| Full name: PAXIP1 associated glutamate rich protein 1 | Alias Symbol: MGC4606|GAS|PA1 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 79447 | HGNC ID: HGNC:28707 | Ensembl Gene: ENSG00000280789 | OMIM ID: 612033 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PAGR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAGR1 | 79447 | 218300_at | 0.4251 | 0.3017 | |
| GSE20347 | PAGR1 | 79447 | 218300_at | 0.4535 | 0.0001 | |
| GSE23400 | PAGR1 | 79447 | 218300_at | 0.2209 | 0.0000 | |
| GSE26886 | PAGR1 | 79447 | 218300_at | 0.3936 | 0.0602 | |
| GSE29001 | PAGR1 | 79447 | 218300_at | 0.5347 | 0.0170 | |
| GSE38129 | PAGR1 | 79447 | 218300_at | 0.5020 | 0.0000 | |
| GSE45670 | PAGR1 | 79447 | 218300_at | 0.3638 | 0.0160 | |
| GSE63941 | PAGR1 | 79447 | 218300_at | 1.0054 | 0.0151 | |
| GSE77861 | PAGR1 | 79447 | 218300_at | 0.1101 | 0.5099 | |
| SRP007169 | PAGR1 | 79447 | RNAseq | 0.3067 | 0.4550 | |
| SRP008496 | PAGR1 | 79447 | RNAseq | 0.2593 | 0.3626 | |
| SRP064894 | PAGR1 | 79447 | RNAseq | 0.4049 | 0.0783 | |
| SRP133303 | PAGR1 | 79447 | RNAseq | 0.3443 | 0.0450 | |
| SRP159526 | PAGR1 | 79447 | RNAseq | 0.7377 | 0.0261 | |
| SRP193095 | PAGR1 | 79447 | RNAseq | 0.2231 | 0.0179 | |
| SRP219564 | PAGR1 | 79447 | RNAseq | 0.1589 | 0.5296 |
Upregulated datasets: 1; Downregulated datasets: 0.
Copy number change of PAGR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAGR1 | 79447 | 5 | 5 | 20 | |
| GSE20123 | PAGR1 | 79447 | 5 | 4 | 21 | |
| GSE43470 | PAGR1 | 79447 | 3 | 3 | 37 | |
| GSE46452 | PAGR1 | 79447 | 38 | 1 | 20 | |
| GSE47630 | PAGR1 | 79447 | 11 | 7 | 22 | |
| GSE54993 | PAGR1 | 79447 | 3 | 5 | 62 | |
| GSE54994 | PAGR1 | 79447 | 5 | 9 | 39 | |
| GSE60625 | PAGR1 | 79447 | 4 | 0 | 7 | |
| GSE74703 | PAGR1 | 79447 | 3 | 2 | 31 | |
| GSE74704 | PAGR1 | 79447 | 3 | 2 | 15 | |
| TCGA | PAGR1 | 79447 | 20 | 11 | 65 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of PAGR1:
Generating mutation plots.
Highly correlated genes for PAGR1:
Showing top 20/722 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAGR1 | LSM10 | 0.728826 | 3 | 0 | 3 |
| PAGR1 | C18orf54 | 0.726692 | 3 | 0 | 3 |
| PAGR1 | SPNS1 | 0.723675 | 4 | 0 | 4 |
| PAGR1 | COX6A1 | 0.716803 | 3 | 0 | 3 |
| PAGR1 | KIF22 | 0.713793 | 9 | 0 | 8 |
| PAGR1 | RPS15 | 0.710751 | 3 | 0 | 3 |
| PAGR1 | ZFP69B | 0.696656 | 4 | 0 | 4 |
| PAGR1 | TXNDC12 | 0.69154 | 3 | 0 | 3 |
| PAGR1 | MAZ | 0.685083 | 8 | 0 | 8 |
| PAGR1 | EARS2 | 0.679596 | 3 | 0 | 3 |
| PAGR1 | RNASEH2A | 0.679486 | 9 | 0 | 8 |
| PAGR1 | RNF26 | 0.670815 | 4 | 0 | 3 |
| PAGR1 | NMRAL1 | 0.670243 | 3 | 0 | 3 |
| PAGR1 | CDC20 | 0.666729 | 7 | 0 | 7 |
| PAGR1 | ASF1B | 0.666592 | 9 | 0 | 8 |
| PAGR1 | FOXL2 | 0.666018 | 3 | 0 | 3 |
| PAGR1 | RFC4 | 0.66411 | 7 | 0 | 6 |
| PAGR1 | LZTS3 | 0.663673 | 3 | 0 | 3 |
| PAGR1 | SOGA1 | 0.662894 | 5 | 0 | 4 |
| PAGR1 | MGRN1 | 0.661803 | 4 | 0 | 4 |
For details and further investigation, click here
