| Full name: fructosamine 3 kinase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 64122 | HGNC ID: HGNC:24822 | Ensembl Gene: ENSG00000167363 | OMIM ID: 608425 |
| Drug and gene relationship at DGIdb | |||
Expression of FN3K:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FN3K | 64122 | 219744_at | 0.1281 | 0.6054 | |
| GSE20347 | FN3K | 64122 | 219744_at | -0.0021 | 0.9785 | |
| GSE23400 | FN3K | 64122 | 219744_at | -0.0410 | 0.1694 | |
| GSE26886 | FN3K | 64122 | 219744_at | 0.0318 | 0.8059 | |
| GSE29001 | FN3K | 64122 | 219744_at | -0.1677 | 0.2357 | |
| GSE38129 | FN3K | 64122 | 219744_at | -0.1018 | 0.1237 | |
| GSE45670 | FN3K | 64122 | 219744_at | 0.0174 | 0.8755 | |
| GSE53622 | FN3K | 64122 | 72130 | -0.6754 | 0.0000 | |
| GSE53624 | FN3K | 64122 | 72130 | -0.2237 | 0.0902 | |
| GSE63941 | FN3K | 64122 | 219744_at | 0.1605 | 0.3126 | |
| GSE77861 | FN3K | 64122 | 219744_at | 0.0302 | 0.8028 | |
| GSE97050 | FN3K | 64122 | A_23_P89215 | -0.5897 | 0.2027 | |
| SRP064894 | FN3K | 64122 | RNAseq | 0.2770 | 0.4394 | |
| SRP133303 | FN3K | 64122 | RNAseq | -0.7341 | 0.0059 | |
| SRP159526 | FN3K | 64122 | RNAseq | 0.5781 | 0.0199 | |
| SRP219564 | FN3K | 64122 | RNAseq | -0.3943 | 0.5492 | |
| TCGA | FN3K | 64122 | RNAseq | -0.6364 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FN3K expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FN3K:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FN3K | 64122 | 4 | 5 | 21 | |
| GSE20123 | FN3K | 64122 | 4 | 5 | 21 | |
| GSE43470 | FN3K | 64122 | 3 | 5 | 35 | |
| GSE46452 | FN3K | 64122 | 34 | 0 | 25 | |
| GSE47630 | FN3K | 64122 | 9 | 2 | 29 | |
| GSE54993 | FN3K | 64122 | 2 | 5 | 63 | |
| GSE54994 | FN3K | 64122 | 10 | 6 | 37 | |
| GSE60625 | FN3K | 64122 | 6 | 0 | 5 | |
| GSE74703 | FN3K | 64122 | 3 | 3 | 30 | |
| GSE74704 | FN3K | 64122 | 4 | 4 | 12 | |
| TCGA | FN3K | 64122 | 24 | 15 | 57 |
Total number of gains: 103; Total number of losses: 50; Total Number of normals: 335.
Somatic mutations of FN3K:
Generating mutation plots.
Highly correlated genes for FN3K:
Showing top 20/600 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FN3K | C9orf47 | 0.834173 | 3 | 0 | 3 |
| FN3K | DCTN1 | 0.770073 | 3 | 0 | 3 |
| FN3K | NFAM1 | 0.762557 | 3 | 0 | 3 |
| FN3K | DNAH11 | 0.760207 | 3 | 0 | 3 |
| FN3K | DVL1 | 0.740842 | 3 | 0 | 3 |
| FN3K | FKBP8 | 0.727508 | 4 | 0 | 3 |
| FN3K | PLCL1 | 0.726368 | 3 | 0 | 3 |
| FN3K | PRKACA | 0.717494 | 3 | 0 | 3 |
| FN3K | CTDSP1 | 0.716769 | 3 | 0 | 3 |
| FN3K | GIGYF1 | 0.716758 | 3 | 0 | 3 |
| FN3K | TMEM214 | 0.711823 | 3 | 0 | 3 |
| FN3K | SST | 0.711013 | 3 | 0 | 3 |
| FN3K | ZNF74 | 0.708863 | 3 | 0 | 3 |
| FN3K | LINGO1 | 0.70658 | 3 | 0 | 3 |
| FN3K | EPN1 | 0.70095 | 5 | 0 | 5 |
| FN3K | MTHFR | 0.700231 | 5 | 0 | 4 |
| FN3K | MAP4 | 0.697583 | 3 | 0 | 3 |
| FN3K | ICA1L | 0.694596 | 3 | 0 | 3 |
| FN3K | GBF1 | 0.692269 | 3 | 0 | 3 |
| FN3K | DMPK | 0.680834 | 3 | 0 | 3 |
For details and further investigation, click here
