| Full name: multivesicular body subunit 12A | Alias Symbol: FLJ32495 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 93343 | HGNC ID: HGNC:25153 | Ensembl Gene: ENSG00000141971 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MVB12A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MVB12A | 93343 | 227864_s_at | -0.0075 | 0.9905 | |
| GSE26886 | MVB12A | 93343 | 227864_s_at | -0.5281 | 0.0388 | |
| GSE45670 | MVB12A | 93343 | 227864_s_at | 0.1199 | 0.4589 | |
| GSE53622 | MVB12A | 93343 | 17305 | -0.4468 | 0.0000 | |
| GSE53624 | MVB12A | 93343 | 17305 | -0.4689 | 0.0000 | |
| GSE63941 | MVB12A | 93343 | 227864_s_at | 1.1725 | 0.0031 | |
| GSE77861 | MVB12A | 93343 | 227864_s_at | -0.1939 | 0.5727 | |
| SRP007169 | MVB12A | 93343 | RNAseq | -2.0741 | 0.0000 | |
| SRP008496 | MVB12A | 93343 | RNAseq | -1.7206 | 0.0000 | |
| SRP064894 | MVB12A | 93343 | RNAseq | 0.0030 | 0.9919 | |
| SRP133303 | MVB12A | 93343 | RNAseq | -0.7213 | 0.0000 | |
| SRP159526 | MVB12A | 93343 | RNAseq | -0.6200 | 0.0031 | |
| SRP193095 | MVB12A | 93343 | RNAseq | -0.5148 | 0.0000 | |
| SRP219564 | MVB12A | 93343 | RNAseq | 0.2596 | 0.4928 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by MVB12A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MVB12A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MVB12A | 93343 | 4 | 4 | 22 | |
| GSE20123 | MVB12A | 93343 | 3 | 2 | 25 | |
| GSE43470 | MVB12A | 93343 | 2 | 6 | 35 | |
| GSE46452 | MVB12A | 93343 | 47 | 1 | 11 | |
| GSE47630 | MVB12A | 93343 | 4 | 8 | 28 | |
| GSE54993 | MVB12A | 93343 | 15 | 4 | 51 | |
| GSE54994 | MVB12A | 93343 | 6 | 14 | 33 | |
| GSE60625 | MVB12A | 93343 | 9 | 0 | 2 | |
| GSE74703 | MVB12A | 93343 | 2 | 4 | 30 | |
| GSE74704 | MVB12A | 93343 | 0 | 2 | 18 | |
| TCGA | MVB12A | 93343 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of MVB12A:
Generating mutation plots.
Highly correlated genes for MVB12A:
Showing top 20/341 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MVB12A | CNKSR1 | 0.700347 | 3 | 0 | 3 |
| MVB12A | ARPC3 | 0.696365 | 3 | 0 | 3 |
| MVB12A | COPE | 0.694707 | 4 | 0 | 4 |
| MVB12A | DVL1 | 0.694174 | 3 | 0 | 3 |
| MVB12A | HSD17B8 | 0.686263 | 5 | 0 | 4 |
| MVB12A | FKBP8 | 0.686225 | 4 | 0 | 3 |
| MVB12A | STXBP2 | 0.685983 | 5 | 0 | 4 |
| MVB12A | RPUSD3 | 0.684604 | 3 | 0 | 3 |
| MVB12A | ARRDC1 | 0.683329 | 5 | 0 | 5 |
| MVB12A | PGLS | 0.68055 | 4 | 0 | 4 |
| MVB12A | RECQL5 | 0.680399 | 3 | 0 | 3 |
| MVB12A | KDF1 | 0.680071 | 3 | 0 | 3 |
| MVB12A | RPS6KB2 | 0.678517 | 3 | 0 | 3 |
| MVB12A | DCTN3 | 0.677808 | 4 | 0 | 4 |
| MVB12A | CHMP4C | 0.673122 | 3 | 0 | 3 |
| MVB12A | SYT15 | 0.670361 | 3 | 0 | 3 |
| MVB12A | MAP7 | 0.669104 | 4 | 0 | 4 |
| MVB12A | AP1M2 | 0.661303 | 7 | 0 | 7 |
| MVB12A | SNRNP35 | 0.65701 | 3 | 0 | 3 |
| MVB12A | RHOG | 0.652746 | 4 | 0 | 3 |
For details and further investigation, click here
