| Full name: XPA binding protein 2 | Alias Symbol: HCNP|HCRN|SYF1|NTC90 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 56949 | HGNC ID: HGNC:14089 | Ensembl Gene: ENSG00000076924 | OMIM ID: 610850 |
| Drug and gene relationship at DGIdb | |||
Expression of XAB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XAB2 | 56949 | 218110_at | 0.3501 | 0.3676 | |
| GSE20347 | XAB2 | 56949 | 218110_at | 0.0631 | 0.4697 | |
| GSE23400 | XAB2 | 56949 | 218110_at | 0.1133 | 0.0433 | |
| GSE26886 | XAB2 | 56949 | 218110_at | 0.5237 | 0.0002 | |
| GSE29001 | XAB2 | 56949 | 218110_at | 0.0422 | 0.7642 | |
| GSE38129 | XAB2 | 56949 | 218110_at | 0.1966 | 0.1323 | |
| GSE45670 | XAB2 | 56949 | 218110_at | 0.0702 | 0.5066 | |
| GSE53622 | XAB2 | 56949 | 100741 | -0.0091 | 0.8876 | |
| GSE53624 | XAB2 | 56949 | 100741 | 0.2498 | 0.0002 | |
| GSE63941 | XAB2 | 56949 | 218110_at | 0.6939 | 0.0414 | |
| GSE77861 | XAB2 | 56949 | 218110_at | 0.0845 | 0.5209 | |
| GSE97050 | XAB2 | 56949 | A_23_P142013 | 0.3025 | 0.2237 | |
| SRP007169 | XAB2 | 56949 | RNAseq | -0.1439 | 0.7000 | |
| SRP008496 | XAB2 | 56949 | RNAseq | -0.1088 | 0.6813 | |
| SRP064894 | XAB2 | 56949 | RNAseq | 0.5336 | 0.0408 | |
| SRP133303 | XAB2 | 56949 | RNAseq | -0.0698 | 0.5976 | |
| SRP159526 | XAB2 | 56949 | RNAseq | 0.1373 | 0.5421 | |
| SRP193095 | XAB2 | 56949 | RNAseq | 0.2648 | 0.0037 | |
| SRP219564 | XAB2 | 56949 | RNAseq | 0.6924 | 0.1442 | |
| TCGA | XAB2 | 56949 | RNAseq | 0.0287 | 0.5393 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by XAB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XAB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | XAB2 | 56949 | 5 | 3 | 22 | |
| GSE20123 | XAB2 | 56949 | 4 | 2 | 24 | |
| GSE43470 | XAB2 | 56949 | 2 | 6 | 35 | |
| GSE46452 | XAB2 | 56949 | 47 | 1 | 11 | |
| GSE47630 | XAB2 | 56949 | 5 | 7 | 28 | |
| GSE54993 | XAB2 | 56949 | 16 | 3 | 51 | |
| GSE54994 | XAB2 | 56949 | 6 | 13 | 34 | |
| GSE60625 | XAB2 | 56949 | 9 | 0 | 2 | |
| GSE74703 | XAB2 | 56949 | 2 | 4 | 30 | |
| GSE74704 | XAB2 | 56949 | 1 | 2 | 17 | |
| TCGA | XAB2 | 56949 | 9 | 20 | 67 |
Total number of gains: 106; Total number of losses: 61; Total Number of normals: 321.
Somatic mutations of XAB2:
Generating mutation plots.
Highly correlated genes for XAB2:
Showing top 20/686 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XAB2 | MORC2 | 0.864684 | 3 | 0 | 3 |
| XAB2 | NLK | 0.852485 | 3 | 0 | 3 |
| XAB2 | RPS6KC1 | 0.812193 | 3 | 0 | 3 |
| XAB2 | ANKRD11 | 0.811907 | 3 | 0 | 3 |
| XAB2 | WDR54 | 0.801424 | 3 | 0 | 3 |
| XAB2 | CCDC59 | 0.794597 | 3 | 0 | 3 |
| XAB2 | CYP27C1 | 0.787952 | 3 | 0 | 3 |
| XAB2 | NUTF2 | 0.78654 | 3 | 0 | 3 |
| XAB2 | LMO1 | 0.783254 | 3 | 0 | 3 |
| XAB2 | KANK4 | 0.778167 | 3 | 0 | 3 |
| XAB2 | LSM14B | 0.776193 | 3 | 0 | 3 |
| XAB2 | DFFA | 0.772141 | 3 | 0 | 3 |
| XAB2 | CCNT1 | 0.768198 | 4 | 0 | 4 |
| XAB2 | UTP20 | 0.764507 | 3 | 0 | 3 |
| XAB2 | U2SURP | 0.75217 | 4 | 0 | 4 |
| XAB2 | UBR7 | 0.749258 | 3 | 0 | 3 |
| XAB2 | METTL23 | 0.748378 | 3 | 0 | 3 |
| XAB2 | DERL1 | 0.743277 | 3 | 0 | 3 |
| XAB2 | RPL7L1 | 0.738584 | 3 | 0 | 3 |
| XAB2 | G2E3 | 0.737279 | 3 | 0 | 3 |
For details and further investigation, click here
