| Full name: transmembrane protein 219 | Alias Symbol: IGFBP-3R | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 124446 | HGNC ID: HGNC:25201 | Ensembl Gene: ENSG00000149932 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM219:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM219 | 124446 | 224981_at | -0.2862 | 0.4955 | |
| GSE26886 | TMEM219 | 124446 | 224981_at | -0.3497 | 0.1653 | |
| GSE45670 | TMEM219 | 124446 | 224981_at | -0.2868 | 0.0228 | |
| GSE53622 | TMEM219 | 124446 | 3887 | -0.4411 | 0.0000 | |
| GSE53624 | TMEM219 | 124446 | 96032 | -0.2676 | 0.0001 | |
| GSE63941 | TMEM219 | 124446 | 224981_at | -0.6932 | 0.1593 | |
| GSE77861 | TMEM219 | 124446 | 224981_at | -0.6744 | 0.0271 | |
| GSE97050 | TMEM219 | 124446 | A_23_P77562 | -0.0266 | 0.9310 | |
| SRP007169 | TMEM219 | 124446 | RNAseq | -1.0940 | 0.0169 | |
| SRP008496 | TMEM219 | 124446 | RNAseq | -0.9516 | 0.0091 | |
| SRP064894 | TMEM219 | 124446 | RNAseq | -0.3129 | 0.3408 | |
| SRP133303 | TMEM219 | 124446 | RNAseq | -0.2580 | 0.0642 | |
| SRP159526 | TMEM219 | 124446 | RNAseq | -0.6596 | 0.0091 | |
| SRP193095 | TMEM219 | 124446 | RNAseq | -0.7060 | 0.0000 | |
| SRP219564 | TMEM219 | 124446 | RNAseq | -0.1039 | 0.7777 | |
| TCGA | TMEM219 | 124446 | RNAseq | -0.2207 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM219 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM219:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM219 | 124446 | 5 | 5 | 20 | |
| GSE20123 | TMEM219 | 124446 | 5 | 4 | 21 | |
| GSE43470 | TMEM219 | 124446 | 3 | 3 | 37 | |
| GSE46452 | TMEM219 | 124446 | 38 | 1 | 20 | |
| GSE47630 | TMEM219 | 124446 | 11 | 7 | 22 | |
| GSE54993 | TMEM219 | 124446 | 3 | 5 | 62 | |
| GSE54994 | TMEM219 | 124446 | 5 | 9 | 39 | |
| GSE60625 | TMEM219 | 124446 | 4 | 0 | 7 | |
| GSE74703 | TMEM219 | 124446 | 3 | 2 | 31 | |
| GSE74704 | TMEM219 | 124446 | 3 | 2 | 15 | |
| TCGA | TMEM219 | 124446 | 20 | 11 | 65 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of TMEM219:
Generating mutation plots.
Highly correlated genes for TMEM219:
Showing top 20/893 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM219 | MKRN1 | 0.826073 | 3 | 0 | 3 |
| TMEM219 | SEMA4A | 0.807304 | 3 | 0 | 3 |
| TMEM219 | OS9 | 0.801107 | 3 | 0 | 3 |
| TMEM219 | ZNF564 | 0.783473 | 3 | 0 | 3 |
| TMEM219 | COG5 | 0.774351 | 3 | 0 | 3 |
| TMEM219 | CXorf40B | 0.772979 | 3 | 0 | 3 |
| TMEM219 | PTPRB | 0.761564 | 3 | 0 | 3 |
| TMEM219 | EFCAB14 | 0.759562 | 3 | 0 | 3 |
| TMEM219 | C2CD2 | 0.757687 | 4 | 0 | 4 |
| TMEM219 | MTIF3 | 0.75768 | 6 | 0 | 6 |
| TMEM219 | PPP1R11 | 0.755269 | 3 | 0 | 3 |
| TMEM219 | LIPT1 | 0.754184 | 3 | 0 | 3 |
| TMEM219 | STX10 | 0.753004 | 3 | 0 | 3 |
| TMEM219 | MKS1 | 0.751614 | 3 | 0 | 3 |
| TMEM219 | SOCS2 | 0.751539 | 3 | 0 | 3 |
| TMEM219 | ACSL5 | 0.747395 | 3 | 0 | 3 |
| TMEM219 | SF3A1 | 0.740935 | 3 | 0 | 3 |
| TMEM219 | ALG6 | 0.739457 | 3 | 0 | 3 |
| TMEM219 | MCCC1 | 0.738054 | 3 | 0 | 3 |
| TMEM219 | GRHPR | 0.737593 | 3 | 0 | 3 |
For details and further investigation, click here
