| Full name: capping actin protein of muscle Z-line subunit beta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 832 | HGNC ID: HGNC:1491 | Ensembl Gene: ENSG00000077549 | OMIM ID: 601572 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CAPZB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAPZB | 832 | 37012_at | -0.0329 | 0.9401 | |
| GSE20347 | CAPZB | 832 | 37012_at | -0.7847 | 0.0000 | |
| GSE23400 | CAPZB | 832 | 37012_at | -0.2096 | 0.0002 | |
| GSE26886 | CAPZB | 832 | 37012_at | -0.8243 | 0.0001 | |
| GSE29001 | CAPZB | 832 | 37012_at | -0.3942 | 0.1560 | |
| GSE38129 | CAPZB | 832 | 37012_at | -0.5632 | 0.0000 | |
| GSE45670 | CAPZB | 832 | 37012_at | -0.2279 | 0.0830 | |
| GSE53622 | CAPZB | 832 | 31156 | -0.3849 | 0.0000 | |
| GSE53624 | CAPZB | 832 | 31156 | -0.3409 | 0.0000 | |
| GSE63941 | CAPZB | 832 | 37012_at | -0.3956 | 0.3870 | |
| GSE77861 | CAPZB | 832 | 37012_at | -0.6935 | 0.0008 | |
| GSE97050 | CAPZB | 832 | A_23_P126752 | 0.1578 | 0.5291 | |
| SRP007169 | CAPZB | 832 | RNAseq | -1.5162 | 0.0002 | |
| SRP008496 | CAPZB | 832 | RNAseq | -1.4111 | 0.0000 | |
| SRP064894 | CAPZB | 832 | RNAseq | -0.2236 | 0.1129 | |
| SRP133303 | CAPZB | 832 | RNAseq | -0.0675 | 0.7252 | |
| SRP159526 | CAPZB | 832 | RNAseq | -0.4723 | 0.0296 | |
| SRP193095 | CAPZB | 832 | RNAseq | -0.4911 | 0.0000 | |
| SRP219564 | CAPZB | 832 | RNAseq | -0.2456 | 0.3843 | |
| TCGA | CAPZB | 832 | RNAseq | 0.0574 | 0.1550 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CAPZB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAPZB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAPZB | 832 | 0 | 5 | 25 | |
| GSE20123 | CAPZB | 832 | 0 | 4 | 26 | |
| GSE43470 | CAPZB | 832 | 0 | 8 | 35 | |
| GSE46452 | CAPZB | 832 | 5 | 1 | 53 | |
| GSE47630 | CAPZB | 832 | 8 | 3 | 29 | |
| GSE54993 | CAPZB | 832 | 3 | 1 | 66 | |
| GSE54994 | CAPZB | 832 | 11 | 4 | 38 | |
| GSE60625 | CAPZB | 832 | 0 | 0 | 11 | |
| GSE74703 | CAPZB | 832 | 0 | 5 | 31 | |
| GSE74704 | CAPZB | 832 | 0 | 0 | 20 | |
| TCGA | CAPZB | 832 | 10 | 22 | 64 |
Total number of gains: 37; Total number of losses: 53; Total Number of normals: 398.
Somatic mutations of CAPZB:
Generating mutation plots.
Highly correlated genes for CAPZB:
Showing top 20/1223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAPZB | SMARCA4 | 0.823356 | 3 | 0 | 3 |
| CAPZB | LRRC36 | 0.773565 | 3 | 0 | 3 |
| CAPZB | PHLDB1 | 0.734619 | 3 | 0 | 3 |
| CAPZB | CLK4 | 0.727497 | 3 | 0 | 3 |
| CAPZB | PITHD1 | 0.725294 | 8 | 0 | 7 |
| CAPZB | CIDEB | 0.723917 | 5 | 0 | 5 |
| CAPZB | ACVR1B | 0.723876 | 4 | 0 | 3 |
| CAPZB | CASKIN2 | 0.720945 | 3 | 0 | 3 |
| CAPZB | PDK2 | 0.719996 | 3 | 0 | 3 |
| CAPZB | MYSM1 | 0.715492 | 3 | 0 | 3 |
| CAPZB | TMEM234 | 0.714251 | 5 | 0 | 4 |
| CAPZB | TRIM3 | 0.706704 | 4 | 0 | 3 |
| CAPZB | TLE4 | 0.704922 | 3 | 0 | 3 |
| CAPZB | HHLA1 | 0.702383 | 3 | 0 | 3 |
| CAPZB | FOXP4 | 0.702023 | 3 | 0 | 3 |
| CAPZB | RARG | 0.700734 | 5 | 0 | 4 |
| CAPZB | ZNF287 | 0.697548 | 3 | 0 | 3 |
| CAPZB | CNN3 | 0.695783 | 8 | 0 | 7 |
| CAPZB | ADAM11 | 0.695006 | 4 | 0 | 3 |
| CAPZB | RAP1A | 0.691979 | 9 | 0 | 9 |
For details and further investigation, click here
