| Full name: interleukin 24 | Alias Symbol: mda-7|IL10B|Mob-5|C49A|FISP|IL-24 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 11009 | HGNC ID: HGNC:11346 | Ensembl Gene: ENSG00000162892 | OMIM ID: 604136 |
| Drug and gene relationship at DGIdb | |||
IL24 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04630 | Jak-STAT signaling pathway |
Expression of IL24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL24 | 11009 | 206569_at | 2.3745 | 0.1557 | |
| GSE20347 | IL24 | 11009 | 206569_at | 0.6584 | 0.0230 | |
| GSE23400 | IL24 | 11009 | 206569_at | 0.3639 | 0.0004 | |
| GSE26886 | IL24 | 11009 | 206569_at | 1.7575 | 0.0127 | |
| GSE29001 | IL24 | 11009 | 206569_at | 1.0399 | 0.0443 | |
| GSE38129 | IL24 | 11009 | 206569_at | 0.8858 | 0.0087 | |
| GSE45670 | IL24 | 11009 | 206569_at | 2.0033 | 0.0020 | |
| GSE53622 | IL24 | 11009 | 136211 | -0.3582 | 0.0002 | |
| GSE53624 | IL24 | 11009 | 136211 | -0.1735 | 0.0947 | |
| GSE63941 | IL24 | 11009 | 206569_at | -0.4479 | 0.5564 | |
| GSE77861 | IL24 | 11009 | 206569_at | 0.7583 | 0.0654 | |
| GSE97050 | IL24 | 11009 | A_33_P3232692 | 0.0478 | 0.8698 | |
| SRP133303 | IL24 | 11009 | RNAseq | 3.2510 | 0.0000 | |
| SRP159526 | IL24 | 11009 | RNAseq | 3.8729 | 0.0000 | |
| SRP193095 | IL24 | 11009 | RNAseq | 6.2179 | 0.0000 | |
| TCGA | IL24 | 11009 | RNAseq | 3.2956 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by IL24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL24 | 11009 | 11 | 0 | 19 | |
| GSE20123 | IL24 | 11009 | 11 | 0 | 19 | |
| GSE43470 | IL24 | 11009 | 7 | 0 | 36 | |
| GSE46452 | IL24 | 11009 | 3 | 1 | 55 | |
| GSE47630 | IL24 | 11009 | 14 | 0 | 26 | |
| GSE54993 | IL24 | 11009 | 0 | 6 | 64 | |
| GSE54994 | IL24 | 11009 | 14 | 0 | 39 | |
| GSE60625 | IL24 | 11009 | 0 | 0 | 11 | |
| GSE74703 | IL24 | 11009 | 7 | 0 | 29 | |
| GSE74704 | IL24 | 11009 | 5 | 0 | 15 | |
| TCGA | IL24 | 11009 | 45 | 3 | 48 |
Total number of gains: 117; Total number of losses: 10; Total Number of normals: 361.
Somatic mutations of IL24:
Generating mutation plots.
Highly correlated genes for IL24:
Showing top 20/323 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL24 | STRIP2 | 0.736133 | 4 | 0 | 4 |
| IL24 | CLDN24 | 0.734203 | 3 | 0 | 3 |
| IL24 | APLN | 0.73247 | 3 | 0 | 3 |
| IL24 | CYP27B1 | 0.729415 | 9 | 0 | 9 |
| IL24 | SH2D5 | 0.693898 | 6 | 0 | 5 |
| IL24 | ITPKA | 0.693149 | 3 | 0 | 3 |
| IL24 | LFNG | 0.687823 | 4 | 0 | 4 |
| IL24 | FOXL2 | 0.686012 | 3 | 0 | 3 |
| IL24 | POLM | 0.676558 | 3 | 0 | 3 |
| IL24 | GPR180 | 0.67513 | 4 | 0 | 4 |
| IL24 | SPRY4-IT1 | 0.673887 | 4 | 0 | 3 |
| IL24 | RIMS4 | 0.671279 | 4 | 0 | 3 |
| IL24 | FAM180B | 0.667984 | 3 | 0 | 3 |
| IL24 | BEST2 | 0.667574 | 3 | 0 | 3 |
| IL24 | IL20 | 0.66522 | 6 | 0 | 6 |
| IL24 | KRTAP19-1 | 0.656453 | 3 | 0 | 3 |
| IL24 | P2RX5 | 0.655942 | 4 | 0 | 4 |
| IL24 | TDGF1 | 0.655214 | 3 | 0 | 3 |
| IL24 | LAMC2 | 0.649703 | 9 | 0 | 8 |
| IL24 | MTFP1 | 0.648522 | 4 | 0 | 4 |
For details and further investigation, click here
