| Full name: neuropeptides B and W receptor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q11.23 | ||
| Entrez ID: 2831 | HGNC ID: HGNC:4522 | Ensembl Gene: ENSG00000183729 | OMIM ID: 600730 |
| Drug and gene relationship at DGIdb | |||
Expression of NPBWR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPBWR1 | 2831 | 231752_at | -0.0098 | 0.9766 | |
| GSE26886 | NPBWR1 | 2831 | 231752_at | 0.3789 | 0.0043 | |
| GSE45670 | NPBWR1 | 2831 | 231752_at | 0.0197 | 0.8636 | |
| GSE53622 | NPBWR1 | 2831 | 45098 | 1.1255 | 0.0000 | |
| GSE53624 | NPBWR1 | 2831 | 45098 | 1.5559 | 0.0000 | |
| GSE63941 | NPBWR1 | 2831 | 231752_at | 0.1098 | 0.4147 | |
| GSE77861 | NPBWR1 | 2831 | 231752_at | 0.0353 | 0.7817 | |
| GSE97050 | NPBWR1 | 2831 | A_33_P3233219 | 0.1066 | 0.6331 | |
| SRP159526 | NPBWR1 | 2831 | RNAseq | 4.0704 | 0.0000 | |
| TCGA | NPBWR1 | 2831 | RNAseq | 5.4420 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by NPBWR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NPBWR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPBWR1 | 2831 | 15 | 2 | 13 | |
| GSE20123 | NPBWR1 | 2831 | 15 | 2 | 13 | |
| GSE43470 | NPBWR1 | 2831 | 14 | 3 | 26 | |
| GSE46452 | NPBWR1 | 2831 | 21 | 3 | 35 | |
| GSE47630 | NPBWR1 | 2831 | 23 | 1 | 16 | |
| GSE54993 | NPBWR1 | 2831 | 1 | 16 | 53 | |
| GSE54994 | NPBWR1 | 2831 | 28 | 0 | 25 | |
| GSE60625 | NPBWR1 | 2831 | 0 | 4 | 7 | |
| GSE74703 | NPBWR1 | 2831 | 13 | 2 | 21 | |
| GSE74704 | NPBWR1 | 2831 | 11 | 0 | 9 | |
| TCGA | NPBWR1 | 2831 | 43 | 9 | 44 |
Total number of gains: 184; Total number of losses: 42; Total Number of normals: 262.
Somatic mutations of NPBWR1:
Generating mutation plots.
Highly correlated genes for NPBWR1:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPBWR1 | DUSP9 | 0.782201 | 3 | 0 | 3 |
| NPBWR1 | SIRT6 | 0.764467 | 3 | 0 | 3 |
| NPBWR1 | ZNF524 | 0.763058 | 3 | 0 | 3 |
| NPBWR1 | TEKT2 | 0.758965 | 3 | 0 | 3 |
| NPBWR1 | TUBAL3 | 0.757449 | 3 | 0 | 3 |
| NPBWR1 | HK3 | 0.747104 | 3 | 0 | 3 |
| NPBWR1 | LTB4R2 | 0.741143 | 3 | 0 | 3 |
| NPBWR1 | ZFPM1 | 0.739244 | 3 | 0 | 3 |
| NPBWR1 | CABP1 | 0.733577 | 3 | 0 | 3 |
| NPBWR1 | CACNA1A | 0.726227 | 3 | 0 | 3 |
| NPBWR1 | TNNC2 | 0.724818 | 3 | 0 | 3 |
| NPBWR1 | CLDN14 | 0.716698 | 4 | 0 | 3 |
| NPBWR1 | PPP1R3F | 0.716406 | 3 | 0 | 3 |
| NPBWR1 | ADRA1A | 0.71451 | 3 | 0 | 3 |
| NPBWR1 | MLC1 | 0.712872 | 3 | 0 | 3 |
| NPBWR1 | PNMA2 | 0.705261 | 3 | 0 | 3 |
| NPBWR1 | ZNF205 | 0.705074 | 3 | 0 | 3 |
| NPBWR1 | POMC | 0.703778 | 3 | 0 | 3 |
| NPBWR1 | GFRA4 | 0.703147 | 4 | 0 | 4 |
| NPBWR1 | KRTAP4-8 | 0.699178 | 3 | 0 | 3 |
For details and further investigation, click here
