USP31

 

Full name: ubiquitin specific peptidase 31 Alias Symbol: KIAA1203
Type: protein-coding gene Cytoband: 16p12.2
Entrez ID: 57478 HGNC ID: HGNC:20060 Ensembl Gene: ENSG00000103404 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of USP31:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 USP31 57478 226035_at 0.2822 0.6477
GSE26886 USP31 57478 226035_at 0.0062 0.9881
GSE45670 USP31 57478 226035_at 0.2273 0.1695
GSE63941 USP31 57478 226035_at 1.6215 0.0131
GSE77861 USP31 57478 226035_at 0.8047 0.1504
GSE97050 USP31 57478 A_23_P206612 0.2661 0.2371
SRP007169 USP31 57478 RNAseq 1.1265 0.0049
SRP008496 USP31 57478 RNAseq 1.4978 0.0000
SRP064894 USP31 57478 RNAseq 0.4625 0.0270
SRP133303 USP31 57478 RNAseq 0.8647 0.0003
SRP159526 USP31 57478 RNAseq 0.7148 0.0036
SRP193095 USP31 57478 RNAseq 0.7164 0.0005
SRP219564 USP31 57478 RNAseq 0.8364 0.0956
TCGA USP31 57478 RNAseq 0.2040 0.0017

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by USP31 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of USP31:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 USP31 57478 6 4 20
GSE20123 USP31 57478 6 3 21
GSE43470 USP31 57478 3 3 37
GSE46452 USP31 57478 38 1 20
GSE47630 USP31 57478 11 6 23
GSE54993 USP31 57478 3 5 62
GSE54994 USP31 57478 4 10 39
GSE60625 USP31 57478 4 0 7
GSE74703 USP31 57478 3 2 31
GSE74704 USP31 57478 3 1 16
TCGA USP31 57478 19 13 64

Total number of gains: 100; Total number of losses: 48; Total Number of normals: 340.  


 

Somatic mutations of USP31:

 

Generating mutation plots.

 

Highly correlated genes for USP31:

 

Showing top 20/240 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
USP31AP2B10.769782303
USP31TINAGL10.742096303
USP31ZNF2750.726096303
USP31BRAT10.718409303
USP31FCHSD20.710004303
USP31MDM10.708298303
USP31CERS50.693781303
USP31ZNF5120.688475303
USP31ECSIT0.687989303
USP31DHX350.687111303
USP31PRSS230.686735303
USP31ASAP20.686259303
USP31FLVCR10.682195303
USP31SLC25A330.680873303
USP31DDX100.680752303
USP31HSF20.680401303
USP31SOX130.680119303
USP31FKBP90.678662303
USP31TARBP10.677608303
USP31INTS70.674951303

For details and further investigation, click here