| Full name: ficolin 3 | Alias Symbol: FCNH|HAKA1 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 8547 | HGNC ID: HGNC:3625 | Ensembl Gene: ENSG00000142748 | OMIM ID: 604973 |
| Drug and gene relationship at DGIdb | |||
Expression of FCN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCN3 | 8547 | 205866_at | -0.3444 | 0.5257 | |
| GSE20347 | FCN3 | 8547 | 205866_at | -0.1300 | 0.1742 | |
| GSE23400 | FCN3 | 8547 | 205866_at | -0.1149 | 0.0005 | |
| GSE26886 | FCN3 | 8547 | 205866_at | 0.1733 | 0.4240 | |
| GSE29001 | FCN3 | 8547 | 205866_at | -0.2364 | 0.0894 | |
| GSE38129 | FCN3 | 8547 | 205866_at | -0.0600 | 0.5457 | |
| GSE45670 | FCN3 | 8547 | 205866_at | 0.0261 | 0.8694 | |
| GSE53622 | FCN3 | 8547 | 51386 | 0.4467 | 0.0000 | |
| GSE53624 | FCN3 | 8547 | 51386 | 0.7024 | 0.0000 | |
| GSE63941 | FCN3 | 8547 | 205866_at | -0.0384 | 0.8164 | |
| GSE77861 | FCN3 | 8547 | 205866_at | -0.1128 | 0.3491 | |
| GSE97050 | FCN3 | 8547 | A_33_P3275741 | -0.2109 | 0.4061 | |
| SRP064894 | FCN3 | 8547 | RNAseq | 1.2694 | 0.0001 | |
| SRP159526 | FCN3 | 8547 | RNAseq | 0.4970 | 0.4075 | |
| SRP219564 | FCN3 | 8547 | RNAseq | 0.4583 | 0.3526 | |
| TCGA | FCN3 | 8547 | RNAseq | 0.1108 | 0.6867 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FCN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCN3 | 8547 | 0 | 6 | 24 | |
| GSE20123 | FCN3 | 8547 | 0 | 5 | 25 | |
| GSE43470 | FCN3 | 8547 | 4 | 6 | 33 | |
| GSE46452 | FCN3 | 8547 | 5 | 1 | 53 | |
| GSE47630 | FCN3 | 8547 | 8 | 3 | 29 | |
| GSE54993 | FCN3 | 8547 | 2 | 1 | 67 | |
| GSE54994 | FCN3 | 8547 | 10 | 4 | 39 | |
| GSE60625 | FCN3 | 8547 | 0 | 0 | 11 | |
| GSE74703 | FCN3 | 8547 | 3 | 4 | 29 | |
| GSE74704 | FCN3 | 8547 | 0 | 0 | 20 | |
| TCGA | FCN3 | 8547 | 11 | 23 | 62 |
Total number of gains: 43; Total number of losses: 53; Total Number of normals: 392.
Somatic mutations of FCN3:
Generating mutation plots.
Highly correlated genes for FCN3:
Showing top 20/192 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCN3 | CACNG8 | 0.779637 | 3 | 0 | 3 |
| FCN3 | DNAH10 | 0.751622 | 3 | 0 | 3 |
| FCN3 | NXF5 | 0.723804 | 3 | 0 | 3 |
| FCN3 | OR1J4 | 0.713334 | 3 | 0 | 3 |
| FCN3 | PLA2G12B | 0.704004 | 3 | 0 | 3 |
| FCN3 | KRTAP2-1 | 0.70116 | 3 | 0 | 3 |
| FCN3 | SIGLEC7 | 0.694167 | 3 | 0 | 3 |
| FCN3 | ZNF527 | 0.688883 | 3 | 0 | 3 |
| FCN3 | TPH2 | 0.681511 | 3 | 0 | 3 |
| FCN3 | SHC2 | 0.678906 | 3 | 0 | 3 |
| FCN3 | ATCAY | 0.678338 | 4 | 0 | 4 |
| FCN3 | NPBWR1 | 0.674884 | 3 | 0 | 3 |
| FCN3 | KRTAP4-8 | 0.673099 | 4 | 0 | 3 |
| FCN3 | OR4D1 | 0.669755 | 3 | 0 | 3 |
| FCN3 | TXNDC2 | 0.668555 | 3 | 0 | 3 |
| FCN3 | PEX6 | 0.646401 | 4 | 0 | 3 |
| FCN3 | TMEM105 | 0.645264 | 4 | 0 | 3 |
| FCN3 | NLRP9 | 0.645188 | 3 | 0 | 3 |
| FCN3 | SNAP91 | 0.642567 | 4 | 0 | 3 |
| FCN3 | FAM71F1 | 0.641324 | 4 | 0 | 3 |
For details and further investigation, click here
