| Full name: interacts with SUPT6H, CTD assembly factor 1 | Alias Symbol: DKFZp761G0123|FLJ10006|FLJ14655|FLJ32319 | ||
| Type: protein-coding gene | Cytoband: 2q14.3 | ||
| Entrez ID: 55677 | HGNC ID: HGNC:25467 | Ensembl Gene: ENSG00000163166 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IWS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IWS1 | 55677 | 224768_at | 0.3113 | 0.2860 | |
| GSE26886 | IWS1 | 55677 | 224768_at | 0.3451 | 0.0777 | |
| GSE45670 | IWS1 | 55677 | 224768_at | 0.2784 | 0.0154 | |
| GSE53622 | IWS1 | 55677 | 72717 | 0.2670 | 0.0000 | |
| GSE53624 | IWS1 | 55677 | 72717 | 0.3825 | 0.0000 | |
| GSE63941 | IWS1 | 55677 | 224768_at | -0.3741 | 0.2907 | |
| GSE77861 | IWS1 | 55677 | 224768_at | 0.6206 | 0.0003 | |
| GSE97050 | IWS1 | 55677 | A_23_P165574 | -0.0045 | 0.9890 | |
| SRP007169 | IWS1 | 55677 | RNAseq | 1.9992 | 0.0002 | |
| SRP008496 | IWS1 | 55677 | RNAseq | 1.2381 | 0.0020 | |
| SRP064894 | IWS1 | 55677 | RNAseq | 0.2927 | 0.0360 | |
| SRP133303 | IWS1 | 55677 | RNAseq | 0.4497 | 0.0080 | |
| SRP159526 | IWS1 | 55677 | RNAseq | 0.2827 | 0.1182 | |
| SRP193095 | IWS1 | 55677 | RNAseq | 0.2847 | 0.0019 | |
| SRP219564 | IWS1 | 55677 | RNAseq | 0.1414 | 0.5954 | |
| TCGA | IWS1 | 55677 | RNAseq | 0.0050 | 0.9173 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by IWS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IWS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IWS1 | 55677 | 6 | 3 | 21 | |
| GSE20123 | IWS1 | 55677 | 6 | 3 | 21 | |
| GSE43470 | IWS1 | 55677 | 2 | 1 | 40 | |
| GSE46452 | IWS1 | 55677 | 1 | 3 | 55 | |
| GSE47630 | IWS1 | 55677 | 6 | 0 | 34 | |
| GSE54993 | IWS1 | 55677 | 0 | 6 | 64 | |
| GSE54994 | IWS1 | 55677 | 11 | 0 | 42 | |
| GSE60625 | IWS1 | 55677 | 0 | 3 | 8 | |
| GSE74703 | IWS1 | 55677 | 2 | 1 | 33 | |
| GSE74704 | IWS1 | 55677 | 3 | 1 | 16 | |
| TCGA | IWS1 | 55677 | 22 | 8 | 66 |
Total number of gains: 59; Total number of losses: 29; Total Number of normals: 400.
Somatic mutations of IWS1:
Generating mutation plots.
Highly correlated genes for IWS1:
Showing top 20/1330 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IWS1 | HAUS6 | 0.79399 | 3 | 0 | 3 |
| IWS1 | TRAF3IP1 | 0.788447 | 4 | 0 | 4 |
| IWS1 | ACACA | 0.784885 | 3 | 0 | 3 |
| IWS1 | ZC3H18 | 0.781862 | 3 | 0 | 3 |
| IWS1 | HRH1 | 0.775902 | 3 | 0 | 3 |
| IWS1 | TMEM18 | 0.772731 | 3 | 0 | 3 |
| IWS1 | ANKRD40 | 0.767304 | 3 | 0 | 3 |
| IWS1 | GOSR1 | 0.765336 | 4 | 0 | 4 |
| IWS1 | FCHSD2 | 0.764922 | 3 | 0 | 3 |
| IWS1 | PPP1R10 | 0.754788 | 3 | 0 | 3 |
| IWS1 | KDSR | 0.752575 | 3 | 0 | 3 |
| IWS1 | PKP4 | 0.752542 | 3 | 0 | 3 |
| IWS1 | TBX1 | 0.752356 | 3 | 0 | 3 |
| IWS1 | IMPDH1 | 0.751362 | 4 | 0 | 3 |
| IWS1 | ISY1 | 0.750374 | 3 | 0 | 3 |
| IWS1 | USP14 | 0.748038 | 4 | 0 | 3 |
| IWS1 | COCH | 0.746991 | 5 | 0 | 4 |
| IWS1 | EFNB2 | 0.745579 | 4 | 0 | 4 |
| IWS1 | NEK3 | 0.743362 | 3 | 0 | 3 |
| IWS1 | TMTC4 | 0.742206 | 3 | 0 | 3 |
For details and further investigation, click here
