| Full name: FCH and double SH3 domains 2 | Alias Symbol: KIAA0769 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 9873 | HGNC ID: HGNC:29114 | Ensembl Gene: ENSG00000137478 | OMIM ID: 617556 |
| Drug and gene relationship at DGIdb | |||
Expression of FCHSD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCHSD2 | 9873 | 203620_s_at | 0.7219 | 0.3019 | |
| GSE20347 | FCHSD2 | 9873 | 203620_s_at | 0.6527 | 0.0042 | |
| GSE23400 | FCHSD2 | 9873 | 203620_s_at | 0.6354 | 0.0000 | |
| GSE26886 | FCHSD2 | 9873 | 203620_s_at | 0.9103 | 0.0173 | |
| GSE29001 | FCHSD2 | 9873 | 203620_s_at | 0.7293 | 0.0191 | |
| GSE38129 | FCHSD2 | 9873 | 203620_s_at | 0.2860 | 0.1642 | |
| GSE45670 | FCHSD2 | 9873 | 203620_s_at | -0.0697 | 0.8425 | |
| GSE53622 | FCHSD2 | 9873 | 25337 | 0.3882 | 0.0001 | |
| GSE53624 | FCHSD2 | 9873 | 128843 | 0.3706 | 0.0005 | |
| GSE63941 | FCHSD2 | 9873 | 203620_s_at | -0.8680 | 0.1223 | |
| GSE77861 | FCHSD2 | 9873 | 203620_s_at | 0.4898 | 0.1000 | |
| GSE97050 | FCHSD2 | 9873 | A_24_P302038 | 0.2044 | 0.3758 | |
| SRP007169 | FCHSD2 | 9873 | RNAseq | 0.8614 | 0.0271 | |
| SRP008496 | FCHSD2 | 9873 | RNAseq | 1.2929 | 0.0004 | |
| SRP064894 | FCHSD2 | 9873 | RNAseq | 0.4266 | 0.0280 | |
| SRP133303 | FCHSD2 | 9873 | RNAseq | 0.3774 | 0.1101 | |
| SRP159526 | FCHSD2 | 9873 | RNAseq | -0.1154 | 0.6904 | |
| SRP193095 | FCHSD2 | 9873 | RNAseq | 0.5932 | 0.0012 | |
| SRP219564 | FCHSD2 | 9873 | RNAseq | 0.1788 | 0.6590 | |
| TCGA | FCHSD2 | 9873 | RNAseq | -0.0582 | 0.3846 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FCHSD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCHSD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCHSD2 | 9873 | 10 | 6 | 14 | |
| GSE20123 | FCHSD2 | 9873 | 10 | 6 | 14 | |
| GSE43470 | FCHSD2 | 9873 | 9 | 3 | 31 | |
| GSE46452 | FCHSD2 | 9873 | 10 | 19 | 30 | |
| GSE47630 | FCHSD2 | 9873 | 8 | 12 | 20 | |
| GSE54993 | FCHSD2 | 9873 | 8 | 2 | 60 | |
| GSE54994 | FCHSD2 | 9873 | 9 | 15 | 29 | |
| GSE60625 | FCHSD2 | 9873 | 0 | 7 | 4 | |
| GSE74703 | FCHSD2 | 9873 | 7 | 2 | 27 | |
| GSE74704 | FCHSD2 | 9873 | 7 | 3 | 10 | |
| TCGA | FCHSD2 | 9873 | 29 | 27 | 40 |
Total number of gains: 107; Total number of losses: 102; Total Number of normals: 279.
Somatic mutations of FCHSD2:
Generating mutation plots.
Highly correlated genes for FCHSD2:
Showing top 20/845 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCHSD2 | ZFX | 0.777736 | 3 | 0 | 3 |
| FCHSD2 | SPNS1 | 0.77449 | 3 | 0 | 3 |
| FCHSD2 | FAM111B | 0.773395 | 3 | 0 | 3 |
| FCHSD2 | IWS1 | 0.764922 | 3 | 0 | 3 |
| FCHSD2 | LURAP1L | 0.760072 | 3 | 0 | 3 |
| FCHSD2 | CHML | 0.756784 | 4 | 0 | 4 |
| FCHSD2 | APOO | 0.751314 | 3 | 0 | 3 |
| FCHSD2 | PLEKHM3 | 0.743737 | 3 | 0 | 3 |
| FCHSD2 | ZSCAN21 | 0.735087 | 3 | 0 | 3 |
| FCHSD2 | FAM199X | 0.72954 | 3 | 0 | 3 |
| FCHSD2 | ZNF641 | 0.728936 | 3 | 0 | 3 |
| FCHSD2 | CENPBD1 | 0.718583 | 3 | 0 | 3 |
| FCHSD2 | GSK3B | 0.71568 | 3 | 0 | 3 |
| FCHSD2 | TAOK1 | 0.712445 | 3 | 0 | 3 |
| FCHSD2 | NQO2 | 0.711752 | 3 | 0 | 3 |
| FCHSD2 | USP31 | 0.710004 | 3 | 0 | 3 |
| FCHSD2 | METAP1D | 0.709217 | 3 | 0 | 3 |
| FCHSD2 | ACBD5 | 0.70686 | 3 | 0 | 3 |
| FCHSD2 | SBNO1 | 0.703776 | 4 | 0 | 4 |
| FCHSD2 | HRH1 | 0.697022 | 3 | 0 | 3 |
For details and further investigation, click here
