| Full name: strawberry notch homolog 1 | Alias Symbol: MOP3|FLJ10701|FLJ10833|Sno | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 55206 | HGNC ID: HGNC:22973 | Ensembl Gene: ENSG00000139697 | OMIM ID: 614274 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SBNO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SBNO1 | 55206 | 229528_at | 0.4756 | 0.2134 | |
| GSE20347 | SBNO1 | 55206 | 218737_at | 0.2018 | 0.3890 | |
| GSE23400 | SBNO1 | 55206 | 216161_at | 0.0102 | 0.7996 | |
| GSE26886 | SBNO1 | 55206 | 230407_at | -1.0183 | 0.0002 | |
| GSE29001 | SBNO1 | 55206 | 218737_at | 0.0317 | 0.9187 | |
| GSE38129 | SBNO1 | 55206 | 218737_at | 0.4062 | 0.0343 | |
| GSE45670 | SBNO1 | 55206 | 230407_at | -0.0747 | 0.6607 | |
| GSE53622 | SBNO1 | 55206 | 2432 | -0.1480 | 0.0791 | |
| GSE53624 | SBNO1 | 55206 | 2432 | 0.0719 | 0.4702 | |
| GSE63941 | SBNO1 | 55206 | 229528_at | 0.5135 | 0.2094 | |
| GSE77861 | SBNO1 | 55206 | 229528_at | 0.2490 | 0.1640 | |
| GSE97050 | SBNO1 | 55206 | A_33_P3298577 | -0.0062 | 0.9830 | |
| SRP007169 | SBNO1 | 55206 | RNAseq | 0.7766 | 0.0253 | |
| SRP008496 | SBNO1 | 55206 | RNAseq | 0.6390 | 0.0011 | |
| SRP064894 | SBNO1 | 55206 | RNAseq | -0.2671 | 0.1190 | |
| SRP133303 | SBNO1 | 55206 | RNAseq | -0.0149 | 0.8669 | |
| SRP159526 | SBNO1 | 55206 | RNAseq | 0.1529 | 0.5148 | |
| SRP193095 | SBNO1 | 55206 | RNAseq | 0.0050 | 0.9403 | |
| SRP219564 | SBNO1 | 55206 | RNAseq | -0.5390 | 0.0018 | |
| TCGA | SBNO1 | 55206 | RNAseq | 0.0493 | 0.3461 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SBNO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SBNO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SBNO1 | 55206 | 5 | 5 | 20 | |
| GSE20123 | SBNO1 | 55206 | 5 | 5 | 20 | |
| GSE43470 | SBNO1 | 55206 | 2 | 1 | 40 | |
| GSE46452 | SBNO1 | 55206 | 9 | 1 | 49 | |
| GSE47630 | SBNO1 | 55206 | 9 | 3 | 28 | |
| GSE54993 | SBNO1 | 55206 | 0 | 5 | 65 | |
| GSE54994 | SBNO1 | 55206 | 4 | 8 | 41 | |
| GSE60625 | SBNO1 | 55206 | 0 | 0 | 11 | |
| GSE74703 | SBNO1 | 55206 | 2 | 0 | 34 | |
| GSE74704 | SBNO1 | 55206 | 3 | 3 | 14 | |
| TCGA | SBNO1 | 55206 | 21 | 11 | 64 |
Total number of gains: 60; Total number of losses: 42; Total Number of normals: 386.
Somatic mutations of SBNO1:
Generating mutation plots.
Highly correlated genes for SBNO1:
Showing top 20/312 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SBNO1 | SLC7A6 | 0.855909 | 3 | 0 | 3 |
| SBNO1 | RCBTB1 | 0.852048 | 3 | 0 | 3 |
| SBNO1 | PARK7 | 0.851427 | 3 | 0 | 3 |
| SBNO1 | NUFIP2 | 0.817222 | 3 | 0 | 3 |
| SBNO1 | C2CD2 | 0.815922 | 3 | 0 | 3 |
| SBNO1 | AP3M2 | 0.81512 | 3 | 0 | 3 |
| SBNO1 | GPX7 | 0.806011 | 3 | 0 | 3 |
| SBNO1 | NAPEPLD | 0.799194 | 3 | 0 | 3 |
| SBNO1 | DYRK2 | 0.77863 | 3 | 0 | 3 |
| SBNO1 | SMCR8 | 0.778139 | 3 | 0 | 3 |
| SBNO1 | SMARCAD1 | 0.774671 | 3 | 0 | 3 |
| SBNO1 | MSL2 | 0.770818 | 3 | 0 | 3 |
| SBNO1 | ZNF354C | 0.770297 | 3 | 0 | 3 |
| SBNO1 | CLDN12 | 0.768795 | 3 | 0 | 3 |
| SBNO1 | ZNF607 | 0.767715 | 3 | 0 | 3 |
| SBNO1 | SRSF6 | 0.756231 | 4 | 0 | 4 |
| SBNO1 | INTS10 | 0.754253 | 3 | 0 | 3 |
| SBNO1 | TMTC4 | 0.745388 | 3 | 0 | 3 |
| SBNO1 | L3MBTL3 | 0.743343 | 3 | 0 | 3 |
| SBNO1 | SNAPIN | 0.741984 | 3 | 0 | 3 |
For details and further investigation, click here
