| Full name: Bcl2 modifying factor | Alias Symbol: FLJ00065 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 90427 | HGNC ID: HGNC:24132 | Ensembl Gene: ENSG00000104081 | OMIM ID: 606266 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of BMF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BMF | 90427 | 226530_at | 0.3375 | 0.4121 | |
| GSE26886 | BMF | 90427 | 226530_at | 1.0286 | 0.0000 | |
| GSE45670 | BMF | 90427 | 226530_at | 0.1541 | 0.0524 | |
| GSE53622 | BMF | 90427 | 176238 | 0.6115 | 0.0000 | |
| GSE53624 | BMF | 90427 | 6213 | 0.7400 | 0.0000 | |
| GSE63941 | BMF | 90427 | 226530_at | 0.4916 | 0.3005 | |
| GSE77861 | BMF | 90427 | 226530_at | 0.2514 | 0.1896 | |
| GSE97050 | BMF | 90427 | A_23_P379649 | 0.2792 | 0.2579 | |
| SRP007169 | BMF | 90427 | RNAseq | 1.9977 | 0.0088 | |
| SRP064894 | BMF | 90427 | RNAseq | 0.9608 | 0.0001 | |
| SRP133303 | BMF | 90427 | RNAseq | 0.6227 | 0.0001 | |
| SRP159526 | BMF | 90427 | RNAseq | 0.7863 | 0.1114 | |
| SRP193095 | BMF | 90427 | RNAseq | 0.7998 | 0.0045 | |
| SRP219564 | BMF | 90427 | RNAseq | 1.2058 | 0.0003 | |
| TCGA | BMF | 90427 | RNAseq | -0.1478 | 0.1524 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by BMF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BMF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BMF | 90427 | 4 | 5 | 21 | |
| GSE20123 | BMF | 90427 | 4 | 5 | 21 | |
| GSE43470 | BMF | 90427 | 4 | 6 | 33 | |
| GSE46452 | BMF | 90427 | 3 | 7 | 49 | |
| GSE47630 | BMF | 90427 | 8 | 11 | 21 | |
| GSE54993 | BMF | 90427 | 4 | 6 | 60 | |
| GSE54994 | BMF | 90427 | 5 | 7 | 41 | |
| GSE60625 | BMF | 90427 | 4 | 0 | 7 | |
| GSE74703 | BMF | 90427 | 4 | 5 | 27 | |
| GSE74704 | BMF | 90427 | 3 | 3 | 14 | |
| TCGA | BMF | 90427 | 11 | 17 | 68 |
Total number of gains: 54; Total number of losses: 72; Total Number of normals: 362.
Somatic mutations of BMF:
Generating mutation plots.
Highly correlated genes for BMF:
Showing top 20/269 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BMF | PAX6 | 0.831298 | 3 | 0 | 3 |
| BMF | KLHL26 | 0.805751 | 3 | 0 | 3 |
| BMF | ADAP1 | 0.802562 | 3 | 0 | 3 |
| BMF | ST8SIA1 | 0.784482 | 3 | 0 | 3 |
| BMF | WAS | 0.777234 | 4 | 0 | 4 |
| BMF | FBXO15 | 0.770599 | 3 | 0 | 3 |
| BMF | BCL2L12 | 0.767618 | 3 | 0 | 3 |
| BMF | LYL1 | 0.757254 | 4 | 0 | 4 |
| BMF | NAT14 | 0.754505 | 5 | 0 | 4 |
| BMF | ST6GALNAC2 | 0.751309 | 3 | 0 | 3 |
| BMF | LRFN3 | 0.746366 | 3 | 0 | 3 |
| BMF | TBC1D10C | 0.736393 | 3 | 0 | 3 |
| BMF | RELB | 0.736311 | 5 | 0 | 5 |
| BMF | MSR1 | 0.735227 | 4 | 0 | 4 |
| BMF | APBA2 | 0.732391 | 4 | 0 | 3 |
| BMF | TNFSF11 | 0.729847 | 3 | 0 | 3 |
| BMF | C6orf15 | 0.725415 | 3 | 0 | 3 |
| BMF | NTNG2 | 0.724644 | 3 | 0 | 3 |
| BMF | ZNF511 | 0.721492 | 4 | 0 | 4 |
| BMF | KRT25 | 0.721068 | 3 | 0 | 3 |
For details and further investigation, click here
