FNDC3A

 

Full name: fibronectin type III domain containing 3A Alias Symbol: bA203I16.5|KIAA0970
Type: protein-coding gene Cytoband: 13q14.2
Entrez ID: 22862 HGNC ID: HGNC:20296 Ensembl Gene: ENSG00000102531 OMIM ID: 615794
Drug and gene relationship at DGIdb

 

Expression of FNDC3A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FNDC3A 22862 202304_at -0.2070 0.6072
GSE20347 FNDC3A 22862 202304_at -0.1627 0.4499
GSE23400 FNDC3A 22862 202304_at 0.2013 0.0281
GSE26886 FNDC3A 22862 202304_at 1.2311 0.0003
GSE29001 FNDC3A 22862 202304_at 0.0928 0.8274
GSE38129 FNDC3A 22862 202304_at -0.1682 0.3935
GSE45670 FNDC3A 22862 202304_at -0.3515 0.1006
GSE53622 FNDC3A 22862 37365 0.1140 0.2218
GSE53624 FNDC3A 22862 37365 0.0811 0.3980
GSE63941 FNDC3A 22862 202304_at -1.6431 0.0040
GSE77861 FNDC3A 22862 202304_at -0.0406 0.9264
GSE97050 FNDC3A 22862 A_23_P25503 0.2351 0.2726
SRP007169 FNDC3A 22862 RNAseq 0.6688 0.1396
SRP008496 FNDC3A 22862 RNAseq 0.7349 0.0037
SRP064894 FNDC3A 22862 RNAseq 0.2784 0.2484
SRP133303 FNDC3A 22862 RNAseq 0.0093 0.9504
SRP159526 FNDC3A 22862 RNAseq -0.2910 0.1961
SRP193095 FNDC3A 22862 RNAseq -0.1092 0.5793
SRP219564 FNDC3A 22862 RNAseq 0.3426 0.2972
TCGA FNDC3A 22862 RNAseq -0.3238 0.0000

Upregulated datasets: 1; Downregulated datasets: 1.  


 

Survival by FNDC3A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of FNDC3A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FNDC3A 22862 1 13 16
GSE20123 FNDC3A 22862 1 12 17
GSE43470 FNDC3A 22862 3 13 27
GSE46452 FNDC3A 22862 0 32 27
GSE47630 FNDC3A 22862 2 27 11
GSE54993 FNDC3A 22862 12 2 56
GSE54994 FNDC3A 22862 2 15 36
GSE60625 FNDC3A 22862 0 3 8
GSE74703 FNDC3A 22862 3 10 23
GSE74704 FNDC3A 22862 0 9 11
TCGA FNDC3A 22862 8 38 50

Total number of gains: 32; Total number of losses: 174; Total Number of normals: 282.  


 

Somatic mutations of FNDC3A:

 

Generating mutation plots.

 

Highly correlated genes for FNDC3A:

 

Showing top 20/742 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FNDC3AZNF70.782738303
FNDC3AMRPL90.767595303
FNDC3AHAUS60.766096303
FNDC3AKCTD180.758841303
FNDC3AEIF4G30.755906303
FNDC3ABTG10.75467303
FNDC3AZNF7030.75313303
FNDC3AFMR10.749958403
FNDC3ATXNDC90.741047303
FNDC3ATHOC20.727943303
FNDC3AECD0.723321303
FNDC3ASNRPD20.72179303
FNDC3ALY750.713894303
FNDC3ACHIC10.711981403
FNDC3APMPCB0.710339403
FNDC3APTAR10.707966303
FNDC3ACYB5D10.707088404
FNDC3ABRAP0.699475403
FNDC3AZNF700.69268303
FNDC3AWDR860.692087404

For details and further investigation, click here