| Full name: transient receptor potential cation channel subfamily C member 4 associated protein | Alias Symbol: DKFZP727M231|DKFZp586C1223|dJ756N5.2|TRRP4AP|PPP1R158 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 26133 | HGNC ID: HGNC:16181 | Ensembl Gene: ENSG00000100991 | OMIM ID: 608430 |
| Drug and gene relationship at DGIdb | |||
Expression of TRPC4AP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRPC4AP | 26133 | 212059_s_at | 0.6172 | 0.1131 | |
| GSE20347 | TRPC4AP | 26133 | 212059_s_at | 0.0711 | 0.5731 | |
| GSE23400 | TRPC4AP | 26133 | 212059_s_at | 0.0929 | 0.0071 | |
| GSE26886 | TRPC4AP | 26133 | 212059_s_at | -0.1088 | 0.5863 | |
| GSE29001 | TRPC4AP | 26133 | 212059_s_at | 0.2438 | 0.1677 | |
| GSE38129 | TRPC4AP | 26133 | 212059_s_at | 0.1511 | 0.0876 | |
| GSE45670 | TRPC4AP | 26133 | 212059_s_at | 0.1523 | 0.1531 | |
| GSE53622 | TRPC4AP | 26133 | 2525 | 0.2555 | 0.0000 | |
| GSE53624 | TRPC4AP | 26133 | 2525 | 0.3298 | 0.0000 | |
| GSE63941 | TRPC4AP | 26133 | 212059_s_at | 0.3822 | 0.3253 | |
| GSE77861 | TRPC4AP | 26133 | 212059_s_at | 0.1911 | 0.4725 | |
| GSE97050 | TRPC4AP | 26133 | A_23_P154801 | 0.4135 | 0.2110 | |
| SRP007169 | TRPC4AP | 26133 | RNAseq | -0.7207 | 0.0197 | |
| SRP008496 | TRPC4AP | 26133 | RNAseq | -0.4950 | 0.0216 | |
| SRP064894 | TRPC4AP | 26133 | RNAseq | 0.3988 | 0.0062 | |
| SRP133303 | TRPC4AP | 26133 | RNAseq | 0.2825 | 0.0205 | |
| SRP159526 | TRPC4AP | 26133 | RNAseq | -0.1809 | 0.3393 | |
| SRP193095 | TRPC4AP | 26133 | RNAseq | 0.0888 | 0.4323 | |
| SRP219564 | TRPC4AP | 26133 | RNAseq | 0.4182 | 0.1256 | |
| TCGA | TRPC4AP | 26133 | RNAseq | -0.0626 | 0.1456 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRPC4AP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRPC4AP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRPC4AP | 26133 | 16 | 0 | 14 | |
| GSE20123 | TRPC4AP | 26133 | 16 | 0 | 14 | |
| GSE43470 | TRPC4AP | 26133 | 13 | 0 | 30 | |
| GSE46452 | TRPC4AP | 26133 | 29 | 0 | 30 | |
| GSE47630 | TRPC4AP | 26133 | 25 | 0 | 15 | |
| GSE54993 | TRPC4AP | 26133 | 0 | 18 | 52 | |
| GSE54994 | TRPC4AP | 26133 | 25 | 0 | 28 | |
| GSE60625 | TRPC4AP | 26133 | 0 | 0 | 11 | |
| GSE74703 | TRPC4AP | 26133 | 11 | 0 | 25 | |
| GSE74704 | TRPC4AP | 26133 | 11 | 0 | 9 | |
| TCGA | TRPC4AP | 26133 | 49 | 3 | 44 |
Total number of gains: 195; Total number of losses: 21; Total Number of normals: 272.
Somatic mutations of TRPC4AP:
Generating mutation plots.
Highly correlated genes for TRPC4AP:
Showing top 20/553 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRPC4AP | PLEKHO2 | 0.765581 | 3 | 0 | 3 |
| TRPC4AP | MAPKAP1 | 0.765255 | 3 | 0 | 3 |
| TRPC4AP | DDX55 | 0.745045 | 3 | 0 | 3 |
| TRPC4AP | ISY1 | 0.74263 | 3 | 0 | 3 |
| TRPC4AP | ZNF830 | 0.73215 | 3 | 0 | 3 |
| TRPC4AP | NUP43 | 0.731239 | 3 | 0 | 3 |
| TRPC4AP | TBC1D4 | 0.72864 | 3 | 0 | 3 |
| TRPC4AP | SMCR8 | 0.726409 | 4 | 0 | 4 |
| TRPC4AP | GPR160 | 0.724357 | 3 | 0 | 3 |
| TRPC4AP | MOB3C | 0.723665 | 3 | 0 | 3 |
| TRPC4AP | MSTO1 | 0.718032 | 3 | 0 | 3 |
| TRPC4AP | TNFRSF1A | 0.717675 | 3 | 0 | 3 |
| TRPC4AP | HNRNPM | 0.715372 | 3 | 0 | 3 |
| TRPC4AP | EFEMP2 | 0.714366 | 3 | 0 | 3 |
| TRPC4AP | GPR137B | 0.712174 | 3 | 0 | 3 |
| TRPC4AP | FGF11 | 0.711179 | 3 | 0 | 3 |
| TRPC4AP | PDRG1 | 0.707977 | 6 | 0 | 5 |
| TRPC4AP | A1BG | 0.703099 | 3 | 0 | 3 |
| TRPC4AP | TRMT2A | 0.702385 | 3 | 0 | 3 |
| TRPC4AP | TMEM69 | 0.701892 | 3 | 0 | 3 |
For details and further investigation, click here
