |
| ATP6V1B2 | SLFN12 | 0.741394 | 3 | 0 | 3 |
| ATP6V1B2 | PPP1R8 | 0.735878 | 4 | 0 | 4 |
| ATP6V1B2 | FAM83D | 0.729191 | 3 | 0 | 3 |
| ATP6V1B2 | BZW1 | 0.720323 | 4 | 0 | 4 |
| ATP6V1B2 | FASTKD5 | 0.717659 | 3 | 0 | 3 |
| ATP6V1B2 | SLC35A3 | 0.712465 | 3 | 0 | 3 |
| ATP6V1B2 | EDEM1 | 0.711094 | 5 | 0 | 4 |
| ATP6V1B2 | CNOT6L | 0.710018 | 3 | 0 | 3 |
| ATP6V1B2 | SPPL2A | 0.704771 | 3 | 0 | 3 |
| ATP6V1B2 | OSTC | 0.704643 | 4 | 0 | 4 |
| ATP6V1B2 | NLRX1 | 0.703589 | 3 | 0 | 3 |
| ATP6V1B2 | SGPL1 | 0.696976 | 3 | 0 | 3 |
For details and further investigation, click here
