| Full name: FKBP prolyl isomerase 8 | Alias Symbol: FKBP38|FKBPr38 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 23770 | HGNC ID: HGNC:3724 | Ensembl Gene: ENSG00000105701 | OMIM ID: 604840 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FKBP8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FKBP8 | 23770 | 40850_at | -0.1480 | 0.6479 | |
| GSE20347 | FKBP8 | 23770 | 40850_at | -0.6404 | 0.0000 | |
| GSE23400 | FKBP8 | 23770 | 40850_at | -0.3623 | 0.0000 | |
| GSE26886 | FKBP8 | 23770 | 40850_at | 0.1020 | 0.4243 | |
| GSE29001 | FKBP8 | 23770 | 40850_at | -0.4019 | 0.0204 | |
| GSE38129 | FKBP8 | 23770 | 40850_at | -0.5912 | 0.0002 | |
| GSE45670 | FKBP8 | 23770 | 208255_s_at | -0.1232 | 0.2726 | |
| GSE53622 | FKBP8 | 23770 | 69165 | -0.7886 | 0.0000 | |
| GSE53624 | FKBP8 | 23770 | 69165 | -0.4880 | 0.0000 | |
| GSE63941 | FKBP8 | 23770 | 40850_at | 1.5261 | 0.0000 | |
| GSE77861 | FKBP8 | 23770 | 40850_at | -0.1502 | 0.5262 | |
| GSE97050 | FKBP8 | 23770 | A_33_P3272990 | -0.4087 | 0.1791 | |
| SRP007169 | FKBP8 | 23770 | RNAseq | -2.2451 | 0.0000 | |
| SRP008496 | FKBP8 | 23770 | RNAseq | -2.0199 | 0.0000 | |
| SRP064894 | FKBP8 | 23770 | RNAseq | -0.2600 | 0.4160 | |
| SRP133303 | FKBP8 | 23770 | RNAseq | -0.8791 | 0.0000 | |
| SRP159526 | FKBP8 | 23770 | RNAseq | -0.5723 | 0.0147 | |
| SRP193095 | FKBP8 | 23770 | RNAseq | -0.6831 | 0.0000 | |
| SRP219564 | FKBP8 | 23770 | RNAseq | -0.6125 | 0.0964 | |
| TCGA | FKBP8 | 23770 | RNAseq | -0.0598 | 0.1381 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by FKBP8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FKBP8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FKBP8 | 23770 | 4 | 5 | 21 | |
| GSE20123 | FKBP8 | 23770 | 3 | 3 | 24 | |
| GSE43470 | FKBP8 | 23770 | 2 | 5 | 36 | |
| GSE46452 | FKBP8 | 23770 | 47 | 1 | 11 | |
| GSE47630 | FKBP8 | 23770 | 4 | 8 | 28 | |
| GSE54993 | FKBP8 | 23770 | 15 | 4 | 51 | |
| GSE54994 | FKBP8 | 23770 | 6 | 13 | 34 | |
| GSE60625 | FKBP8 | 23770 | 9 | 0 | 2 | |
| GSE74703 | FKBP8 | 23770 | 2 | 3 | 31 | |
| GSE74704 | FKBP8 | 23770 | 0 | 3 | 17 | |
| TCGA | FKBP8 | 23770 | 16 | 10 | 70 |
Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.
Somatic mutations of FKBP8:
Generating mutation plots.
Highly correlated genes for FKBP8:
Showing top 20/1021 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FKBP8 | ZNF747 | 0.821537 | 4 | 0 | 4 |
| FKBP8 | PMF1 | 0.761846 | 3 | 0 | 3 |
| FKBP8 | NDUFA2 | 0.759077 | 3 | 0 | 3 |
| FKBP8 | ZACN | 0.754001 | 3 | 0 | 3 |
| FKBP8 | FN3K | 0.727508 | 4 | 0 | 3 |
| FKBP8 | NFIA | 0.715931 | 3 | 0 | 3 |
| FKBP8 | FAM223B | 0.715689 | 4 | 0 | 4 |
| FKBP8 | GRPR | 0.711821 | 5 | 0 | 5 |
| FKBP8 | TMEM219 | 0.707032 | 4 | 0 | 4 |
| FKBP8 | SYN3 | 0.695507 | 4 | 0 | 3 |
| FKBP8 | ABHD14B | 0.69203 | 5 | 0 | 4 |
| FKBP8 | ZNF460 | 0.691633 | 3 | 0 | 3 |
| FKBP8 | PLIN4 | 0.690912 | 3 | 0 | 3 |
| FKBP8 | COX7B | 0.689183 | 3 | 0 | 3 |
| FKBP8 | CAPZB | 0.688497 | 5 | 0 | 4 |
| FKBP8 | ZNF625 | 0.687925 | 3 | 0 | 3 |
| FKBP8 | DGCR2 | 0.68749 | 4 | 0 | 4 |
| FKBP8 | MVB12A | 0.686225 | 4 | 0 | 3 |
| FKBP8 | NLRX1 | 0.686218 | 8 | 0 | 8 |
| FKBP8 | ZNF408 | 0.685679 | 4 | 0 | 4 |
For details and further investigation, click here
