| Full name: forkhead box L2 | Alias Symbol: BPES1 | ||
| Type: protein-coding gene | Cytoband: 3q22.3 | ||
| Entrez ID: 668 | HGNC ID: HGNC:1092 | Ensembl Gene: ENSG00000183770 | OMIM ID: 605597 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXL2 | 668 | 220102_at | 0.8395 | 0.4059 | |
| GSE20347 | FOXL2 | 668 | 220102_at | 0.6465 | 0.0106 | |
| GSE23400 | FOXL2 | 668 | 220102_at | 0.2167 | 0.0011 | |
| GSE26886 | FOXL2 | 668 | 220102_at | 1.0002 | 0.0020 | |
| GSE29001 | FOXL2 | 668 | 220102_at | 1.2192 | 0.0442 | |
| GSE38129 | FOXL2 | 668 | 220102_at | 1.0206 | 0.0001 | |
| GSE45670 | FOXL2 | 668 | 220102_at | 0.6482 | 0.2186 | |
| GSE53622 | FOXL2 | 668 | 94066 | 0.5821 | 0.0000 | |
| GSE53624 | FOXL2 | 668 | 94066 | 0.6031 | 0.0000 | |
| GSE63941 | FOXL2 | 668 | 220102_at | 1.4337 | 0.3164 | |
| GSE77861 | FOXL2 | 668 | 220102_at | 0.5701 | 0.1064 | |
| GSE97050 | FOXL2 | 668 | A_23_P110052 | 0.1219 | 0.5432 | |
| SRP159526 | FOXL2 | 668 | RNAseq | 4.9357 | 0.0000 | |
| SRP219564 | FOXL2 | 668 | RNAseq | 5.0669 | 0.0000 | |
| TCGA | FOXL2 | 668 | RNAseq | 3.5852 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by FOXL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXL2 | 668 | 17 | 0 | 13 | |
| GSE20123 | FOXL2 | 668 | 17 | 0 | 13 | |
| GSE43470 | FOXL2 | 668 | 22 | 0 | 21 | |
| GSE46452 | FOXL2 | 668 | 15 | 4 | 40 | |
| GSE47630 | FOXL2 | 668 | 18 | 3 | 19 | |
| GSE54993 | FOXL2 | 668 | 2 | 8 | 60 | |
| GSE54994 | FOXL2 | 668 | 32 | 1 | 20 | |
| GSE60625 | FOXL2 | 668 | 0 | 6 | 5 | |
| GSE74703 | FOXL2 | 668 | 19 | 0 | 17 | |
| GSE74704 | FOXL2 | 668 | 11 | 0 | 9 | |
| TCGA | FOXL2 | 668 | 62 | 4 | 30 |
Total number of gains: 215; Total number of losses: 26; Total Number of normals: 247.
Somatic mutations of FOXL2:
Generating mutation plots.
Highly correlated genes for FOXL2:
Showing top 20/229 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXL2 | C8G | 0.759304 | 3 | 0 | 3 |
| FOXL2 | LURAP1L | 0.752785 | 3 | 0 | 3 |
| FOXL2 | ADAP1 | 0.736031 | 3 | 0 | 3 |
| FOXL2 | ALOX12B | 0.721136 | 3 | 0 | 3 |
| FOXL2 | SCN9A | 0.720735 | 5 | 0 | 5 |
| FOXL2 | OR7D4 | 0.688317 | 3 | 0 | 3 |
| FOXL2 | IL24 | 0.686012 | 3 | 0 | 3 |
| FOXL2 | ZNF236 | 0.679973 | 4 | 0 | 3 |
| FOXL2 | IQCH | 0.679707 | 4 | 0 | 3 |
| FOXL2 | TCTE3 | 0.678641 | 3 | 0 | 3 |
| FOXL2 | BEX1 | 0.675148 | 3 | 0 | 3 |
| FOXL2 | NID2 | 0.671501 | 3 | 0 | 3 |
| FOXL2 | NTNG2 | 0.66758 | 4 | 0 | 3 |
| FOXL2 | PAGR1 | 0.666018 | 3 | 0 | 3 |
| FOXL2 | POLE4 | 0.665796 | 4 | 0 | 3 |
| FOXL2 | SLCO1A2 | 0.665768 | 4 | 0 | 3 |
| FOXL2 | BMF | 0.663765 | 4 | 0 | 3 |
| FOXL2 | HOXC11 | 0.66157 | 3 | 0 | 3 |
| FOXL2 | MS4A18 | 0.660727 | 3 | 0 | 3 |
| FOXL2 | SHISA2 | 0.65891 | 3 | 0 | 3 |
For details and further investigation, click here
