| Full name: thioredoxin domain containing 9 | Alias Symbol: APACD | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 10190 | HGNC ID: HGNC:24110 | Ensembl Gene: ENSG00000115514 | OMIM ID: 612564 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TXNDC9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TXNDC9 | 10190 | 211758_x_at | 0.3578 | 0.6454 | |
| GSE20347 | TXNDC9 | 10190 | 211758_x_at | -0.0597 | 0.7955 | |
| GSE23400 | TXNDC9 | 10190 | 211758_x_at | 0.3345 | 0.0000 | |
| GSE26886 | TXNDC9 | 10190 | 211758_x_at | -0.1280 | 0.7424 | |
| GSE29001 | TXNDC9 | 10190 | 211758_x_at | 0.0621 | 0.8678 | |
| GSE38129 | TXNDC9 | 10190 | 211758_x_at | 0.3002 | 0.0553 | |
| GSE45670 | TXNDC9 | 10190 | 211758_x_at | 0.4221 | 0.0071 | |
| GSE53622 | TXNDC9 | 10190 | 110963 | 0.3528 | 0.0000 | |
| GSE53624 | TXNDC9 | 10190 | 110963 | 0.1489 | 0.0998 | |
| GSE63941 | TXNDC9 | 10190 | 211758_x_at | -0.1285 | 0.8050 | |
| GSE77861 | TXNDC9 | 10190 | 211758_x_at | 0.0573 | 0.8326 | |
| GSE97050 | TXNDC9 | 10190 | A_24_P362646 | 0.8154 | 0.1057 | |
| SRP007169 | TXNDC9 | 10190 | RNAseq | 0.0198 | 0.9549 | |
| SRP008496 | TXNDC9 | 10190 | RNAseq | 0.3665 | 0.2231 | |
| SRP064894 | TXNDC9 | 10190 | RNAseq | 0.0347 | 0.8337 | |
| SRP133303 | TXNDC9 | 10190 | RNAseq | 0.3839 | 0.0054 | |
| SRP159526 | TXNDC9 | 10190 | RNAseq | -0.2472 | 0.4372 | |
| SRP193095 | TXNDC9 | 10190 | RNAseq | -0.2195 | 0.1781 | |
| SRP219564 | TXNDC9 | 10190 | RNAseq | -0.3557 | 0.2625 | |
| TCGA | TXNDC9 | 10190 | RNAseq | 0.2451 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TXNDC9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TXNDC9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TXNDC9 | 10190 | 6 | 2 | 22 | |
| GSE20123 | TXNDC9 | 10190 | 6 | 2 | 22 | |
| GSE43470 | TXNDC9 | 10190 | 3 | 1 | 39 | |
| GSE46452 | TXNDC9 | 10190 | 2 | 3 | 54 | |
| GSE47630 | TXNDC9 | 10190 | 7 | 0 | 33 | |
| GSE54993 | TXNDC9 | 10190 | 0 | 6 | 64 | |
| GSE54994 | TXNDC9 | 10190 | 10 | 0 | 43 | |
| GSE60625 | TXNDC9 | 10190 | 0 | 3 | 8 | |
| GSE74703 | TXNDC9 | 10190 | 3 | 1 | 32 | |
| GSE74704 | TXNDC9 | 10190 | 4 | 1 | 15 | |
| TCGA | TXNDC9 | 10190 | 34 | 5 | 57 |
Total number of gains: 75; Total number of losses: 24; Total Number of normals: 389.
Somatic mutations of TXNDC9:
Generating mutation plots.
Highly correlated genes for TXNDC9:
Showing top 20/865 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TXNDC9 | FAM110A | 0.769072 | 3 | 0 | 3 |
| TXNDC9 | LRRC28 | 0.75141 | 3 | 0 | 3 |
| TXNDC9 | FNDC3A | 0.741047 | 3 | 0 | 3 |
| TXNDC9 | EID2 | 0.737246 | 3 | 0 | 3 |
| TXNDC9 | ELK3 | 0.736557 | 3 | 0 | 3 |
| TXNDC9 | MRPL37 | 0.734611 | 4 | 0 | 4 |
| TXNDC9 | KTI12 | 0.731192 | 3 | 0 | 3 |
| TXNDC9 | THAP2 | 0.723916 | 3 | 0 | 3 |
| TXNDC9 | TTC39C | 0.716663 | 3 | 0 | 3 |
| TXNDC9 | POGLUT1 | 0.712585 | 3 | 0 | 3 |
| TXNDC9 | ELOF1 | 0.709109 | 3 | 0 | 3 |
| TXNDC9 | RBM7 | 0.706452 | 5 | 0 | 5 |
| TXNDC9 | SIKE1 | 0.699714 | 3 | 0 | 3 |
| TXNDC9 | LASP1 | 0.695218 | 4 | 0 | 4 |
| TXNDC9 | SUSD1 | 0.693645 | 4 | 0 | 3 |
| TXNDC9 | LGALS8 | 0.687805 | 3 | 0 | 3 |
| TXNDC9 | SRD5A3 | 0.686855 | 3 | 0 | 3 |
| TXNDC9 | SYPL1 | 0.682788 | 4 | 0 | 4 |
| TXNDC9 | RABIF | 0.67657 | 3 | 0 | 3 |
| TXNDC9 | TCF19 | 0.671485 | 3 | 0 | 3 |
For details and further investigation, click here
