| Full name: hydroxysteroid dehydrogenase like 1 | Alias Symbol: SDR12C3 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 83693 | HGNC ID: HGNC:16475 | Ensembl Gene: ENSG00000103160 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HSDL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSDL1 | 83693 | 223248_at | 0.3606 | 0.3373 | |
| GSE26886 | HSDL1 | 83693 | 223248_at | -0.1761 | 0.3703 | |
| GSE45670 | HSDL1 | 83693 | 223248_at | 0.2499 | 0.0562 | |
| GSE53622 | HSDL1 | 83693 | 172147 | 0.1625 | 0.0904 | |
| GSE53624 | HSDL1 | 83693 | 172147 | 0.2071 | 0.0200 | |
| GSE63941 | HSDL1 | 83693 | 223248_at | -0.8377 | 0.1100 | |
| GSE77861 | HSDL1 | 83693 | 223248_at | 0.1971 | 0.2159 | |
| GSE97050 | HSDL1 | 83693 | A_23_P206324 | -0.0521 | 0.7980 | |
| SRP007169 | HSDL1 | 83693 | RNAseq | 0.3253 | 0.3608 | |
| SRP008496 | HSDL1 | 83693 | RNAseq | 0.4012 | 0.1426 | |
| SRP064894 | HSDL1 | 83693 | RNAseq | -0.0528 | 0.6941 | |
| SRP133303 | HSDL1 | 83693 | RNAseq | 0.4705 | 0.0019 | |
| SRP159526 | HSDL1 | 83693 | RNAseq | 0.2661 | 0.1508 | |
| SRP193095 | HSDL1 | 83693 | RNAseq | 0.2175 | 0.0291 | |
| SRP219564 | HSDL1 | 83693 | RNAseq | -0.0942 | 0.6856 | |
| TCGA | HSDL1 | 83693 | RNAseq | 0.0435 | 0.4516 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HSDL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSDL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSDL1 | 83693 | 4 | 4 | 22 | |
| GSE20123 | HSDL1 | 83693 | 4 | 4 | 22 | |
| GSE43470 | HSDL1 | 83693 | 2 | 10 | 31 | |
| GSE46452 | HSDL1 | 83693 | 37 | 2 | 20 | |
| GSE47630 | HSDL1 | 83693 | 11 | 9 | 20 | |
| GSE54993 | HSDL1 | 83693 | 3 | 4 | 63 | |
| GSE54994 | HSDL1 | 83693 | 8 | 10 | 35 | |
| GSE60625 | HSDL1 | 83693 | 4 | 0 | 7 | |
| GSE74703 | HSDL1 | 83693 | 2 | 7 | 27 | |
| GSE74704 | HSDL1 | 83693 | 3 | 2 | 15 | |
| TCGA | HSDL1 | 83693 | 25 | 17 | 54 |
Total number of gains: 103; Total number of losses: 69; Total Number of normals: 316.
Somatic mutations of HSDL1:
Generating mutation plots.
Highly correlated genes for HSDL1:
Showing top 20/437 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSDL1 | DHX38 | 0.8351 | 3 | 0 | 3 |
| HSDL1 | DHODH | 0.748895 | 3 | 0 | 3 |
| HSDL1 | MAK16 | 0.746975 | 3 | 0 | 3 |
| HSDL1 | KDELR2 | 0.737902 | 3 | 0 | 3 |
| HSDL1 | PSMD1 | 0.737466 | 3 | 0 | 3 |
| HSDL1 | FARS2 | 0.733826 | 3 | 0 | 3 |
| HSDL1 | RILPL2 | 0.727032 | 3 | 0 | 3 |
| HSDL1 | APPL2 | 0.726615 | 3 | 0 | 3 |
| HSDL1 | TACO1 | 0.720731 | 3 | 0 | 3 |
| HSDL1 | SDHAF2 | 0.717175 | 4 | 0 | 4 |
| HSDL1 | PHF20 | 0.716995 | 3 | 0 | 3 |
| HSDL1 | FASTKD5 | 0.713016 | 3 | 0 | 3 |
| HSDL1 | DNAAF2 | 0.710332 | 3 | 0 | 3 |
| HSDL1 | MTM1 | 0.709839 | 3 | 0 | 3 |
| HSDL1 | C16orf70 | 0.707673 | 3 | 0 | 3 |
| HSDL1 | VAPB | 0.703622 | 3 | 0 | 3 |
| HSDL1 | TTC4 | 0.702798 | 4 | 0 | 3 |
| HSDL1 | MKRN1 | 0.702293 | 3 | 0 | 3 |
| HSDL1 | ZNF764 | 0.700046 | 3 | 0 | 3 |
| HSDL1 | NEK11 | 0.699843 | 3 | 0 | 3 |
For details and further investigation, click here
