| Full name: WD repeat domain 86 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 349136 | HGNC ID: HGNC:28020 | Ensembl Gene: ENSG00000187260 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WDR86:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR86 | 349136 | 243526_at | 0.0625 | 0.8800 | |
| GSE26886 | WDR86 | 349136 | 243526_at | 0.5916 | 0.0001 | |
| GSE45670 | WDR86 | 349136 | 235246_at | -0.1074 | 0.2758 | |
| GSE53622 | WDR86 | 349136 | 12022 | 1.2896 | 0.0000 | |
| GSE53624 | WDR86 | 349136 | 12022 | 1.1261 | 0.0000 | |
| GSE63941 | WDR86 | 349136 | 235246_at | -0.1025 | 0.5794 | |
| GSE77861 | WDR86 | 349136 | 235246_at | -0.3279 | 0.0027 | |
| GSE97050 | WDR86 | 349136 | A_33_P3341601 | 0.4136 | 0.1723 | |
| SRP064894 | WDR86 | 349136 | RNAseq | 1.6246 | 0.0002 | |
| SRP133303 | WDR86 | 349136 | RNAseq | 0.8373 | 0.0147 | |
| SRP159526 | WDR86 | 349136 | RNAseq | 1.1217 | 0.0784 | |
| SRP219564 | WDR86 | 349136 | RNAseq | 1.3292 | 0.0718 | |
| TCGA | WDR86 | 349136 | RNAseq | -0.4676 | 0.1276 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by WDR86 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR86:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR86 | 349136 | 2 | 4 | 24 | |
| GSE20123 | WDR86 | 349136 | 2 | 4 | 24 | |
| GSE43470 | WDR86 | 349136 | 2 | 5 | 36 | |
| GSE46452 | WDR86 | 349136 | 7 | 2 | 50 | |
| GSE47630 | WDR86 | 349136 | 5 | 9 | 26 | |
| GSE54993 | WDR86 | 349136 | 3 | 3 | 64 | |
| GSE54994 | WDR86 | 349136 | 5 | 8 | 40 | |
| GSE60625 | WDR86 | 349136 | 0 | 0 | 11 | |
| GSE74703 | WDR86 | 349136 | 2 | 4 | 30 | |
| GSE74704 | WDR86 | 349136 | 1 | 4 | 15 | |
| TCGA | WDR86 | 349136 | 27 | 25 | 44 |
Total number of gains: 56; Total number of losses: 68; Total Number of normals: 364.
Somatic mutations of WDR86:
Generating mutation plots.
Highly correlated genes for WDR86:
Showing top 20/211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR86 | CDK14 | 0.781039 | 3 | 0 | 3 |
| WDR86 | MYL6B | 0.751828 | 3 | 0 | 3 |
| WDR86 | GYPC | 0.739035 | 3 | 0 | 3 |
| WDR86 | STARD3NL | 0.731316 | 5 | 0 | 5 |
| WDR86 | ZNF358 | 0.727561 | 3 | 0 | 3 |
| WDR86 | CHIC1 | 0.726235 | 3 | 0 | 3 |
| WDR86 | FGFRL1 | 0.715004 | 4 | 0 | 3 |
| WDR86 | CNTD1 | 0.713822 | 3 | 0 | 3 |
| WDR86 | HSD11B1 | 0.712093 | 4 | 0 | 4 |
| WDR86 | CLDND2 | 0.71028 | 4 | 0 | 4 |
| WDR86 | GLT8D1 | 0.705601 | 4 | 0 | 4 |
| WDR86 | SPON2 | 0.704809 | 3 | 0 | 3 |
| WDR86 | IGSF6 | 0.703766 | 3 | 0 | 3 |
| WDR86 | CERKL | 0.70067 | 3 | 0 | 3 |
| WDR86 | HABP4 | 0.699359 | 3 | 0 | 3 |
| WDR86 | GALNT10 | 0.695709 | 4 | 0 | 4 |
| WDR86 | DOK1 | 0.695122 | 4 | 0 | 4 |
| WDR86 | FNDC3A | 0.692087 | 4 | 0 | 4 |
| WDR86 | HVCN1 | 0.691198 | 3 | 0 | 3 |
| WDR86 | C1RL | 0.688899 | 3 | 0 | 3 |
For details and further investigation, click here
