| Full name: aquaporin 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 363 | HGNC ID: HGNC:639 | Ensembl Gene: ENSG00000086159 | OMIM ID: 601383 |
| Drug and gene relationship at DGIdb | |||
Expression of AQP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AQP6 | 363 | 216219_at | 0.0349 | 0.9039 | |
| GSE20347 | AQP6 | 363 | 216219_at | 0.0267 | 0.7884 | |
| GSE23400 | AQP6 | 363 | 216219_at | -0.0584 | 0.0971 | |
| GSE26886 | AQP6 | 363 | 216219_at | 0.0307 | 0.7914 | |
| GSE29001 | AQP6 | 363 | 216219_at | -0.1979 | 0.1404 | |
| GSE38129 | AQP6 | 363 | 216219_at | -0.1414 | 0.2740 | |
| GSE45670 | AQP6 | 363 | 216219_at | 0.0228 | 0.8556 | |
| GSE53622 | AQP6 | 363 | 986 | 0.1664 | 0.0739 | |
| GSE53624 | AQP6 | 363 | 986 | 0.0738 | 0.4172 | |
| GSE63941 | AQP6 | 363 | 216219_at | 0.0417 | 0.7381 | |
| GSE77861 | AQP6 | 363 | 216219_at | -0.0776 | 0.3891 | |
| GSE97050 | AQP6 | 363 | A_33_P3422247 | -0.0177 | 0.9516 | |
| TCGA | AQP6 | 363 | RNAseq | -1.0208 | 0.0497 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AQP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AQP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AQP6 | 363 | 8 | 1 | 21 | |
| GSE20123 | AQP6 | 363 | 8 | 1 | 21 | |
| GSE43470 | AQP6 | 363 | 3 | 0 | 40 | |
| GSE46452 | AQP6 | 363 | 8 | 1 | 50 | |
| GSE47630 | AQP6 | 363 | 11 | 2 | 27 | |
| GSE54993 | AQP6 | 363 | 0 | 5 | 65 | |
| GSE54994 | AQP6 | 363 | 4 | 1 | 48 | |
| GSE60625 | AQP6 | 363 | 0 | 0 | 11 | |
| GSE74703 | AQP6 | 363 | 3 | 0 | 33 | |
| GSE74704 | AQP6 | 363 | 5 | 1 | 14 | |
| TCGA | AQP6 | 363 | 15 | 11 | 70 |
Total number of gains: 65; Total number of losses: 23; Total Number of normals: 400.
Somatic mutations of AQP6:
Generating mutation plots.
Highly correlated genes for AQP6:
Showing top 20/1033 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AQP6 | FOLH1 | 0.765448 | 5 | 0 | 5 |
| AQP6 | TRPM3 | 0.764127 | 6 | 0 | 6 |
| AQP6 | G6PC2 | 0.753122 | 4 | 0 | 4 |
| AQP6 | CER1 | 0.747872 | 4 | 0 | 4 |
| AQP6 | FGF14 | 0.731787 | 3 | 0 | 3 |
| AQP6 | SYT13 | 0.7305 | 3 | 0 | 3 |
| AQP6 | PRL | 0.712568 | 5 | 0 | 5 |
| AQP6 | HECW1 | 0.708968 | 5 | 0 | 5 |
| AQP6 | TCL6 | 0.708354 | 5 | 0 | 4 |
| AQP6 | P2RX6 | 0.698525 | 5 | 0 | 4 |
| AQP6 | RPS6KA6 | 0.697229 | 4 | 0 | 4 |
| AQP6 | ATP8B3 | 0.696945 | 4 | 0 | 4 |
| AQP6 | IQSEC3 | 0.695854 | 6 | 0 | 6 |
| AQP6 | SMOC1 | 0.695473 | 3 | 0 | 3 |
| AQP6 | DNAH6 | 0.694233 | 6 | 0 | 6 |
| AQP6 | DNAI2 | 0.691816 | 5 | 0 | 5 |
| AQP6 | CGA | 0.691461 | 6 | 0 | 6 |
| AQP6 | FUT9 | 0.691299 | 3 | 0 | 3 |
| AQP6 | KIF17 | 0.686589 | 6 | 0 | 6 |
| AQP6 | VEPH1 | 0.686262 | 3 | 0 | 3 |
For details and further investigation, click here
