| Full name: F-box protein 15 | Alias Symbol: MGC39671|FBX15 | ||
| Type: protein-coding gene | Cytoband: 18q22.3 | ||
| Entrez ID: 201456 | HGNC ID: HGNC:13617 | Ensembl Gene: ENSG00000141665 | OMIM ID: 609093 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO15 | 201456 | 231472_at | 0.2054 | 0.4393 | |
| GSE26886 | FBXO15 | 201456 | 231472_at | 0.6214 | 0.0214 | |
| GSE45670 | FBXO15 | 201456 | 231472_at | 0.4106 | 0.1859 | |
| GSE53622 | FBXO15 | 201456 | 39561 | 0.3847 | 0.0000 | |
| GSE53624 | FBXO15 | 201456 | 39561 | 0.5833 | 0.0000 | |
| GSE63941 | FBXO15 | 201456 | 231472_at | -0.8237 | 0.1563 | |
| GSE77861 | FBXO15 | 201456 | 231472_at | -0.0367 | 0.8660 | |
| GSE97050 | FBXO15 | 201456 | A_23_P342709 | 0.0778 | 0.7114 | |
| SRP159526 | FBXO15 | 201456 | RNAseq | 1.9968 | 0.0023 | |
| TCGA | FBXO15 | 201456 | RNAseq | 1.0337 | 0.0494 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FBXO15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO15 | 201456 | 0 | 10 | 20 | |
| GSE20123 | FBXO15 | 201456 | 0 | 10 | 20 | |
| GSE43470 | FBXO15 | 201456 | 0 | 6 | 37 | |
| GSE46452 | FBXO15 | 201456 | 1 | 26 | 32 | |
| GSE47630 | FBXO15 | 201456 | 5 | 21 | 14 | |
| GSE54993 | FBXO15 | 201456 | 9 | 0 | 61 | |
| GSE54994 | FBXO15 | 201456 | 1 | 18 | 34 | |
| GSE60625 | FBXO15 | 201456 | 0 | 4 | 7 | |
| GSE74703 | FBXO15 | 201456 | 0 | 6 | 30 | |
| GSE74704 | FBXO15 | 201456 | 0 | 8 | 12 | |
| TCGA | FBXO15 | 201456 | 7 | 46 | 43 |
Total number of gains: 23; Total number of losses: 155; Total Number of normals: 310.
Somatic mutations of FBXO15:
Generating mutation plots.
Highly correlated genes for FBXO15:
Showing top 20/115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO15 | ADAMTS13 | 0.835878 | 3 | 0 | 3 |
| FBXO15 | HK3 | 0.815215 | 3 | 0 | 3 |
| FBXO15 | BCL6B | 0.794973 | 3 | 0 | 3 |
| FBXO15 | CDC20B | 0.792872 | 3 | 0 | 3 |
| FBXO15 | SLC22A31 | 0.779671 | 3 | 0 | 3 |
| FBXO15 | BMF | 0.770599 | 3 | 0 | 3 |
| FBXO15 | GPT | 0.756673 | 3 | 0 | 3 |
| FBXO15 | SCARF2 | 0.753385 | 3 | 0 | 3 |
| FBXO15 | GZMM | 0.750952 | 3 | 0 | 3 |
| FBXO15 | NCR3 | 0.743739 | 3 | 0 | 3 |
| FBXO15 | PRR18 | 0.740657 | 3 | 0 | 3 |
| FBXO15 | ISYNA1 | 0.739238 | 3 | 0 | 3 |
| FBXO15 | ORM1 | 0.739177 | 3 | 0 | 3 |
| FBXO15 | CEMP1 | 0.716276 | 3 | 0 | 3 |
| FBXO15 | PNMA6A | 0.716032 | 3 | 0 | 3 |
| FBXO15 | ARSA | 0.712564 | 3 | 0 | 3 |
| FBXO15 | DOK7 | 0.711306 | 3 | 0 | 3 |
| FBXO15 | OR7A17 | 0.71111 | 3 | 0 | 3 |
| FBXO15 | KRTAP19-1 | 0.695149 | 3 | 0 | 3 |
| FBXO15 | TREM1 | 0.694053 | 3 | 0 | 3 |
For details and further investigation, click here
