| Full name: TAO kinase 1 | Alias Symbol: KIAA1361|MARKK|PSK2|MAP3K16|FLJ14314|TAO1 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 57551 | HGNC ID: HGNC:29259 | Ensembl Gene: ENSG00000160551 | OMIM ID: 610266 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAOK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAOK1 | 57551 | 224769_at | -0.0925 | 0.7951 | |
| GSE20347 | TAOK1 | 57551 | 216310_at | 0.2948 | 0.1312 | |
| GSE23400 | TAOK1 | 57551 | 216310_at | 0.0502 | 0.4408 | |
| GSE26886 | TAOK1 | 57551 | 224769_at | 0.8259 | 0.0002 | |
| GSE29001 | TAOK1 | 57551 | 216310_at | 0.2634 | 0.3296 | |
| GSE38129 | TAOK1 | 57551 | 216310_at | 0.1336 | 0.5126 | |
| GSE45670 | TAOK1 | 57551 | 224769_at | 0.0174 | 0.9349 | |
| GSE53622 | TAOK1 | 57551 | 50283 | 0.0751 | 0.1654 | |
| GSE53624 | TAOK1 | 57551 | 48498 | -0.1409 | 0.0007 | |
| GSE63941 | TAOK1 | 57551 | 224769_at | -0.9669 | 0.0174 | |
| GSE77861 | TAOK1 | 57551 | 224769_at | 0.4050 | 0.0574 | |
| GSE97050 | TAOK1 | 57551 | A_23_P38457 | 0.1281 | 0.5921 | |
| SRP007169 | TAOK1 | 57551 | RNAseq | 1.2134 | 0.0015 | |
| SRP008496 | TAOK1 | 57551 | RNAseq | 1.0731 | 0.0000 | |
| SRP064894 | TAOK1 | 57551 | RNAseq | -0.1183 | 0.6627 | |
| SRP133303 | TAOK1 | 57551 | RNAseq | 0.3114 | 0.0063 | |
| SRP159526 | TAOK1 | 57551 | RNAseq | -0.1228 | 0.6285 | |
| SRP193095 | TAOK1 | 57551 | RNAseq | 0.0645 | 0.4397 | |
| SRP219564 | TAOK1 | 57551 | RNAseq | -0.3583 | 0.3186 | |
| TCGA | TAOK1 | 57551 | RNAseq | -0.0339 | 0.6727 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TAOK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAOK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAOK1 | 57551 | 8 | 1 | 21 | |
| GSE20123 | TAOK1 | 57551 | 9 | 1 | 20 | |
| GSE43470 | TAOK1 | 57551 | 0 | 1 | 42 | |
| GSE46452 | TAOK1 | 57551 | 33 | 1 | 25 | |
| GSE47630 | TAOK1 | 57551 | 7 | 1 | 32 | |
| GSE54993 | TAOK1 | 57551 | 2 | 3 | 65 | |
| GSE54994 | TAOK1 | 57551 | 7 | 6 | 40 | |
| GSE60625 | TAOK1 | 57551 | 4 | 0 | 7 | |
| GSE74703 | TAOK1 | 57551 | 0 | 1 | 35 | |
| GSE74704 | TAOK1 | 57551 | 6 | 1 | 13 | |
| TCGA | TAOK1 | 57551 | 21 | 10 | 65 |
Total number of gains: 97; Total number of losses: 26; Total Number of normals: 365.
Somatic mutations of TAOK1:
Generating mutation plots.
Highly correlated genes for TAOK1:
Showing top 20/426 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAOK1 | THAP5 | 0.838881 | 3 | 0 | 3 |
| TAOK1 | CYP1A2 | 0.807961 | 3 | 0 | 3 |
| TAOK1 | CYP3A4 | 0.805898 | 4 | 0 | 4 |
| TAOK1 | TRRAP | 0.804791 | 3 | 0 | 3 |
| TAOK1 | C1orf131 | 0.782319 | 3 | 0 | 3 |
| TAOK1 | SORBS1 | 0.777001 | 5 | 0 | 5 |
| TAOK1 | KLHL24 | 0.770711 | 6 | 0 | 5 |
| TAOK1 | GLI3 | 0.770707 | 3 | 0 | 3 |
| TAOK1 | TTC30B | 0.7664 | 3 | 0 | 3 |
| TAOK1 | MTRF1L | 0.765747 | 6 | 0 | 5 |
| TAOK1 | ERN2 | 0.760622 | 5 | 0 | 4 |
| TAOK1 | ZC3H7B | 0.753078 | 6 | 0 | 4 |
| TAOK1 | SMCR8 | 0.752533 | 3 | 0 | 3 |
| TAOK1 | ADSL | 0.751823 | 3 | 0 | 3 |
| TAOK1 | NGRN | 0.749227 | 4 | 0 | 4 |
| TAOK1 | FGFR1 | 0.74542 | 5 | 0 | 4 |
| TAOK1 | PXK | 0.741958 | 3 | 0 | 3 |
| TAOK1 | MAP4K2 | 0.733891 | 3 | 0 | 3 |
| TAOK1 | FAM86C1 | 0.730655 | 3 | 0 | 3 |
| TAOK1 | TAF9B | 0.729159 | 3 | 0 | 3 |
For details and further investigation, click here
