| Full name: CHM like Rab escort protein | Alias Symbol: REP-2 | ||
| Type: protein-coding gene | Cytoband: 1q43 | ||
| Entrez ID: 1122 | HGNC ID: HGNC:1941 | Ensembl Gene: ENSG00000203668 | OMIM ID: 118825 |
| Drug and gene relationship at DGIdb | |||
Expression of CHML:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHML | 1122 | 226350_at | 0.9568 | 0.0247 | |
| GSE20347 | CHML | 1122 | 206079_at | 0.1005 | 0.0705 | |
| GSE23400 | CHML | 1122 | 206079_at | -0.0178 | 0.5594 | |
| GSE26886 | CHML | 1122 | 226350_at | 1.1614 | 0.0058 | |
| GSE29001 | CHML | 1122 | 206079_at | -0.0461 | 0.7565 | |
| GSE38129 | CHML | 1122 | 206079_at | 0.1681 | 0.0026 | |
| GSE45670 | CHML | 1122 | 226350_at | 0.3229 | 0.2117 | |
| GSE53622 | CHML | 1122 | 116006 | 0.7109 | 0.0000 | |
| GSE53624 | CHML | 1122 | 116006 | 1.0643 | 0.0000 | |
| GSE63941 | CHML | 1122 | 226350_at | 0.1156 | 0.8851 | |
| GSE77861 | CHML | 1122 | 226350_at | 0.8445 | 0.0179 | |
| GSE97050 | CHML | 1122 | A_24_P712350 | 0.3002 | 0.2913 | |
| SRP007169 | CHML | 1122 | RNAseq | 1.9652 | 0.0000 | |
| SRP008496 | CHML | 1122 | RNAseq | 1.8185 | 0.0000 | |
| SRP064894 | CHML | 1122 | RNAseq | 0.4694 | 0.0492 | |
| SRP133303 | CHML | 1122 | RNAseq | 0.8366 | 0.0001 | |
| SRP159526 | CHML | 1122 | RNAseq | 0.6184 | 0.0246 | |
| SRP193095 | CHML | 1122 | RNAseq | 0.4744 | 0.0000 | |
| SRP219564 | CHML | 1122 | RNAseq | 1.1056 | 0.0560 | |
| TCGA | CHML | 1122 | RNAseq | 0.2860 | 0.0021 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by CHML expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHML:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHML | 1122 | 7 | 1 | 22 | |
| GSE20123 | CHML | 1122 | 7 | 1 | 22 | |
| GSE43470 | CHML | 1122 | 6 | 1 | 36 | |
| GSE46452 | CHML | 1122 | 4 | 2 | 53 | |
| GSE47630 | CHML | 1122 | 15 | 0 | 25 | |
| GSE54993 | CHML | 1122 | 0 | 6 | 64 | |
| GSE54994 | CHML | 1122 | 18 | 0 | 35 | |
| GSE60625 | CHML | 1122 | 0 | 0 | 11 | |
| GSE74703 | CHML | 1122 | 6 | 1 | 29 | |
| GSE74704 | CHML | 1122 | 2 | 0 | 18 | |
| TCGA | CHML | 1122 | 42 | 4 | 50 |
Total number of gains: 107; Total number of losses: 16; Total Number of normals: 365.
Somatic mutations of CHML:
Generating mutation plots.
Highly correlated genes for CHML:
Showing top 20/1088 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHML | ACACA | 0.805203 | 3 | 0 | 3 |
| CHML | PCYT1A | 0.780799 | 3 | 0 | 3 |
| CHML | POGLUT1 | 0.779307 | 3 | 0 | 3 |
| CHML | ZNF317 | 0.775563 | 3 | 0 | 3 |
| CHML | THOP1 | 0.77504 | 3 | 0 | 3 |
| CHML | EXT2 | 0.77306 | 3 | 0 | 3 |
| CHML | SPNS1 | 0.768189 | 3 | 0 | 3 |
| CHML | CLP1 | 0.765854 | 3 | 0 | 3 |
| CHML | PDE3B | 0.765336 | 3 | 0 | 3 |
| CHML | SH2D3C | 0.761769 | 3 | 0 | 3 |
| CHML | FCHSD2 | 0.756784 | 4 | 0 | 4 |
| CHML | RNF26 | 0.754955 | 3 | 0 | 3 |
| CHML | C18orf54 | 0.752978 | 5 | 0 | 5 |
| CHML | ZNF765 | 0.752728 | 3 | 0 | 3 |
| CHML | SLC1A5 | 0.748524 | 3 | 0 | 3 |
| CHML | TGFBRAP1 | 0.747292 | 3 | 0 | 3 |
| CHML | SPSB2 | 0.745857 | 4 | 0 | 4 |
| CHML | CLCN7 | 0.743011 | 3 | 0 | 3 |
| CHML | ZCCHC7 | 0.741314 | 3 | 0 | 3 |
| CHML | BMP2 | 0.73851 | 3 | 0 | 3 |
For details and further investigation, click here
