| Full name: zinc finger protein 408 | Alias Symbol: FLJ12827 | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 79797 | HGNC ID: HGNC:20041 | Ensembl Gene: ENSG00000175213 | OMIM ID: 616454 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF408:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF408 | 79797 | 219224_x_at | 0.2258 | 0.3186 | |
| GSE20347 | ZNF408 | 79797 | 219224_x_at | 0.0343 | 0.7346 | |
| GSE23400 | ZNF408 | 79797 | 219224_x_at | 0.0007 | 0.9884 | |
| GSE26886 | ZNF408 | 79797 | 219224_x_at | 0.4447 | 0.0150 | |
| GSE29001 | ZNF408 | 79797 | 219224_x_at | -0.1136 | 0.6368 | |
| GSE38129 | ZNF408 | 79797 | 219224_x_at | 0.0078 | 0.9281 | |
| GSE45670 | ZNF408 | 79797 | 219224_x_at | 0.1374 | 0.2134 | |
| GSE53622 | ZNF408 | 79797 | 101535 | 0.3266 | 0.0001 | |
| GSE53624 | ZNF408 | 79797 | 101535 | 0.3773 | 0.0000 | |
| GSE63941 | ZNF408 | 79797 | 219224_x_at | -0.1299 | 0.6415 | |
| GSE77861 | ZNF408 | 79797 | 219224_x_at | 0.0057 | 0.9741 | |
| GSE97050 | ZNF408 | 79797 | A_23_P32722 | 0.0772 | 0.7580 | |
| SRP007169 | ZNF408 | 79797 | RNAseq | -0.8603 | 0.1453 | |
| SRP064894 | ZNF408 | 79797 | RNAseq | 0.2866 | 0.1918 | |
| SRP133303 | ZNF408 | 79797 | RNAseq | -0.0392 | 0.8245 | |
| SRP159526 | ZNF408 | 79797 | RNAseq | -0.0359 | 0.9245 | |
| SRP193095 | ZNF408 | 79797 | RNAseq | -0.1012 | 0.4956 | |
| SRP219564 | ZNF408 | 79797 | RNAseq | 0.0975 | 0.7648 | |
| TCGA | ZNF408 | 79797 | RNAseq | 0.0102 | 0.8652 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF408 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF408:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF408 | 79797 | 3 | 7 | 20 | |
| GSE20123 | ZNF408 | 79797 | 3 | 6 | 21 | |
| GSE43470 | ZNF408 | 79797 | 2 | 4 | 37 | |
| GSE46452 | ZNF408 | 79797 | 8 | 5 | 46 | |
| GSE47630 | ZNF408 | 79797 | 3 | 9 | 28 | |
| GSE54993 | ZNF408 | 79797 | 3 | 0 | 67 | |
| GSE54994 | ZNF408 | 79797 | 1 | 10 | 42 | |
| GSE60625 | ZNF408 | 79797 | 0 | 0 | 11 | |
| GSE74703 | ZNF408 | 79797 | 2 | 2 | 32 | |
| GSE74704 | ZNF408 | 79797 | 2 | 4 | 14 | |
| TCGA | ZNF408 | 79797 | 12 | 19 | 65 |
Total number of gains: 39; Total number of losses: 66; Total Number of normals: 383.
Somatic mutations of ZNF408:
Generating mutation plots.
Highly correlated genes for ZNF408:
Showing top 20/649 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF408 | DCTN1 | 0.887791 | 3 | 0 | 3 |
| ZNF408 | TAF10 | 0.810145 | 3 | 0 | 3 |
| ZNF408 | CTDSP1 | 0.789984 | 4 | 0 | 4 |
| ZNF408 | GCDH | 0.786966 | 3 | 0 | 3 |
| ZNF408 | MZF1 | 0.786859 | 3 | 0 | 3 |
| ZNF408 | NSD1 | 0.778959 | 3 | 0 | 3 |
| ZNF408 | C12orf45 | 0.772592 | 3 | 0 | 3 |
| ZNF408 | ADAR | 0.770547 | 3 | 0 | 3 |
| ZNF408 | ZNF584 | 0.761348 | 3 | 0 | 3 |
| ZNF408 | TMEM115 | 0.75731 | 3 | 0 | 3 |
| ZNF408 | NOL12 | 0.751112 | 3 | 0 | 3 |
| ZNF408 | ZNF76 | 0.748089 | 3 | 0 | 3 |
| ZNF408 | KHSRP | 0.74551 | 4 | 0 | 4 |
| ZNF408 | MARCKSL1 | 0.744243 | 3 | 0 | 3 |
| ZNF408 | ADAM15 | 0.738799 | 4 | 0 | 4 |
| ZNF408 | ELMOD3 | 0.737337 | 3 | 0 | 3 |
| ZNF408 | SIK1 | 0.735121 | 3 | 0 | 3 |
| ZNF408 | GGN | 0.734749 | 3 | 0 | 3 |
| ZNF408 | SPTAN1 | 0.733783 | 3 | 0 | 3 |
| ZNF408 | RRS1 | 0.73323 | 3 | 0 | 3 |
For details and further investigation, click here
