| Full name: fibroblast growth factor 11 | Alias Symbol: FHF3|FLJ16061|MGC45269|MGC102953 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 2256 | HGNC ID: HGNC:3667 | Ensembl Gene: ENSG00000161958 | OMIM ID: 601514 |
| Drug and gene relationship at DGIdb | |||
FGF11 involved pathways:
Expression of FGF11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGF11 | 2256 | 227271_at | 0.6101 | 0.5238 | |
| GSE26886 | FGF11 | 2256 | 227271_at | 0.2163 | 0.4307 | |
| GSE45670 | FGF11 | 2256 | 227271_at | 0.6195 | 0.0115 | |
| GSE63941 | FGF11 | 2256 | 227271_at | 0.8741 | 0.1504 | |
| GSE77861 | FGF11 | 2256 | 227271_at | 0.1250 | 0.7509 | |
| GSE97050 | FGF11 | 2256 | A_33_P3333282 | 0.0848 | 0.7304 | |
| SRP007169 | FGF11 | 2256 | RNAseq | -1.6901 | 0.0088 | |
| SRP008496 | FGF11 | 2256 | RNAseq | -1.4406 | 0.0038 | |
| SRP064894 | FGF11 | 2256 | RNAseq | -0.7347 | 0.0111 | |
| SRP133303 | FGF11 | 2256 | RNAseq | 0.2038 | 0.6097 | |
| SRP159526 | FGF11 | 2256 | RNAseq | -0.8111 | 0.0420 | |
| SRP219564 | FGF11 | 2256 | RNAseq | -0.7844 | 0.3477 | |
| TCGA | FGF11 | 2256 | RNAseq | 0.9547 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by FGF11 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FGF11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGF11 | 2256 | 4 | 2 | 24 | |
| GSE20123 | FGF11 | 2256 | 4 | 3 | 23 | |
| GSE43470 | FGF11 | 2256 | 1 | 4 | 38 | |
| GSE46452 | FGF11 | 2256 | 34 | 1 | 24 | |
| GSE47630 | FGF11 | 2256 | 7 | 1 | 32 | |
| GSE54993 | FGF11 | 2256 | 4 | 3 | 63 | |
| GSE54994 | FGF11 | 2256 | 5 | 8 | 40 | |
| GSE60625 | FGF11 | 2256 | 4 | 0 | 7 | |
| GSE74703 | FGF11 | 2256 | 1 | 2 | 33 | |
| GSE74704 | FGF11 | 2256 | 2 | 1 | 17 | |
| TCGA | FGF11 | 2256 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of FGF11:
Generating mutation plots.
Highly correlated genes for FGF11:
Showing top 20/178 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGF11 | WDR37 | 0.743485 | 3 | 0 | 3 |
| FGF11 | MTMR11 | 0.743014 | 3 | 0 | 3 |
| FGF11 | SH3BP2 | 0.720757 | 3 | 0 | 3 |
| FGF11 | HHAT | 0.719195 | 3 | 0 | 3 |
| FGF11 | DERL1 | 0.71219 | 3 | 0 | 3 |
| FGF11 | TRPC4AP | 0.711179 | 3 | 0 | 3 |
| FGF11 | ZNF706 | 0.710436 | 3 | 0 | 3 |
| FGF11 | ZNF165 | 0.709479 | 4 | 0 | 4 |
| FGF11 | ANP32E | 0.708949 | 3 | 0 | 3 |
| FGF11 | RAC3 | 0.704983 | 4 | 0 | 4 |
| FGF11 | CCDC85C | 0.700711 | 5 | 0 | 4 |
| FGF11 | NPC2 | 0.700218 | 3 | 0 | 3 |
| FGF11 | NCOA6 | 0.697538 | 3 | 0 | 3 |
| FGF11 | IL6R | 0.696765 | 4 | 0 | 3 |
| FGF11 | PSEN1 | 0.69469 | 3 | 0 | 3 |
| FGF11 | TM9SF1 | 0.690956 | 4 | 0 | 4 |
| FGF11 | IQCC | 0.690487 | 3 | 0 | 3 |
| FGF11 | KIF3A | 0.685295 | 3 | 0 | 3 |
| FGF11 | CALML5 | 0.683584 | 3 | 0 | 3 |
| FGF11 | XAB2 | 0.681558 | 3 | 0 | 3 |
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