| Full name: granzyme M | Alias Symbol: MET1|LMET1 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 3004 | HGNC ID: HGNC:4712 | Ensembl Gene: ENSG00000197540 | OMIM ID: 600311 |
| Drug and gene relationship at DGIdb | |||
Expression of GZMM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GZMM | 3004 | 207460_at | 0.0599 | 0.8544 | |
| GSE20347 | GZMM | 3004 | 207460_at | -0.0828 | 0.2617 | |
| GSE23400 | GZMM | 3004 | 207460_at | -0.1915 | 0.0000 | |
| GSE26886 | GZMM | 3004 | 207460_at | 0.0463 | 0.8109 | |
| GSE29001 | GZMM | 3004 | 207460_at | 0.0877 | 0.4288 | |
| GSE38129 | GZMM | 3004 | 207460_at | -0.2230 | 0.0037 | |
| GSE45670 | GZMM | 3004 | 207460_at | -0.0415 | 0.7437 | |
| GSE53622 | GZMM | 3004 | 80682 | -0.3300 | 0.0000 | |
| GSE53624 | GZMM | 3004 | 80682 | -0.3460 | 0.0000 | |
| GSE63941 | GZMM | 3004 | 207460_at | 0.2909 | 0.0560 | |
| GSE77861 | GZMM | 3004 | 207460_at | -0.1256 | 0.2762 | |
| GSE97050 | GZMM | 3004 | A_23_P130836 | 0.0783 | 0.7560 | |
| SRP133303 | GZMM | 3004 | RNAseq | -1.4927 | 0.0002 | |
| SRP219564 | GZMM | 3004 | RNAseq | 0.3670 | 0.4099 | |
| TCGA | GZMM | 3004 | RNAseq | 0.1161 | 0.8311 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GZMM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GZMM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GZMM | 3004 | 4 | 6 | 20 | |
| GSE20123 | GZMM | 3004 | 4 | 5 | 21 | |
| GSE43470 | GZMM | 3004 | 1 | 10 | 32 | |
| GSE46452 | GZMM | 3004 | 47 | 1 | 11 | |
| GSE47630 | GZMM | 3004 | 5 | 7 | 28 | |
| GSE54993 | GZMM | 3004 | 13 | 4 | 53 | |
| GSE54994 | GZMM | 3004 | 8 | 15 | 30 | |
| GSE60625 | GZMM | 3004 | 9 | 0 | 2 | |
| GSE74703 | GZMM | 3004 | 1 | 7 | 28 | |
| GSE74704 | GZMM | 3004 | 3 | 3 | 14 | |
| TCGA | GZMM | 3004 | 8 | 25 | 63 |
Total number of gains: 103; Total number of losses: 83; Total Number of normals: 302.
Somatic mutations of GZMM:
Generating mutation plots.
Highly correlated genes for GZMM:
Showing top 20/245 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GZMM | SLC25A47 | 0.80489 | 3 | 0 | 3 |
| GZMM | SIGLEC10 | 0.780895 | 3 | 0 | 3 |
| GZMM | SPACA3 | 0.778761 | 3 | 0 | 3 |
| GZMM | TMEM179 | 0.768187 | 3 | 0 | 3 |
| GZMM | PROCA1 | 0.767422 | 3 | 0 | 3 |
| GZMM | UFSP1 | 0.759529 | 3 | 0 | 3 |
| GZMM | FBXO15 | 0.750952 | 3 | 0 | 3 |
| GZMM | DNAH6 | 0.749212 | 3 | 0 | 3 |
| GZMM | ZMYND10 | 0.747686 | 4 | 0 | 4 |
| GZMM | RLN3 | 0.747332 | 3 | 0 | 3 |
| GZMM | ACP5 | 0.745737 | 3 | 0 | 3 |
| GZMM | FAM71A | 0.741526 | 4 | 0 | 4 |
| GZMM | KCNK9 | 0.736574 | 3 | 0 | 3 |
| GZMM | DNAH10 | 0.735905 | 3 | 0 | 3 |
| GZMM | LHX9 | 0.7199 | 3 | 0 | 3 |
| GZMM | SLC26A1 | 0.715283 | 6 | 0 | 5 |
| GZMM | MARCO | 0.709654 | 3 | 0 | 3 |
| GZMM | SLC35F3 | 0.705296 | 4 | 0 | 3 |
| GZMM | GPR182 | 0.701328 | 4 | 0 | 3 |
| GZMM | SPN | 0.699152 | 3 | 0 | 3 |
For details and further investigation, click here
